Advertisement
Extracellular vesicles of Trypanosoma cruzi tissue-culture cell-derived trypomastigotes: induction of physiological changes in non-parasitized culture cells

February 21, 2019

Extracellular vesicles of Trypanosoma cruzi tissue-culture cell-derived trypomastigotes: induction of physiological changes in non-parasitized culture cells

Antonio Osuna and colleagues confirm that extracellular vesicles of tissue-culture cell-derived trypomastigotes of the Pan4 strain increase cell parasitism and demonstrate that extracellular vesicles affect cell permeability in Vero cells and cardiomyocytes and raise intracellular Ca2+ levels, altering the actin filaments and arresting the cell cycle at the G0/G1 phases.

Image credit: Retana Moreira L, Rodríguez Serrano F, Osuna A (2019)

Flubendazole in Onchocerciasis

Explore our collection on flubendazole as a treatment for onchocerciasis.

Click Here

02/21/2019

From Innovation to Application

A modified approach to recover and enumerate Ascaris ova in wastewater and sludge

In this from Innovation to Application, Vivek B. Ravindran and colleagues seek to develop a recovery method for Ascaris ova with minimal processing time and less damage to ova and to compare the modified protocol with published methods. Read the piece here

Image credit: CDC Division of Parasitic Diseases, Wikimedia Commons

A modified approach to recover and enumerate Ascaris ova in wastewater and sludge

02/15/2019

Research Article

Spatio-temporal distribution of Trypanosoma cruzi in wild Chilean foci

Antonella Bacigalupo and colleagues assess spatial and temporal variations of T. cruzi infection, detecting the DTUs, by sampling triatomines and small mammals of the same areas in two contrasting seasons of the same year, using conventional and spatially-explicit statistical techniques. Read the Author Summary

Spatio-temporal distribution of Trypanosoma cruzi in wild Chilean foci

Image credit: Centers for Disease Control and Prevention, Wikimedia Commons

02/21/2019

Research Article

Profile of the tprK gene in primary syphilis patients based on next-generation sequencing

Tian-Ci Yang and colleagues reveal the profile of tprK in T. pallidum directly from patients with primary syphilis by employing next-generation sequencing and provide important insights into the understanding of the diversity of tprK  that contribute to further explorations of the mechanisms of long-term T. pallidum infection. Read the Author Summary.

Profile of the tprK gene in primary syphilis patients based on next-generation sequencing

Image credit: Centers for Disease Control and Prevention, Wikimedia Commons

02/21/2019

Research Article

Mother-to-child transmission and gestational syphilis: spatial-temporal epidemiology and demographics in a Brazilian region

In this study, Marcus Vinícius Pimenta Rodrigues and colleagues analyze cases of syphilis during pregnancy and mother-to-child transmission of syphilis in the Pontal do Paranapanema region of Brazil to help establish measures to control and eliminate the mother-to-child transmission of syphilis. Read the Author Summary

Mother-to-child transmission and gestational syphilis: spatial-temporal epidemiology and demographics in a Brazilian region

Image credit: Centers for Disease Control and Prevention, Wikimedia Commons

Get new content from PLOS Neglected Tropical Diseases in your inbox

Thank you! You have successfully subscribed to the PLOS Neglected Tropical Diseases newsletter.

Sorry, an error occurred while sending your subscription. Please try again later.

Try again