Structural determination of the complement inhibitory domain of Borrelia burgdorferi BBK32 provides insight into classical pathway complement evasion by lyme disease spirochetes

CD8+ T cells play an important role in controlling of HIV and SIV infections. However, these cells are largely excluded from B cell follicles .Li et al.'s studies suggest that a paucity of SIV-specific CD8+ T cells in follicles and complete absence within GCs during early infection may set the stage for the establishment of persistent chronic infection. 

Morgan et al.'s study suggests that many bacterial virulence functions and biofilm formation are not required for fitness of infecting bacteria in chronic wounds. Rather, functions that mitigate stresses associated with high-density bacterial growth are critical for infection. 

Portet et al. use a combination of molecular and phenotypic approaches to compare the effect of infection in various sympatric and allopatric evolutionary contexts, allowing us to better understand the mechanisms of host-parasite local adaptation.