June 6, 2022
Image credit: Nela Klimova
06/23/2022
Opinion
In this Opinion, members of the One Health High-Level Expert Panel present their working definition of “One Health” and the fundamental principles it is based upon.
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Current Issue July 2022
06/16/2022
Pearls
In this Pearls article, Heath & Dembowski discuss the studies that defined the 4 HSV-1 gene classes and examine how viral DNA replication may facilitate a switch to regulate γ (γ1/γ2) gene transcription
Image credit: Ed Uthman, flickr
06/09/2022
Pearls
In this Pearls article, Parthasarathy & Fehr discuss PARP14, a MARylating enzyme that is implicated in a range of processes from tumorigenesis to DNA repair.
Image credit: Public Health Image Library from the Centers for Disease Control and Prevention
05/26/2022
Research Article
Littlefield et al. look for mechanisms behind long-term lung dysfunction following COVID-19 infection. They find that T cells specific for SARS-CoV-2 are elevated in the blood of those with pulmonary PASC and are associated with increased IL-6, a cytokine strongly associated with COVID-19 severity, and decreased lung function.
Image credit: Fusion Medical Animation, Unsplash
05/23/2022
Research Article
Rudolph et al. present a novel method to film the spatiotemporal dynamics of the Yersinia T3SS translocon by inserting a small peptide tag into the minor translocon protein YopD that can be bound with high affinity by a corresponding fluorophore-labeled nanobody during the infection process.
Image credit: Maren Rudolph and Martin Aepfelbacher
05/27/2022
Research Article
Godlee et al. show that Salmonella effector SteD integrates into membranes of the early secretory pathway through a two-step recruitment and integration mechanism. SteD then behaves like a transmembrane cargo protein and hijacks a post-Golgi vesicular trafficking pathway to reach MHCII compartments.
Image credit: ppat.1010252
05/19/2022
Research Article
From Sandrine Belouzard, Arnaud Machelart, and colleagues.
Image credit: Viktor Forgacs, Unsplash
05/25/2022
Research Article
From Xinyao Liu and colleagues.
Image credit: ppat.1010534
05/27/2022
Research Article
From Lauren M. Hemara, Jay Jayaraman, and colleagues.
Image credit: ppat.1010542
05/19/2022
Research Article
From Nichola J. Hill and colleagues.
Image credit: ppat.1010062
Qi-Yue Yang, Yong-Le Yang, and colleagues
Frideborg Bradley and colleagues
Jodie A. Schiffer & Stephanie V. Stumbur and colleagues
B. Karina Montero and colleagues
Andrea Martinez Aguirre and colleagues
Koszalka and colleagues
Ander and colleagues
Parks and colleagues
Shunmugam, Arnold, and colleagues
Mouat and Horwitz
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