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Use of oral cholera vaccine as a vaccine probe to determine the burden of culture-negative cholera

March 14, 2019

Use of oral cholera vaccine as a vaccine probe to determine the burden of culture-negative cholera

Justin Im, Md. Taufiqul Islam, and colleagues use the oral cholera vaccine as a probe to investigate the reliability of conventional culture as a diagnostic for cholera by measuring the effectiveness of the vaccine against cholera culture-negative acute watery diarrhea and do not find any evidence of protection, implying that the culture diagnostics used are reliable. 

Image credit: CDC, Public Health Image Library

Flubendazole in Onchocerciasis

Explore our collection on flubendazole as a treatment for onchocerciasis.

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02/27/2019

Editorial

PLOS Neglected Tropical Diseases 2018 Reviewer and Editorial Board Thank You

PLOS and the PLOS Neglected Tropical Diseases team want to sincerely thank all of our Editorial Board Members, Guest Editors, and Reviewers for the journal in 2018. Your contributions of time and expertise support your research community, advance scientific progress, and continue to make PLOS Neglected Tropical Diseases a leader in its field. Read the Editorial here

PLOS Neglected Tropical Diseases 2018 Reviewer and Editorial Board Thank You

Recently Published Articles

Current Issue

Current Issue February 2019

03/14/2019

Formal Comment

Melioidosis: The hazards of incomplete peer-review

Direk Limmathurotsakul, Alfredo G. Torres, and colleagues address what they believe to be a failure of the peer-review process and the inadequate interpretation of recent advances in the melioidosis field in a recently published review on the topic in PLOS Neglected Tropical Diseases. You can read their Formal Comment here

Image credit: CDC, Dr. Todd Parker and Audra Marsh, Wikimedia Commons

Melioidosis: The hazards of incomplete peer-review

03/11/2019

Research Article

Active surveillance identified a neglected burden of macular cases of Post Kala-azar Dermal Leishmaniasis in West Bengal

In this study, Mitali Chatterjee, Ritika Sengupta, and colleagues aim to delineate the differences in the demographics of Post Kala-azar Dermal Leishmaniasis cases detected by active vs. passive surveillance over the last 15 years in West Bengal. Read the Author Summary

Active surveillance identified a neglected burden of macular cases of Post Kala-azar Dermal Leishmaniasis in West Bengal

Image credit: Sengupta R, Chowdhury SJ, Moulik S, Ghosh MK, Saha B, Das NK, et al. (2019)

03/08/2019

Research Article

Mapping of lymphatic filariasis in loiasis areas

Samuel Wanji, Peter U. Fischer, and colleagues provide a simple day blood-based algorithm for lymphatic filariasis mapping in loiasis areas and the results indicate that many districts that were formerly classified as endemic for lymphatic filariasis in Cameroon are non-endemic and do not require mass drug administration for its elimination. Read the Author Summary

Mapping of lymphatic filariasis in loiasis areas

Image credit: Wanji S, Esum ME, Njouendou AJ, Mbeng AA, Chounna Ndongmo PW, Abong RA, et al. (2019)

03/14/2019

Research Article

Lady beetle-derived harmonine affects survival, reproduction and stem cell proliferation of Schistosoma mansoni

In this study, Simone Haeberlein and colleagues assess the antischistosomal capacity of harmonine and observe remarkably pleiotropic effects of harmonine on physiological, cellular, and molecular processes in adult male and female Schistosoma mansoni. Read the Author Summary.

Lady beetle-derived harmonine affects survival, reproduction and stem cell proliferation of Schistosoma mansoni

Image credit: Kellershohn J, Thomas L, Grünweller A, Hartmann RK, Hardt M, Vilcinskas A, et al. (2019)

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