May 28, 2021
Image credit: Johnny R. Ramroop
06/10/2021
Pearls
Brackney, LaReau & Smith discuss recent work highlighting the impact of multiple blood meals on arbovirus dissemination and transmission, malaria parasite adaptation to its mosquito vector, and influence on Leishmania parasite development and transmission.
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Current Issue May 2021
06/10/2021
Pearls
In this Pearls article, Sarute & Ross describe New World arenaviruses as neglected hemorrhagic fever viruses, discuss how they enter cells and why we should continue to study this group of viruses.
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06/03/2021
Opinion
Colella and colleagues highlight a novel adaptation of Project ECHO’s virtual community of practice model: Museums and Emerging Pathogens in the Americas (MEPA). MEPA is a virtual network aimed at fostering communication, coordination, and collaborative problem-solving among pathogen researchers, public health officials, and biorepositories in the Americas.
Image credit: ppat.1009583
06/07/2021
Research Article
Hirotsu & Omata investigate novel emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages in Japan that harbor variants in the spike protein receptor-binding domain (RBD). Data indicates that emergent variants are dominated by the natural selection and need to be monitored by genomic epidemiological research.
Image credit: ppat.1009619
06/09/2021
RESEARCH ARTICLE
Yang, Weiss and colleagues develop ‘paratransgenic’ flies (which house genetically modified bacteria) which present impaired digestive processes and are highly susceptible to infection with trypanosomes.
Image credit: Flcikr user Judy Gallagher
06/10/2021
Research Article
Zhang and colleagues find that NEDD4 is acetylated at a conserved Lys667 mediated by the acetyltransferase P300 which drives ebolavirus VP40 egress process.
Image credit: ppat.1009616
06/10/2021
Research Article
Nakane, Murata & Kenri et al study the molecular ruler of the attachment organelle in Mycoplasma pneumoniae.
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06/09/2021
Research Article
Soldan et al show that EBV+ B-cells can undergo an epigenetic switch conferring a neuroinvasive phenotype with upregulation of SPP1/Osteopontin, which when blocked reduces CNS penetrance.
Image credit: ppat.1009618
06/09/2021
Research Article
Brown et al conduct a single cell analysis of host response to helminth infection, revealing the clonal breadth, heterogeneity, and tissue-specific programming of the responding CD4+ T cell repertoire.
Image credit: ppat.1009602
06/04/2021
Research Article
Cai and colleagues characterize the structure and genetic features of HIV-1 inhibitory antibodies from vaccinated monkeys as a model for human vaccination.
Image credit: ppat.1009624
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