February 25, 2021
Image credit: Camille V. Chagneau
02/25/2021
Review
Lei Deng and colleagues review recent findings on the potential interactions between Blastocystis and the gut microbiota communities and its roles in regulating host immune responses.
Image credit: ppat.1009253
Current Issue February 2021
02/25/2021
Pearls
In this Pearls article, Salvato and colleagues outline the prerequisites for starting a metaproteomics study and a general workflow for studying and analyzing microbiome interactions, as well as commenting on accessibility for the scientific community.
Image credit: ppat.1009245
02/25/2021
Review
Shanshan Zhao and Yi Li summarize the current understanding of recent advances for the classical defense hormones salicylic acid, jasmonic acid, and ethylene, as well as the roles of abscisic acid, auxin, gibberellic acid, cytokinins, and brassinosteroids in modulating plant–virus interactions.
Image credit: ppat.1009242
02/25/2021
Research Article
Gordon Y. C. Cheung and colleagues examine the role of virulence and quorum-sensing regulation in mouse and rabbit models of sepsis caused by methicillin-resistant S. aureus (MRSA). While sepsis has traditionally been attributed to host factors, this work highlights a key role of the invading pathogen and its virulence mechanisms.
Image credit: NIAID
02/25/2021
Research Article
Sonali Das and colleagues highlight the role of BRD4-depdendent super enhancers in orchestrating persistent transcription of macrophage miR146a-5p which in turn promotes M2 polarization during L. donovani infection.
Image credit: ppat.1009343
02/24/2021
Research Article
Yuebiao Feng, Lu Chen and colleagues show that rapamycin, an inhibitor of the TOR pathway, effectively suppresses Plasmodium berghei infection in Anopheles stephensi.
Image credit: Pixnio user Dr. William Collins, USCDCP
02/25/2021
Research Article
Battu et al find that an aspartyl protease-mediated cleavage regulates structure and function of a flavodoxin-like protein and aids oxidative stress survival.
Image credit: ppat.3009355
02/23/2021
Research Article
Fibriansah et al show that antibody affinity versus dengue morphology influences neutralization of the virus.
Image credit: ppat.1009331
02/22/2021
Research Article
Chowdhury et al show that a diffusible signal factor known to be a potent repressor of Salmonella invasion, is present in the murine large intestine.
Image credit: NIAID
02/23/2021
Research Article
This study from Cox & Sourimant et al demonstrates that therapeutic targeting of measles virus polymerase with ERDRP-0519 suppresses all RNA synthesis activity.
Image credit: ppat.1009371
A Pearls article by Ludington and Ja
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