Cover
Special Issue
As human populations enjoy extended life expectancy and undergo the epidemiological transition to non-communicable diseases, growth in cancer incidence and prevalence is bringing about an urgent need for improvements in cancer diagnosis, treatment and care in many countries, calling for increased research and investment. In an Editorial, Beryne Odeny discusses the aims and contents of the journal's Special Issue on early cancer detection and minimal residual disease. Articles in the issue were selected along with Guest Editors Chris Abbosh, Sara-Jane Dawson and Charles Swanton, and document innovations that have the potential to inform cancer research, care and policy.
Image Credit: Cecil Fox, NCI, NIH
Editorial
Cancer Special Issue: Early detection and minimal residual disease
PLOS Medicine: published October 12, 2021 | https://doi.org/10.1371/journal.pmed.1003794
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Perspectives
COVID-19 and global equity for health: The good, the bad, and the wicked
PLOS Medicine: published October 1, 2021 | https://doi.org/10.1371/journal.pmed.1003797
ctDNA: An emerging neoadjuvant biomarker in resectable solid tumors
PLOS Medicine: published October 12, 2021 | https://doi.org/10.1371/journal.pmed.1003771
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Cesarean section: More than a maternal health issue
PLOS Medicine: published October 12, 2021 | https://doi.org/10.1371/journal.pmed.1003792
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Policy Forum
Medical journal requirements for clinical trial data sharing: Ripe for improvement
PLOS Medicine: published October 25, 2021 | https://doi.org/10.1371/journal.pmed.1003844
Guidelines and Guidance
Recommended reporting items for epidemic forecasting and prediction research: The EPIFORGE 2020 guidelines
PLOS Medicine: published October 19, 2021 | https://doi.org/10.1371/journal.pmed.1003793
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Collection Review
The global burden of Plasmodium vivax malaria is obscure and insidious
PLOS Medicine: published October 7, 2021 | https://doi.org/10.1371/journal.pmed.1003799
Research Articles
Different dose regimens of a SARS-CoV-2 recombinant spike protein vaccine (NVX-CoV2373) in younger and older adults: A phase 2 randomized placebo-controlled trial
PLOS Medicine: published October 1, 2021 | https://doi.org/10.1371/journal.pmed.1003769
The effects of an evidence- and theory-informed feedback intervention on opioid prescribing for non-cancer pain in primary care: A controlled interrupted time series analysis
PLOS Medicine: published October 4, 2021 | https://doi.org/10.1371/journal.pmed.1003796
Testing approaches to sharing trial results with participants: The Show RESPECT cluster randomised, factorial, mixed methods trial
PLOS Medicine: published October 4, 2021 | https://doi.org/10.1371/journal.pmed.1003798
The EmpaTeach intervention for reducing physical violence from teachers to students in Nyarugusu Refugee Camp: A cluster-randomised controlled trial
PLOS Medicine: published October 4, 2021 | https://doi.org/10.1371/journal.pmed.1003808
COVID-19 vaccination in Sindh Province, Pakistan: A modelling study of health impact and cost-effectiveness
PLOS Medicine: published October 4, 2021 | https://doi.org/10.1371/journal.pmed.1003815
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Fatal opioid overdoses during and shortly after hospital admissions in England: A case-crossover study
PLOS Medicine: published October 5, 2021 | https://doi.org/10.1371/journal.pmed.1003759
Impact of color-coded and warning nutrition labelling schemes: A systematic review and network meta-analysis
PLOS Medicine: published October 5, 2021 | https://doi.org/10.1371/journal.pmed.1003765
Clinical interventions for adults with comorbid alcohol use and depressive disorders: A systematic review and network meta-analysis
PLOS Medicine: published October 8, 2021 | https://doi.org/10.1371/journal.pmed.1003822
Behavioural activation to prevent depression and loneliness among socially isolated older people with long-term conditions: The BASIL COVID-19 pilot randomised controlled trial
PLOS Medicine: published October 12, 2021 | https://doi.org/10.1371/journal.pmed.1003779
Association of accelerometer-derived sleep measures with lifetime psychiatric diagnoses: A cross-sectional study of 89,205 participants from the UK Biobank
PLOS Medicine: published October 12, 2021 | https://doi.org/10.1371/journal.pmed.1003782
