Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria
The bacterium Clostridium difficile, which is responsible for the majority of antibiotic-associated diarrhea outbreaks worldwide, produces a unique compound called p-cresol to gain a competitive advantage over natural protective gut bacteria. The findings were reported by Dawson and colleagues in this PLOS Pathogens Featured Research article.
Image credit: Passmore IJ, et al. (2018)