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Table of Contents

November 2010

Estimates of global health indicators—which give insight into death and disease rates, document advances in development, and help policymakers monitor progress—are absolutely essential for improving global health. Estimates, however, are always imperfect and are sometimes fiercely debated. Recently, new players from academia have entered the game of global health estimation, once the chief domain of United Nations agencies such as WHO. This has created some controversy but also an opportunity to reflect. In November 2010, PLoS Medicine published a cluster of six articles from a series of experts that provide insights and opinion on what estimates mean for global health and how to move forward with better data, measurement, coordination, and leadership. The cluster includes the perspectives of WHO, the Institute for Health Metrics and Evaluation (IHME), and stakeholders from low- and middle-income countries, as well as the PLoS Medicine Editors.

Image Credit: D. Sharon Pruitt


Can We Count on Global Health Estimates?

The PLoS Medicine Editors


WHO and Global Health Monitoring: The Way Forward

J. Ties Boerma, Colin Mathers, Carla Abou-Zahr

Production and Analysis of Health Indicators: The Role of Academia

Christopher J. L. Murray, Alan D. Lopez

A Call for Responsible Estimation of Global Health

Wendy J. Graham, Sam Adjei

Policy Forums

Hygiene, Sanitation, and Water: Forgotten Foundations of Health

Jamie Bartram, Sandy Cairncross

Water Supply and Health

Paul R. Hunter, Alan M. MacDonald, Richard C. Carter

Sanitation and Health

Duncan Mara, Jon Lane, Beth Scott, David Trouba

Hygiene, Sanitation, and Water: What Needs to Be Done?

Sandy Cairncross, Jamie Bartram, Oliver Cumming, Clarissa Brocklehurst

Combining Domestic and Foreign Investment to Expand Tuberculosis Control in China

Zhong-wei Jia, Shi-ming Cheng, Zhi-jun Li, Xin Du, Fei Huang, Xiao-wei Jia, Peng Kong, Yun-xi Liu, Wei Chen, Wei Wang, Christopher Dye

Defining Research to Improve Health Systems

Jan H. F. Remme, Taghreed Adam, Francisco Becerra-Posada, Catherine D'Arcangues, Michael Devlin, Charles Gardner, Abdul Ghaffar, Joachim Hombach, Jane F. K. Kengeya, Anthony Mbewu, Michael T. Mbizvo, Zafar Mirza, Tikki Pang, Robert G. Ridley, Fabio Zicker, Robert F. Terry

Research Articles

Efficacy of Oseltamivir-Zanamivir Combination Compared to Each Monotherapy for Seasonal Influenza: A Randomized Placebo-Controlled Trial

Xavier Duval, Sylvie van der Werf, Thierry Blanchon, Anne Mosnier, Maude Bouscambert-Duchamp, Annick Tibi, Vincent Enouf, Cécile Charlois-Ou, Corine Vincent, Laurent Andreoletti, Florence Tubach, Bruno Lina, France Mentré, Catherine Leport, and the Bivir Study Group

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