Characterising the nationwide burden and predictors of unkept outpatient appointments in the National Health Service in England: A cohort study using a machine learning approach
PLOS Medicine: published October 12, 2021 | https://doi.org/10.1371/journal.pmed.1003783
Associations between cesarean delivery and child mortality: A national record linkage longitudinal study of 17.8 million births in Brazil
PLOS Medicine: published October 12, 2021 | https://doi.org/10.1371/journal.pmed.1003791
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Transmission of community- and hospital-acquired SARS-CoV-2 in hospital settings in the UK: A cohort study
PLOS Medicine: published October 12, 2021 | https://doi.org/10.1371/journal.pmed.1003816
HMG-CoA reductase inhibitors and COVID-19 mortality in Stockholm, Sweden: A registry-based cohort study
PLOS Medicine: published October 14, 2021 | https://doi.org/10.1371/journal.pmed.1003820
Evaluation of progress toward universal health coverage in Myanmar: A national and subnational analysis
PLOS Medicine: published October 15, 2021 | https://doi.org/10.1371/journal.pmed.1003811
Modeling the epidemiological impact of the UNAIDS 2025 targets to end AIDS as a public health threat by 2030
PLOS Medicine: published October 18, 2021 | https://doi.org/10.1371/journal.pmed.1003831
Food biodiversity and total and cause-specific mortality in 9 European countries: An analysis of a prospective cohort study
PLOS Medicine: published October 18, 2021 | https://doi.org/10.1371/journal.pmed.1003834
Health and economic benefits of achieving hepatitis C virus elimination in Pakistan: A modelling study and economic analysis
PLOS Medicine: published October 19, 2021 | https://doi.org/10.1371/journal.pmed.1003818
Changes in the associations of race and rurality with SARS-CoV-2 infection, mortality, and case fatality in the United States from February 2020 to March 2021: A population-based cohort study
PLOS Medicine: published October 21, 2021 | https://doi.org/10.1371/journal.pmed.1003807
Offering ART refill through community health workers versus clinic-based follow-up after home-based same-day ART initiation in rural Lesotho: The VIBRA cluster-randomized clinical trial
PLOS Medicine: published October 21, 2021 | https://doi.org/10.1371/journal.pmed.1003839
Cancer risk in individuals with intellectual disability in Sweden: A population-based cohort study
PLOS Medicine: published October 21, 2021 | https://doi.org/10.1371/journal.pmed.1003840
Effectiveness of knowledge brokering and recommendation dissemination for influencing healthcare resource allocation decisions: A cluster randomised controlled implementation trial
PLOS Medicine: published October 22, 2021 | https://doi.org/10.1371/journal.pmed.1003833
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Evaluating the impact of DREAMS on HIV incidence among adolescent girls and young women: A population-based cohort study in Kenya and South Africa
PLOS Medicine: published October 25, 2021 | https://doi.org/10.1371/journal.pmed.1003837
Unmet need for hypercholesterolemia care in 35 low- and middle-income countries: A cross-sectional study of nationally representative surveys
PLOS Medicine: published October 25, 2021 | https://doi.org/10.1371/journal.pmed.1003841
Association of race and health insurance in treatment disparities of colon cancer: A retrospective analysis utilizing a national population database in the United States
PLOS Medicine: published October 25, 2021 | https://doi.org/10.1371/journal.pmed.1003842
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The estimated health impact of sodium reduction through food reformulation in Australia: A modeling study
PLOS Medicine: published October 26, 2021 | https://doi.org/10.1371/journal.pmed.1003806
Early childhood undernutrition, preadolescent physical growth, and cognitive achievement in India: A population-based cohort study
PLOS Medicine: published October 27, 2021 | https://doi.org/10.1371/journal.pmed.1003838
Corrections
Correction: Accuracy of novel antigen rapid diagnostics for SARS-CoV-2: A living systematic review and meta-analysis
PLOS Medicine: published October 13, 2021 | https://doi.org/10.1371/journal.pmed.1003825
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Correction: Immunogenicity of an oral rotavirus vaccine administered with prenatal nutritional support in Niger: A cluster randomized clinical trial
PLOS Medicine: published October 15, 2021 | https://doi.org/10.1371/journal.pmed.1003776