03/25/2021
Pearls
Sieve analysis to understand how SARS-CoV-2 diversity can impact vaccine protection
Morgane Rolland and Peter Gilbert describe how sieve analyses compare SARS-CoV-2 sequences from breakthrough infections in vaccine recipients to the sequences found in placebo recipients to understand if vaccination fails to protect against specific genetic variants, characterize the potential impact of vaccines on SARS-CoV-2 evolution, and help design next-generation vaccines.
Image credit: ppat.1009406
Connect with Us