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The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele: MICA*008, to evade NK cell-mediated killing

May 3, 2021

The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele: MICA*008, to evade NK cell-mediated killing

A new research article from Einat Seidel, Liat Dassa and colleagues

Image credit: ppat.1008807

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Current Issue April 2021

04/22/2021

review

Actives from MMV Open Access Boxes? A suggested way forward

The release of “Open Access Boxes” is an initiative launched by Medicines for Malaria Venture (MMV) in collaboration with its partners to catalyze new drug discovery in neglected diseases. Here, Kirandeep Samby and colleagues present guidelines on how to move actives beyond the hit identification stage, to help in capacity strengthening and enable a greater impact of the initiative.

Image credit: ppat.1009442

Actives from MMV Open Access Boxes? A suggested way forward

04/29/2021

RESEARCH ARTICLE

3-D model of EBV infection in the nasopharynx

Ziegler et al create a primary nasopharyngeal three-dimensional air-liquid interface cell culture model of the pseudostratified epithelium reveals differential donor- and cell type-specific susceptibility to Epstein-Barr virus infection.

3-D model of EBV infection in the nasopharynx

Image credit: ppat.1009041

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