August 5, 2019
Image credit: Cui Z, et al. (2019)
08/08/2019
Featured Research
Bullard et al.'s findings provide substantial new information about specific targets of MHV68 miRNAs and shed important light on likely conserved functions of gammaherpesvirus miRNAs.
Image credit: Bullard WL, et al. (2019)
Current Issue July 2019
08/08/2019
Featured Research
Qiao and Luo's findings demonstrate that human apoE promotes HBV infection and production. The authors speculate that apoE may also play a role in persistent HBV infection by evading host immune response similar to its role in the HCV life cycle and pathogenesis. Inhibitors interfering with apoE biogenesis, secretion, and/or binding to receptors may serve as antivirals for elimination of chronic HBV infection.
Image credit: Qiao L, Luo GG (2019)
08/08/2019
Pearls
Butt and Epplein discuss how there is growing evidence for H. pylori infection increasing CRC risk. A causal relationship and the mechanism behind this bacterium potentially acting abroad from its natural habitat, the stomach, however, still need to be clarified. Independent of a causal relationship, the knowledge of the association of H. pylori and CRC risk could help to define more rigid CRC screening programs for H. pylori–positive individuals.
Image credit: Butt J, Epplein M (2019)
08/08/2019
Pearls
Here, in this Pearl, Chiang et al. provide a brief overview of what is known and what is new in phage transduction. They will also discuss noncanonical examples of transduction in which pathogenicity islands exploit phages for horizontal gene transfer.
Image credit: Chiang YN, Penadés JR, Chen J (2019)
08/06/2019
Research Article
Madigan et al. identify a network of host proteins involving RNF121, p97 and the DNA damage machinery as potent factors regulating AAV genome transcription. Their study sheds light on an understudied aspect of AAV biology with implications for gene therapy.
Image credit: Madigan VJ, et al. (2019)
08/05/2019
Research Article
Du Pont et al.'s study recommend the P-XD:L protein-protein interface as premier target for directed drug discovery against emerging and re-emerging paramyxoviruses.
Image credit: Du Pont V, et al. (2019)
08/05/2019
Research Article
Image credit: Fan Y-C, et al. (2019)
08/05/2019
Research Article
Image credit: Lingemann M, et al. (2019)
08/05/2019
Research Article
Image credit: Horova V, et al. (2019)
08/05/2019
Research Article
Image credit: Singh S, et al. (2019)
Connect with Us