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Virus membrane-anchored molecular adjuvants and rabies vaccines

November 14, 2019

Virus membrane-anchored molecular adjuvants and rabies vaccines

Joseph R. Plummer and James P. McGettigan describe a novel mechanism by which to improve rabies vaccination by incorporating a membrane-anchored molecular adjuvant into the surface of the rabies virus particle that significantly enhances the speed and magnitude of the anti-rabies antibody responses and has the potential to improve the efficacy of currently used inactivated RABV-based vaccines. 

Image credit: Centers for Disease Control and Prevention, Wikimedia Commons

Leishmaniasis Call for Papers

We are currently seeking papers related to innovation in Leishmaniasis elimination and control.                                                                          Read the editorial to learn more about the submissions we are inviting. 

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11/14/2019

Viewpoints

Significance of amebiasis: 10 reasons why neglecting amebiasis might come back to bite us in the gut

Debbie-Ann T. Shirley and colleagues summarize 10 reasons why amebiasis is a global health problem in need of further attention to develop innovative and inexpensive point-of-care diagnostic and surveillance tools, novel treatment options, and effective preventive strategies to help end amebiasis transmission. Read the Viewpoint

Image credit: CDC’s Division of Parasitic Diseases, Wikimedia Commons

Significance of amebiasis: 10 reasons why neglecting amebiasis might come back to bite us in the gut

10/28/2019

Research Article

Potential of Rapid Diagnostic Tests for Home Use in Peru and Cambodia

Valerie A. Paz-Soldan and colleagues explore locals' thoughts in Peru and Cambodia about the possible availability of rapid diagnostic test devices to diagnose dengue and malaria at home and what would motivate them to use such a device instead of going directly to a health facility for the diagnosis. Read the Author Summary

Potential of Rapid Diagnostic Tests for Home Use in Peru and Cambodia

Image credit: Paz-Soldan VA, Morrison AC, Sopheab H, Schwarz J, Bauer KM, Mckenney JL, et al. (2019)

10/31/2019

Research Article

Photodynamic Therapy Combined with Antifungal Drugs against Chromoblastomycosis

Yongxuan Hu and colleagues provide the basis for the development of a new therapeutic approach to treat chromoblastomycosis and ALA-PDT combined with oral antifungal drugs constitutes a promising alternative method for the treatment of refractory and complex cases. Read the Author Summary

Photodynamic Therapy Combined with Antifungal Drugs against Chromoblastomycosis

Image credit: Hu Y, Qi X, Sun H, Lu Y, Hu Y, Chen X, et al. (2019)

11/01/2019

Research Article

The preventable efficacy of β-glucan against leptospirosis

Jiaqi Wang and colleagues present results that contribute to an explanation for the preventable mechanism of β-glucan against Leptospira infection and reveal that β-glucan and other immunostimulants can be potent and valuable agents for controlling Leptospira infection. Read the Author Summary

The preventable efficacy of β-glucan against leptospirosis

Image credit: Wang J, Jin Z, Zhang W, Xie X, Song N, Lv T, et al. (2019)

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