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Growing evidence implicates gut microbiota and their metabolites in the regulation of human cardiometabolic health. However, relatively few studies have examined circulating microbial metabolites and incident coronary heart disease (CHD). In this metabolomics study, Yulu Zheng and colleagues investigate associations between microbial metabolites and coronary heart disease, performing discovery and validation analyses using five different cohorts. Their findings show novel epidemiological evidence on the importance of gut microbial metabolism in CHD development.

Image Credit: Phylum via Pixabay

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