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02/08/2024

Review

The importance of estimating the burden of disease from foodborne transmission of Trypanosoma cruzi

Chagas disease (ChD), caused by infection with the flagellated protozoan, Trypanosoma cruzi, has a complicated transmission cycle with many infection routes. These include vector-borne (via the triatomine (reduviid bug) vector defecating into a skin abrasion, usually following a blood meal), transplacental transmission, blood transfusion, organ transplant, laboratory accident, and foodborne transmission…

Image credit: pntd.0011898

The importance of estimating the burden of disease from foodborne transmission of Trypanosoma cruzi

Recently Published Articles

Current Issue

Current Issue February 2024

02/26/2024

Research Article

Benidipine impairs innate immunity converting sublethal to lethal infections in a murine model of spotted fever rickettsiosis

Spotted fever group rickettsiae are tick-borne obligate intracellular bacteria that infect microvascular endothelial cells. Humans and mammalian infection results in endothelial cell barrier dysfunction and increased vascular permeability. We previously demonstrated that treatment of Rickettsia parkeri-infected cells with the calcium channel blocker benidipine significantly delayed vascular barrier permeability.

Image credit: pntd.0011993

Benidipine impairs innate immunity converting sublethal to lethal infections in a murine model of spotted fever rickettsiosis

02/21/2024

Research Article

Parasites and microorganisms associated with the snakes collected for the “festa Dei serpari” in Cocullo, Italy

While in much of the Western world snakes are feared, in the small, rural, mountainous town of Cocullo, in the middle of central Italy, snakes are annually collected and celebrated in a sacro-profane ritual. Every 1st of May, Serpari (snake catchers) capture and showcase dozens of non-venomous snakes to celebrate the ritual of San Domenico...

Image credit: pntd.0011973

Parasites and microorganisms associated with the snakes collected for the “festa Dei serpari” in Cocullo, Italy

02/08/2024

Viewpoints

The use of artificial intelligence to improve mycetoma management

Mycetoma is a serious, neglected tropical disease affecting the underprivileged populations in resource-constrained communities of the rural tropical and subtropical regions. It predominately affects individuals of low visibility and voice and continues to hinder and burden the poor, remote communities. Furthermore, in endemic areas, the medical...

The use of artificial intelligence to improve mycetoma management

Image credit: CDC

02/26/2024

Research Article

Needs assessment of a pythiosis continuing professional development program

Pythiosis is a rare disease with high mortality, with over 94% of cases reported from Thailand and India. Prompt diagnosis and surgery improves patient outcomes. Therefore, continuing professional development (CPD) is essential for early recognition. However, a needs assessment related to a pythiosis CPD program has not been performed…

Needs assessment of a pythiosis continuing professional development program

Image credit: pntd.0012004

02/20/2024

Research Article

Conducting active screening for human African trypanosomiasis with rapid diagnostic tests: The Guinean experience (2016–2021)

Strategies to detect Human African Trypanosomiasis (HAT) cases rely on serological screening of populations exposed to trypanosomes. In Guinea, mass medical screening surveys performed with the Card Agglutination Test for Trypanosomiasis have been progressively replaced by door-to-door approaches using Rapid Diagnostic Tests…

Conducting active screening for human African trypanosomiasis with rapid diagnostic tests: The Guinean experience (2016–2021)

Image credit: pntd.0011985

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PLOS Neglected Tropical Diseases | ISSN: 1935-2735 (online)