February 17, 2023
Image credit: Hawaii Dept. of Health
03/30/2023
Research Article
Trypanosoma brucei spp. develop into mammalian-infectious metacyclic trypomastigotes inside tsetse flies.
Image credit: Oregon State University
Current Issue April 2023
03/27/2023
Research Article
Mutations continue to accumulate within the SARS-CoV-2 genome, and the ongoing epidemic has shown no signs of ending. In this study, we identified mutations resistant to remdesivir, which is widely administered to SARS-CoV-2-infected patients,and discuss the cause of resistance.
Image credit: Koto Feja
03/30/2023
Research Article
Mosquito transmission of dengue viruses to humans starts with infection of skin resident cells at the biting site. There is great interest in identifying transmission-enhancing factors in mosquito saliva in order to counteract them.
Image credit: Yogesh Padamka
04/03/2023
Research Article
More than a hundred thousand dengue cases are diagnosed in India annually, and about half of the country’s population carries dengue virus-specific antibodies. Dengue propagates and adapts to the selection pressures imposed by a multitude of factors that can lead to the emergence of new variants. Yet, there has been no systematic analysis of the evolution of the dengue virus in the country.
Image credit: Roy et al
04/03/2023
Research Article
Cereal yellow dwarf virus (CYDV-RPV) encodes a P0 protein that functions as a viral suppressor of RNA silencing (VSR). In this study, comparison of the P0 sequences of CYDV-RPV isolates and mutational analysis identified a single C-terminal amino acid that influenced P0 RNA-silencing suppressor activity.
Image credit: Amit Lahav
04/06/2023
Pearls
Eukaryotes are endowed with sophisticated innate immune systems to recognize non-self and halt pathogen proliferation. Activation of cell death at the site of attempted pathogen ingress is a common strategy used by plants and animals to restrict pathogen proliferation and trigger immune responses in the surrounding tissues. As such, immunogenic cell death shares several traits in plants and animals
Image credit: National Cancer Institute
02/23/2023
Review
This review sought to better understand the biogenesis of extracellular vesicles in protozoan parasites as a means to inform therapeutic interventions.
Image credit: Camacho et al
02/23/2023
Pearls
This review from Dr. Liliane Mukaremera aims to assess new insights into the unique attributes about the Cryptococcus cell wall in relation to the pathogenic lifestyle of these important pathogens
Image credit: Wikipedia/Nephron
02/14/2023
Research Article
The impacts of transposable elements, engines of evolution, are multifaceted but vulnerable to pathogens, who mutate or silence them...
Image credit: Irena Carpaccio
02/13/2023
Research Article
This study identified the pivotal role of peritrophic matrix-driven intestinal homeostasis in dengue and Zika infection.
Image credit: Talyuli et al
Brittany Seibert, C. Joaquín Cáceres, and colleagues
Qi-Yue Yang, Yong-Le Yang, and colleagues
Frideborg Bradley and colleagues
Jodie A. Schiffer & Stephanie V. Stumbur and colleagues
B. Karina Montero and colleagues
Hakimi et al.
Jansen et al.
Verburg et al.
Sheedlo et al.
Jafarzadeh et al.
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