January 30, 2020
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01/30/2020
Pearls
In this PLOS Pathogens Pearls article, Abimbola O. Kolawole and Christiane E. Wobus highlight how gastrointestinal organoids have provided new insights into the biology of human enteric viruses and the potential of this technology for advancing the field.
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Current Issue January 2020
01/30/2020
Review
This Review article by Netea and colleagues proposes several scenarios that may be encountered when terrestrial microorganisms come into contact with new planetary environments and explore how this may affect their pathogenic potential.
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01/30/2020
Pearls
Satish Kumar Rajasekharan and Jintae Lee explain methuosis cell death in nematodes in this Pearls article and discuss this vacuole formation as a potential mechanism for anthelmintics against medically important mammalian-parasitic nematodes.
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01/27/2020
Research Article
Dick, Schur and colleagues use in vitro assembly, cryo-electron tomography and subtomogram averaging, molecular dynamics simulations and mutational analyses to characterise the structure of the HIV-related lentivirus equine infectious anemia virus (EIAV). They find that IP6 is an assembly cofactor of EIAV.
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02/06/2020
Research Article
In this study, Bergren and colleagues discuss the reduction in incidence and transmission activity of WEEV and identify six amino acid substitutions that appeared to increase fitness in avian hosts and/or mosquito vectors, suggesting that ecological factors likely explain the reduction in WEEV activity.
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02/05/2020
Research Article
Pankau and colleagues study sequences of the HIV strains that circulate throughout infection and those that persist in reservoir cells during antiretroviral therapy (ART). They find that many HIV sequences enter the reservoir near the time of ART initiation and so strategies to reduce reservoir size should focus prior to ART.
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01/29/2020
Research Article
Scherer and colleagues elucidate mechanisms governing axonal sorting in enveloped alpha herpesvirus capsids and give insight into the composition of neuronal transport systems.
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01/30/2020
Research Article
Vendele and colleagues discuss immune receptor maps of fungal walls of in vitro grown cells.
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01/30/2020
Research Article
Darling and colleagues identify a new molecule critical for cerebral malaria in mice and provide a basis for exploring this receptor as a novel therapeutic target in human cerebral malaria in the future.
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02/04/2020
Research Article
Woerman and colleagues find that α-synuclein prion spreading precedes the formation of neuropathological lesions yielding new insights into the progression of MSA.
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Harris and colleagues.
A PLOS Pathogens Opinion article by Dheilly and colleagues.
Cheng, Chen, Huang, and colleagues
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