June 10, 2022

A mixed-methods approach to understanding domestic dog health and disease transmission risk in an indigenous reserve in Guyana, South America

Marissa S. Milstein and colleagues perform physical examinations and collect biological samples to assess Waiwai domestic dog health and administer questionnaires to characterize the role of dogs in the community and identify potential transmission pathways between wildlife, dogs, and humans.

Image credit: Milstein, et al.

Triple drug (IDA) mass drug administration for elimination of lymphatic filariasis

This collection reports results of clinical trials and community studies of the safety, efficacy, and acceptability of the triple drug regimen IDA (ivermectin plus DEC and Albendazole) as a mass drug administration (MDA) regimen for lymphatic filariasis (LF) elimination programmes.

The Collection

05/12/2022

Symposium

Occupational risk of cutaneous larva migrans: A case report and a systematic literature review

Angela Stufano and colleagues report a case of autochthonous cutaneous larva migrans in a dog breeder in southern Italy to highlight how the collaboration among specialists in a One Health perspective, including dermatologists, occupational physicians, veterinarians, and parasitologists, is essential for the correct diagnosis of zoonotic infection. Read the Symposium.

Image credit: Stufano, et al. pntd.0010330

Occupational risk of cutaneous larva migrans: A case report and a systematic literature review

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Current IssueMay 2022

04/28/2022

Review

Finding a chink in the armor: Update, limitations, and challenges toward successful antivirals against flaviviruses

Thamil Vaani Komarasamy and colleagues review the latest progress in the development of both new and repurposed direct-acting antivirals, host-targeting antivirals, and multitarget antivirals against flaviviruses, which have been evaluated both in vitro and in vivo, with an emphasis on their targets and mechanisms. Read the Review.

Image credit: Cynthia Goldsmith, P.E. Rollin, USCDCP, Wikimedia Commons

Finding a chink in the armor: Update, limitations, and challenges toward successful antivirals against flaviviruses

05/26/2022

Symposium

Bartonella quintana endocarditis in a child from Northern Manitoba, Canada

Carl Boodman and colleagues describe a case of Bartonella quintana endocarditis in an 11-year-old child from Northern Manitoba, Canada that demonstrates the neglected endemicity of B. quintana in Northern Canada and highlights the need for improved case finding and elucidation of specific risk factors for B. quintana infection in the Canadian North. Read the Symposium.

Image credit: Rovery, et al. (2006)

Bartonella quintana endocarditis in a child from Northern Manitoba, Canada

06/15/2022

Research Article

Paracoccidioidomycosis in people living with HIV/AIDS in Rio de Janeiro, Brazil

Eduardo Mastrangelo Marinho Falcão and colleagues highlight the importance of considering a paracoccidioidomycosis diagnosis in people living HIV/AIDS to prevent a late-onset treatment and progression to severe manifestations and unfavorable outcomes. Read the Author Summary.

Image credit: Falcão, et al.

05/23/2022

Research Article

What the snake leaves in its wake: Functional limitations and disabilities among snakebite victims in Ghanaian communities

Leslie Mawuli Aglanu and colleagues comine community estimates of mild to moderate complications with data on severe complications from the health system level to provide a more comprehensive overview of the overall snakebite burden. Read the Author Summary.

Image credit: Aglanu, et al.

05/23/2022

Research Article

Podoconiosis: Clinical spectrum and microscopic presentations

Wendemagegn Enbiale and colleagues provide a detailed description of the different clinical patterns, associated clinical findings and the histopathologic spectrum of podoconiosis at different stages of the disease to serve as a guide to classifying patients with podoconiosis for prognostic assessment and treatment decision. Read the Author Summary.