October 10, 2018
Image credit: Leopold Wager CM, etal. (2018)
10/11/2018
Pearl
Carbohydrate recognition is fundamental to a wide variety of interkingdom interactions. Jonathan Dworkin illuminates how promiscuous activation could occur when a structurally similar but physiologically inappropriate ligand binds and activates an incorrect LysM, and its implications for immune pathologies.
Image credit: Dworkin J (2018)
Current Issue September 2018
10/11/2018
Research Article
Ankri et al. demonstrate that E. coli malate dehydrogenase (EcMDH) and its product, oxaloacetate, are key elements of E. coli-mediated resistance of E. histolytica to oxidative stress and that oxaloacetate helps the parasite survive in the large intestine of its human host. .
Image credit: Shaulov Y, et al (2018)
10/11/2018
research article
Understanding how clinical phenotype is affected by genetic variation at the molecular level is often lacking yet critical for any insight into immunity and disease.McLauchlan et al. suggest that human IFNL4 evolution places humans at a disadvantage when infected with pathogens such as HCV.
Image credit: Bamford CGG, et al. (2018)
10/11/2018
research article
CD8+ lymphocytes play an important role in suppressing in vivo viral replication in HIV infection. By mathematically modeling data from a recent CD8 depletion experiment done in antiretroviral (ART) treated animals, Perelson et al.'s results reveals a detailed dynamic role of CD8+ lymphocytes in controlling viral infection, and provides a unified explanation for CD8 depletion experimental data.
Image credit: Cao Y., et al. (2018)
10/11/2018
research article
Pneumococcal biofilms occur in chronic otitis media, chronic rhinosinusitis, and nasopharyngeal colonization.These biofilms are an important component of pneumococcal epidemiology, particularly in influencing transmission. Hiller et al. introduces a colonization factor and reveals a molecular link between competence and biofilm development.
Image credit: Aggarwal SD, (2018)
10/08/2018
RESEARCH article
Buseyne et al's findings suggest that neutralizing antibodies raised against zoonotic SFV target epitopes support their potential role in restricting the spread of SFV.
Image credit: Lambert C, et al. (2018)
10/04/2018
research article
Cai et al.
Image credit: Jiang K, et al. (2018)
09/28/2018
Research Article
Image credit: Ravichandran S, et al. (2018)
10/01/2018
research article
Image credit: Jondle CN, et al. (2018)
09/28/2018
research article
Image credit: Wang MK-M, et al. (2018)
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