September 16, 2024
Image credit: ppat.1012555
09/16/2024
research article
Determining the structure of EtpA with protective and non-protective antibodies targeting two domains, identifying key regions for blood-group A antigen recognition, and revealing the mechanism of antibody-based protection.
Image credit: ppat.1012241
Current Issue September 2024
09/16/2024
research article
Offering insights into the function and potential inhibition of ChiA and ChiB causing necrotic enteritis. The crystal structures of ChiA and ChiB reveal distinct substrate preferences.
Image credit: ppat.1012560
09/16/2024
research article
Using scRNA-seq to study microglial and CAM populations in rhesus macaques during acute SIV infection, identified gene signatures and two myeloid cell clusters associated with neurodegenerative disorders.
Image credit: ppat.1012168
09/09/2024
research article
New determinants of caspofungin susceptibility illuminate the evolution of drug target and non-drug target mutations reducing echinocandin efficacy in patients colonized with C. glabrata.
Image credit: ppat.1012521
09/11/2024
research article
Unexpected metabolic dimension of prion infections revealed pointing to a potential role for GLUL dysregulation in the glutamate/glutamine metabolism in prion-affected skeletal muscle.
Image credit: ppat.1012552
09/09/2024
research article
Leishmania mexicana induces NLRP1- and caspase-1-dependent Gasdermin D (GSDMD)-mediated pyroptosis in neutrophils, a process critical to control the parasite-induced pathology.
Image credit: ppat.1012527
08/08/2024
research article
Development of a novel prime/boost vaccination strategy consisting of an initial intramuscular immunization ...
Image credit: ppat.1012393
08/08/2024
research article
A novel viral diversity-based method to screen for interactions across the viral genome systematically ...
Image credit: ppat.1012385
08/08/2024
review
Recent progress in understanding the compositional and functional diversity of gut mycobiome signatures across different liver diseases.
Image credit: ppat.1012377
Brittany Seibert, C. Joaquín Cáceres, and colleagues
Qi-Yue Yang, Yong-Le Yang, and colleagues
Frideborg Bradley and colleagues
Jodie A. Schiffer & Stephanie V. Stumbur and colleagues
B. Karina Montero and colleagues
Hakimi et al.
Jansen et al.
Verburg et al.
Sheedlo et al.
Jafarzadeh et al.
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