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PLOS Pathogens Invites Antifungal Immunity Research 

Speaking of Medicine Blog

Call for Papers

02/21/2019

Review

Casting a wider net: Immunosurveillance by nonclassical MHC molecules

D'Souza et al. summarize salient points presented at a recent workshop, “Immune Surveillance by Non-classical MHC Molecules: Improving Diversity for Antigens,” sponsored by the National Institute of Allergy and Infectious Diseases regarding the basic immunobiology of unconventional T cells, recent advances in methodologies to measure unconventional T-cell activity in diseases, and approaches to harness their considerable clinical potential.

Image credit: D’Souza MP, et al. (2019)

Casting a wider net: Immunosurveillance by nonclassical MHC molecules

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Current Issue

Current Issue January 2019

02/21/2019

Pearls

The founder hypothesis: A basis for microbiota resistance, diversity in taxa carriage, and colonization resistance against pathogens

 Our skin and mucosal surfaces are colonized by diverse microbial communities, collectively known as the microbiota. Litvak & Bäumler argue that investment in research on the mechanistic underpinnings of priority effects will greatly enhance our understanding of how host-associated microbial communities function during health and disease and usher in an era of mechanistic microbiota research.

Image credit: Litvak Y, et al. (2019)

The founder hypothesis: A basis for microbiota resistance, diversity in taxa carriage, and colonization resistance against pathogens

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