Skip to main content
Advertisement
Broad protective vaccination against systemic Escherichia coli with autotransporter antigens

February 17, 2023

Broad protective vaccination against systemic Escherichia coli with autotransporter antigens

This study identified a surface-exposed, pathogen-specific autotransporter protein, SinH, as a potential vaccine candidate for E. coli infection.

Image credit: Hawaii Dept. of Health

Read the latest Reviews in PLOS Pathogens

Peer-reviewed articles on topical areas of broad interest to the pathogens community.

Find Reviews

Recently Published Articles

Current Issue

Current Issue February 2023

02/22/2023

Research Article

Human ACE2 expression, a major tropism determinant for SARS-CoV-2, is regulated by upstream and intragenic elements

This study describes the creation of two mouse lines in which the ACE2, the protein Covid-19 binds to, chromosomal segment is replaced with the equivalent human DNA, showing qualitative and quantitative differences between ACE2 expression driven by the mouse and human promoters that are likely to impact disease progression in the two species.

Image credit: EMW

Human ACE2 expression, a major tropism determinant for SARS-CoV-2, is regulated by upstream and intragenic elements

02/23/2023

Review

Biogenesis of extracellular vesicles in protozoan parasites: The ESCRT complex in the trafficking fast lane?

This review sought to better understand the biogenesis of extracellular vesicles in protozoan parasites as a means to inform therapeutic interventions, with a focus on the Endosomal Sorting Complex Required for Transport machinery. This review highlights the diversity in EV biogenesis in protozoa, as well as the related involvement of the ESCRT system in these unique organisms.

Biogenesis of extracellular vesicles in protozoan parasites: The ESCRT complex in the trafficking fast lane?

Image credit: Camacho et al

02/23/2023

Pearls

The Cryptococcus wall: A different wall for a unique lifestyle

This review from Dr. Liliane Mukaremera aims to assess new insights into the unique attributes about the Cryptococcus cell wall in relation to the pathogenic lifestyle of these important pathogens

The Cryptococcus wall: A different wall for a unique lifestyle

Image credit: Wikipedia/Nephron

Get new content from PLOS Pathogens in your inbox

Thank you! You have successfully subscribed to the PLOS Pathogens newsletter.

Sorry, an error occurred while sending your subscription. Please try again later.

Try again
PLOS Pathogens | ISSN: 1553-7374 (online)