April 8, 2021
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04/01/2021
Pearls
In this Pearls article, Liwen Deng & Isaac M. Chiu review recent studies that highlight how bacteria, fungi & viruses interact with nociceptors during infection to modulate pain and cough and touch upon microbes that silence pain.
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Current Issue March 2021
04/01/2021
Review
Beck & Ho review our current understanding of the transport mechanisms acting at the malaria parasite vacuole during the blood and liver-stages of development with a particular focus on recent advances in our understanding of effector protein translocation into the host cell by the Plasmodium Translocon of EXported proteins (PTEX) and small molecule transport by the PTEX membrane-spanning pore EXP2.
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04/01/2021
Pearls
Prototheca and their relatives represent a fascinating but poorly understood class of pathogens. In this Pearls article, Shave, Millyard & May discuss Prototheca algae and how it is capable of casuing disease in mammals.
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04/07/2021
Research Article
Kumar, Deshpande and colleagues study the structural and immunogenic properties of an HIV-1 clade C Env trimer.
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04/07/2021
Research Article
Valesano et al use high depth of coverage sequencing to identify within-host genetic variants in 325 specimens from hospitalized COVID-19 patients and infected employees at a single medical center, showing that there are relatively few genetic variants present in any given infection, and variants do not tend to accumulate in people over time.
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04/02/2021
Research Article
Yunuen Avalos-Padilla and colleagues study underlying molecular mechanisms of malaria pathogenesis and demonstrate that ESCRT-III P. falciparum proteins participate in extracellular vesicle production in parasitized red blood cells.
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03/26/2021
Research Article
Luangtrakul et al find that cytotoxicity of Vibrio parahaemolyticus AHPND toxin on shrimp hemocytes, a newly identified target tissue, involves binding of toxin to aminopeptidase N1 receptor.
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03/31/2021
Research Article
Naveen Parmar et al find that Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection.
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03/26/2021
Research Article
Schilling et al investigate functional regulation of the structure-specific endonuclease FEN1 by the human cytomegalovirus protein IE1.
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03/31/2021
Research Article
Baeder & Rodríguez-Rojas et al discover that bacteria primed by antimicrobial peptides develop tolerance and persist.
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A Pearls article by Ludington and Ja
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