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Single-cell RNA sequencing of Plasmodium vivax sporozoites reveals stage- and species-specific transcriptomic signatures

August 4, 2022

Single-cell RNA sequencing of Plasmodium vivax sporozoites reveals stage- and species-specific transcriptomic signatures

Anthony A. Ruberto and colleagues provide new insights into the factors driving P. vivax sporozoite developmental trajectory and lay the groundwork for a more comprehensive P. vivax cell atlas.

Image credit: CDC, Wikimedia Commons

Scorpion Venom Call for Papers

Submit to this PLOS Neglected Tropical Diseases call for papers to help expand the global knowledge                                                                    on Scorpion Venom. New submission deadline, November 15th, 2022.

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08/04/2022

Viewpoints

Trypanosoma cruzi parasitemia in chronic Chagas disease: Insights from hierarchical modeling

Fernando Abad-Franch uses publicly available, real-life data to illustrate how the hierarchical-modeling approach can be used in practice to estimate θ and p and to investigate whether and how those parameters vary in the frequency of T. cruzi parasitemia pulses and the intensity of that parasitemia in chronic Chagas disease patients.

Image credit: CDC, Wikimedia Commons

Trypanosoma cruzi parasitemia in chronic Chagas disease: Insights from hierarchical modeling

Recently Published Articles

Current Issue

Current Issue July 2022

08/04/2022

Policy Platform

World Dengue Day: A call for action

Nattachai Srisawat and colleagues describe the meeting of the International Society for Neglected Tropical Diseases and Asian Dengue Voice and Action group that brought together the collaborative efforts of healthcare care professionals, researchers, epidemiologists, environmentalists, and policy makers to coordinate international dengue control strategy at the ISNTD-ADVA World Dengue Day Forum.

Image credit: CDC, Wikimedia Commons

World Dengue Day: A call for action

08/04/2022

Research Article

Comparative dynamics of Orientia tsutsugamushi Karp versus Gilliam strains

Manutsanun Inthawong and colleagues characterize an improved intradermal rhesus macaque challenge model for scrub typhus, whereby the Gilliam strain infection is associated with higher disease severity in the rhesus macaque model than the previous Karp strain infection.

Comparative dynamics of Orientia tsutsugamushi Karp versus Gilliam strains

Image credit: Inthawong M, et al.

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PLOS Neglected Tropical Diseases | ISSN: 1935-2735 (online)