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Fifty years of struggle to control cutaneous leishmaniasis in the highest endemic county in Iran

April 29, 2022

Fifty years of struggle to control cutaneous leishmaniasis in the highest endemic county in Iran

In this longitudinal observational study to assess the impact of interventions applied between 1971 and 2020 in Bam county, Iran, Mohammadreza Aflatoonian and colleagues find that the main factors negatively impacting to cutaneous leishmaniasis control are cessation of malaria spraying activity, expansion of the city spaces, and a massive earthquake creating new breeding potentials for the vectors. 

Image credit: Aflatoonian M, et al. pntd.0010271

2021 Year in Review

Thank you to all of our authors, reviewers, and editors who helped us achieve so much last year, despite                                                      another challenging year of the COVID-19 pandemic. You can read more about the PLOS NTDs community's                                                    2021 accomplishments by clicking on the '2021' button. 

2021

04/28/2022

Review

Finding a chink in the armor: Update, limitations, and challenges toward successful antivirals against flaviviruses

Thamil Vaani Komarasamy and colleagues review the latest progress in the development of both new and repurposed direct-acting antivirals, host-targeting antivirals, and multitarget antivirals against flaviviruses, which have been evaluated both in vitro and in vivo, with an emphasis on their targets and mechanisms. Read the Review

Image credit: Cynthia Goldsmith, P.E. Rollin, USCDCP, Wikimedia Commons

Finding a chink in the armor: Update, limitations, and challenges toward successful antivirals against flaviviruses

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PLOS Neglected Tropical Diseases | ISSN: 1935-2735 (online)