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February 2012

In the February issue of PLoS Medicine, Olav Lindqvist and colleagues describe the range of nonpharmacological caregiving activities provided by palliative care staff for cancer patients in the last days of life. Their findings demonstrate that nonpharmacological care at the end of life is multifaceted, with physical, psychological, social, spiritual, and existential care interwoven in caregiving activities. In a linked editorial, the PLoS Medicine Editors reflect on Lindqvist and colleagues' findings, and on their approach to the emotive and often taboo subject of caregiving for the dying. The Editors comment: “[The results of this study] reveal the complex and sometimes subtle caregiving approaches that palliative care staff take to improve the experience of dying for both patient and family…Research such as this not only provides hope that it is possible to have a good quality of death but also suggests that through research the experience of dying can be improved.”

Image Credit: Sam Caplat (samcaplat at


Mobile Phone Text Messaging: Tool for Malaria Control in Africa

Dejan Zurovac, Ambrose O. Talisuna, Robert W. Snow

The Evolving Landscape of the Economics of HIV Treatment and Prevention

Bohdan Nosyk, Julio S. G. Montaner

Engaging Men in Prevention and Care for HIV/AIDS in Africa

Edward J. Mills, Chris Beyrer, Josephine Birungi, Mark R. Dybul

Research Articles

Prevalence, Distribution, and Impact of Mild Cognitive Impairment in Latin America, China, and India: A 10/66 Population-Based Study

Ana Luisa Sosa, Emiliano Albanese, Blossom C. M. Stephan, Michael Dewey, Daisy Acosta, Cleusa P. Ferri, Mariella Guerra, Yueqin Huang, K. S. Jacob, Ivonne Z. Jiménez-Velázquez, Juan J. Llibre Rodriguez, Aquiles Salas, Joseph Williams, Isaac Acosta, Maribella González-Viruet, Milagros A. Guerra Hernandez, Li Shuran, Martin J. Prince, Robert Stewart

Association between Clean Delivery Kit Use, Clean Delivery Practices, and Neonatal Survival: Pooled Analysis of Data from Three Sites in South Asia

Nadine Seward, David Osrin, Leah Li, Anthony Costello, Anni-Maria Pulkki-Brännström, Tanja A. J. Houweling, Joanna Morrison, Nirmala Nair, Prasanta Tripathy, Kishwar Azad, Dharma Manandhar, Audrey Prost

Socioeconomic Factors and All Cause and Cause-Specific Mortality among Older People in Latin America, India, and China: A Population-Based Cohort Study

Cleusa P. Ferri, Daisy Acosta, Mariella Guerra, Yueqin Huang, Juan J. Llibre-Rodriguez, Aquiles Salas, Ana Luisa Sosa, Joseph D. Williams, Ciro Gaona, Zhaorui Liu, Lisseth Noriega-Fernandez, A. T. Jotheeswaran, Martin J. Prince

Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias

Robert Clarke, Derrick A. Bennett, Sarah Parish, Petra Verhoef, Mariska Dötsch-Klerk, Mark Lathrop, Peng Xu, Børge G. Nordestgaard, Hilma Holm, Jemma C. Hopewell, Danish Saleheen, Toshihiro Tanaka, Sonia S. Anand, John C. Chambers, Marcus E. Kleber, Willem H. Ouwehand, Yoshiji Yamada, Clara Elbers, Bas Peters, Alexandre F. R. Stewart, Muredach M. Reilly, Barbara Thorand, Salim Yusuf, James C. Engert, Themistocles L. Assimes, Jaspal Kooner, John Danesh, Hugh Watkins, Nilesh J. Samani, Rory Collins, Richard Peto, for the MTHFR Studies Collaborative Group

Complexity in Non-Pharmacological Caregiving Activities at the End of Life: An International Qualitative Study

Olav Lindqvist, Carol Tishelman, Carina Lundh Hagelin, Jean B. Clark, Maria L. Daud, Andrew Dickman, Franzisca Domeisen Benedetti, Maren Galushko, Urska Lunder, Gunilla Lundquist, Guido Miccinesi, Sylvia B. Sauter, Carl Johan Fürst, Birgit H. Rasmussen, on behalf of OPCARE9

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