December 1, 2022
Image credit: Jibin Sadasivan
12/02/2022
Opinion
In this Opinion, Boon et al. highlight evidence showing that the combined analysis from multiple groups using different isolates of the BA.1 Omicron variant demonstrate that BA.1 has reduced airborne transmission efficiency in Syrian hamsters compared to prior variants of SARS-CoV-2.
Image credit: US CDC
Current Issue December 2022
11/17/2022
Review
In this Review, Vojtechova et al. discuss the available evidence for the involvement of infections in Alzheimer's disease. They argue there is no unique “Alzheimer’s germ,” instead, AD is a general reaction of the CNS to chronic infections, in the milieu of an aged immune system.
Image credit: ppat.1010929
10/13/2022
Review
In this Review, O’Shaughnessy et al. outline advances in our understanding of the function and biochemistry of MAPK signaling in apicomplexan parasites. They highlight what few regulatory relationships have been established to date, and discuss the challenges to the field in elucidating the complete MAPK signaling networks in these parasites.
Image credit: ppat.1010849
11/30/2022
Research Article
Hurst et al. outline an important interaction between the HA capsule and neutrophils in the establishment of acute upper respiratory and skin infections by S. pyogenes.
Image credit: ppat.1011013
11/16/2022
Research Article
Liang et al. find that BmSUH, a midgut microvilli protein, is required for the efficient oral infection of BmNPV. Their research suggests that BmSUH mediates the entry of occlusion-derived virions into the midgut epithelia by interacting with per os infectivity factors.
Image credit: ppat.1010938
11/30/2022
Research Article
Tu et al. report the mediator of IRF3 activation (MITA) undergoes DDOST-mediated N-glycosylation in the endoplasmic reticulum upon DNA viral infection.
Image credit: ppat.1010989
11/18/2022
Research Article
From Philipp-Albert Sänger and colleagues.
Image credit: ppat.1010991
11/14/2022
Research Article
From Yuanwei Zhang and colleagues.
Image credit: ppat.1010976
11/17/2022
Research Article
From Chandra Ramakrishnan and colleagues.
Image credit: ppat.1010955
11/07/2022
Research Article
From Forrest Hoyt and colleagues.
Image credit: ppat.1010947
Brittany Seibert, C. Joaquín Cáceres, and colleagues
Qi-Yue Yang, Yong-Le Yang, and colleagues
Frideborg Bradley and colleagues
Jodie A. Schiffer & Stephanie V. Stumbur and colleagues
B. Karina Montero and colleagues
Hakimi et al.
Jansen et al.
Verburg et al.
Sheedlo et al.
Jafarzadeh et al.
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