The family Paramyxoviridae includes several important human and animal pathogens such as mumps virus (MuV) and measles virus (MeV). Katoh et al. identify the R2TP complex as a novel host factor regulating paramyxovirus RNA synthesis. The authors' findings support a novel regulation mechanism of paramyxovirus RNA synthesis that is directly relevant to its biology and life cycle.
Image credit: Katoh H, et al. (2019)