September 3, 2019
Image credit: Lenarčič T, et al. (2019)
09/05/2019
Featured Research
In this week's featured research, Mouser et al. have shown that SEA parasite antigens and more specifically rω-1 can modulate HIV-1 infectivity with the potential to influence disease course in co-infected individuals.
Image credit: Mouser EE, et al. (2019)
Current Issue August 2019
09/05/2019
Pearls
Kumar and Tolia describe the structural and functional details of Plasmodium-specific invasion proteins involved in 1) traversal, 2) hepatocyte invasion, and 3) erythrocyte invasion. The current review focusses on the most virulent human malaria parasites, P. falciparum and P. vivax. Additional components of the invasion machinery are also excluded from the current study as they have been extensively reviewed elsewhere.
Image credit: Kumar H, Tolia NH (2019)
09/05/2019
Opinion
Here, Jia and Jeon summarize recent studies describing the influence of the gut microbiome on liver cancer pathogenesis through BA-mediated regulation of the liver immune system. The findings summarized are expected to guide the development of strategies aimed at liver cancer prevention and clinical therapy by highlighting the gut microbiome as a therapeutic target.
Image credit: Jia B, Jeon CO (2019)
09/05/2019
Research Article
Gasiorowski et al. show that HP0851, renamed HupA, is the major undecaprenyl pyrophosphate (C55-PP) phosphatase (UppP) and the major phosphatidylglycerol phosphate phosphatase (PGPase).
Image credit: Gasiorowski E, et al. (2019)
09/03/2019
Research Article
Singh et al.'s data suggest a role for KSHV-encoded LANA in replication of infected cells, and provides a mechanism for sustained replication of both cellular and viral DNA in hypoxia.
Image credit: Singh RK, et al. (2019)
09/03/2019
Research Article
Sacks et al.'s data highlight the complex interdependencies between high levels of SHM and breadth, as mutations that neutralize autologous viruses may limit heterologous breadth.
Image credit: Sacks D, et al. (2019)
08/30/2019
Research Article
Image credit: Perov S, et al. (2019)
08/29/2019
Research Article
Image credit: Rodríguez-Mora S, et al. (2019)
08/29/2019
Research Article
Image credit: Young AR, et al. (2019)
08/28/2019
Research Article
Image credit: Zhang J, et al. (2019)
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