January 21, 2020
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01/21/2020
Perspective
Giorgia Sulis and Madhukar Pai discuss the global distribution, and approaches to diagnosis and treatment, of isoniazid-resistant tuberculosis. Read the related Research Article.
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Browse Issues 2004 – 2019
01/17/2020
Research Article
Jinlei Qi and colleagues reveal the potential gains in life expectancy in China by reducing ambient PM2.5 concentrations. Read the Author Summary.
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01/15/2020
Research Article
In a systematic review, Christopher Cai and colleagues investigate the projected cost impact associated with a single-payer approach to health insurance in the United States. Read the Author Summary.
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01/09/2020
Research Article
In a nationwide longitudinal study, Sofie Holmquist and colleagues investigate the association between diagnosis of depression and subsequent diagnosis of dementia in population-based and sibling cohorts of Swedish individuals older than 50 years. Read the Author Summary.
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01/09/2020
Policy Forum
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01/06/2020
Research Article
Tuck Seng Cheng and colleagues examine the literature on the association between puberty timing and Type 2 diabetes. Read the Author Summary.
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01/02/2020
Research Article
Amanda Thrift and colleagues reveal the benefits of education around hypertension and improved lifestyle guidance for patients in rural India with high blood pressure. Read the Author Summary.
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12/31/2019
Research Article
Yaohua Tian and colleagues investigate the associations between ambient particulate matter concentrations and hospital admissions for pneumonia. Read the Author Summary.
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12/31/2019
Editorial
In December's editorial, Elvin Geng and co-authors discuss the role of adaptation in implementing effective therapies for prevention and treatment of HIV/AIDS.
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12/31/2019
Research Article
Monica Malta and co-authors report a systematic review on outcomes of opioid agonist therapy for incarcerated persons with opioid use disorder. Read the Author Summary or the Special Issue.
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A new PLOS Collection, supported by the WHO, to identify and outline the optimal characteristics of clinical trial designs to inform policy guidance for new TB regimens.
In this Collection Review, Kelley Dooley and colleagues discuss incorporating modern preclinical drug development tools to improve and accelerate the designing and testing of new tuberculosis regimens.
Geraint Davies and colleagues discuss the potential for innovative early-phase clinical trial methods to improve the safety and efficiency of the tuberculosis drug development process.
Our most recent Special Issue, this collection focuses on new approaches to fighting and ending TB, including discovery and validation of novel biomarkers and diagnostic technologies, development of new treatments and testing of vaccines.
In this Collection Review for the Novel Treatments for Tuberculosis Collection, Piero Olliaro and Michael Vaillant discuss the considerations when choosing a non-inferiority margin that is meaningful from statistical, ethical, clinical, and health standpoint.
The PLOS Medicine team and several editorial board members have reflected upon the last decade and a half to identify the research they feel made the most impact on their communities.
PLOS Medicine's special issue devoted to the health impacts of climate change, Guest Edited by Jonathan Patz and Madeleine Thomson.
Modern statistical modeling techniques—often called machine learning—are posited as a transformative force for human health. This Special Issue explores the intersections of deep learning and health.
HIV infection continues to pose a critical risk to health in many countries. Read the research in our special issue and collection.
This collection, published in collaboration with WHO, focuses on global policy and systems aiming to achieve control of STIs and mitigation of their adverse effects on health.
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