December 2, 2019
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12/02/2019
Research Article
In a cohort study of men born in Sweden, Liesbeth Vandenput and colleagues investigate whether the timing of puberty can predict the risk of fracture later in life. Read the Author Summary.
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Browse Issues 2004 – 2019
11/27/2019
Research Article
Tara Templin and colleagues project the burden of obesity in 103 countries. Read the Author Summary.
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11/26/2019
Editorial
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11/26/2019
Research Article
John MacLeod and colleagues report on possible harms in people prescribed sedatives alongside opioid agonist therapy. Part of the Substance Use, Misuse and Dependence Special Issue. Read the Author Summary.
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11/26/2019
Research Article
Bai Li and colleagues reveal a healthy eating and activity intervention in Chinese children that reduces obesity. Read the Author Summary.
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11/26/2019
Research Article
Astrid Guttmann and colleagues reveal a high rate of mortality for mothers of neonatal abstinence syndrome children up to 10 years following birth. Part of the Substance Use, Misuse and Dependence Special Issue. Read the Author Summary.
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11/26/2019
Research Article
Natasha Martin and co-workers estimate the impact of increased use of opioid agonist therapy on initiation of injection drug use. Read the Author Summary, or the Special Issue on Substance Use, Misuse and Dependence.
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11/26/2019
Policy Forum
Alexander Tsai and co-authors discuss the role of stigma in responses to the US opioid crisis. Part of the Special Issue on Substance Use, Misuse and Dependence.
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11/26/2019
Research Article
Sarah McKetta and colleagues investigate associations between alcohol drinking and parenting among adults in the United States. Read the Author Summary, or the Substance Use Misuse and Dependence Special Issue.
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11/26/2019
Research Article
Thomas Kerr and co-authors investigate all-cause mortality in people who frequently used a supervised injection facility to inject drugs. Part of the Substance Use Special Issue.
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A new PLOS Collection, supported by the WHO, to identify and outline the optimal characteristics of clinical trial designs to inform policy guidance for new TB regimens.
In this Collection Review, Kelley Dooley and colleagues discuss incorporating modern preclinical drug development tools to improve and accelerate the designing and testing of new tuberculosis regimens.
Geraint Davies and colleagues discuss the potential for innovative early-phase clinical trial methods to improve the safety and efficiency of the tuberculosis drug development process.
Our most recent Special Issue, this collection focuses on new approaches to fighting and ending TB, including discovery and validation of novel biomarkers and diagnostic technologies, development of new treatments and testing of vaccines.
In this Collection Review for the Novel Treatments for Tuberculosis Collection, Piero Olliaro and Michael Vaillant discuss the considerations when choosing a non-inferiority margin that is meaningful from statistical, ethical, clinical, and health standpoint.
The PLOS Medicine team and several editorial board members have reflected upon the last decade and a half to identify the research they feel made the most impact on their communities.
PLOS Medicine's special issue devoted to the health impacts of climate change, Guest Edited by Jonathan Patz and Madeleine Thomson.
Modern statistical modeling techniques—often called machine learning—are posited as a transformative force for human health. This Special Issue explores the intersections of deep learning and health.
HIV infection continues to pose a critical risk to health in many countries. Read the research in our special issue and collection.
This collection, published in collaboration with WHO, focuses on global policy and systems aiming to achieve control of STIs and mitigation of their adverse effects on health.
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