June 22, 2022
Image credit: Jennifer McDonald
06/24/2022
Review
In this Review, Files & Tacke et al. review the literature surrounding the C-C chemokine receptor type 2 (CCR2) and CCR5 pathways, their proposed role in COVID-19, and the potential role of antagonist cenicriviroc as a treatment option to improve disease outcomes.
Image credit: Elena Mozhvilo, Unsplash
Current Issue July 2022
06/30/2022
Pearls
In this Pearls article, Caughey et al. note recent advances revealing the structures of highly pathogenic brain-derived prions, and highlight how these new prion structures have begun to address fundamental, long-standing questions in prion biology.
Image credit: ppat.1010594
06/30/2022
Pearls
In this Pearls article, Whitford and Cliffe highlight recent developments and incorporate new questions that will ultimately help understand how HSV latency occurs in neurons and how the epigenetic structure of the viral genome may ultimately impact clinical HSV-associated disease.
Image credit: ppat.1010587
06/03/2022
Research Article
Eyran et al. follow the persistence of antibodies recovered COVID-19 patients and find evidence suggesting that there are fundamental differences between the mechanisms of activation of the adaptive arm of the immune response following vaccine and natural infection.
Image credit: CDC Public Health Image Library
06/13/2022
Research Article
Yang et al. explain how bile acids acts on epithelial cells to enhance SADS-CoV replication by inducing caveolae-mediated endocytosis and endosomal acidification, altering the dynamics of viral trafficking through the cellular endosomal/lysosomal system.
Image credit: ppat.1010620
06/10/2022
Research Article
Paton et al. show that insecticide-resistance mechanisms in highly resistant Anopheles populations don't interfere with the transmission blocking activity of tarsal exposure to the antimalarial atovaquone, and that mosquito-targeted antimalarial exposure can block transmission of parasites resistant to the drug artemisinin.
Image credit: ppat.1010609
06/14/2022
Research Article
From Wakana Saso and colleagues.
Image credit: Fusion Medical Animation, Unsplash
06/13/2022
Research Article
From Roz Laing and colleagues.
Image credit: CSIRO
06/02/2022
Research Article
From Ryotaro Nouda and colleagues.
Image credit: ppat.1010553
06/08/2022
Research Article
From Bradley E. Hiller and colleagues.
Image credit: Bradley E. Hiller
Qi-Yue Yang, Yong-Le Yang, and colleagues
Frideborg Bradley and colleagues
Jodie A. Schiffer & Stephanie V. Stumbur and colleagues
B. Karina Montero and colleagues
Andrea Martinez Aguirre and colleagues
Silva et al.
Koszalka and colleagues
Ander and colleagues
Parks and colleagues
Shunmugam, Arnold, and colleagues
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