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Publishing Dual Use Research of Concern: A Case Study

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Current Issue September 2018

10/11/2018

research article

CD8+ lymphocyte control of SIV infection during antiretroviral therapy

CD8+ lymphocytes play an important role in suppressing in vivo viral replication in HIV infection. By mathematically modeling data from a recent CD8 depletion experiment done in antiretroviral (ART) treated animals, Perelson et al.'s results reveals a detailed dynamic role of CD8+ lymphocytes in controlling viral infection, and provides a unified explanation for CD8 depletion experimental data. 

CD8+ lymphocyte control of SIV infection during antiretroviral therapy

Image credit: Cao Y., et al. (2018)

10/11/2018

research article

Function of BriC peptide in the pneumococcal competence and virulence portfolio

Pneumococcal biofilms occur in chronic otitis media, chronic rhinosinusitis, and nasopharyngeal colonization.These biofilms are an important component of pneumococcal epidemiology, particularly in influencing transmission. Hiller et al. introduces a colonization factor and reveals a molecular link between competence and biofilm development.

Function of BriC peptide in the pneumococcal competence and virulence portfolio

Image credit: Aggarwal SD, (2018)

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