December 1, 2022

Discontinuation and tapering of prescribed opioids and risk of overdose among people on long-term opioid therapy for pain with and without opioid use disorder in British Columbia, Canada: A retrospective cohort study

In a retrospective cohort study from Canada, Dr Mary Kennedy and colleagues explore the effect of discontinuation and tapering of prescribed opioids on risk of overdose among people on long-term opioid therapy for pain with and without opioid use disorder.

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PLOS Medicine is experiencing high submission volumes.

Processing of new submissions will restart in January 2023 as new staff are onboarded. We apologise for the delay.

12/01/2022

Research Article

Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case–control analysis

Using a Test-Negative Case-Control Analysis, Dr Margaret L. Lind and colleagues, investigate the association between primary or booster COVID-19 mRNA vaccination and omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection.

Image credit: Hakan Nural, Unsplash

Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case–control analysis

Recently Published Articles

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Browse Issues 2004 – 2022

11/16/2022

Research Article

Scaling-up a pharmacist-led information technology intervention (PINCER) to reduce hazardous prescribing in general practices: Multiple interrupted time series study

In a multiple interrupted time series study, Dr. Amelia C. Taylor and colleagues explore scaling-up a pharmacist-led information technology intervention (PINCER) to reduce hazardous prescribing in general practices.

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Scaling-up a pharmacist-led information technology intervention (PINCER) to reduce hazardous prescribing in general practices: Multiple interrupted time series study

11/22/2022

Research Article

Interpregnancy interval and adverse pregnancy outcomes among pregnancies following miscarriages or induced abortions in Norway (2008-2016): A cohort study

In a Norwegian cohort study, Dr Gizachew Tessema and colleagues investigate the association between interpregnancy interval and adverse pregnancy outcomes, among pregnancies following miscarriages or induced abortions.

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Interpregnancy interval and adverse pregnancy outcomes among pregnancies following miscarriages or induced abortions in Norway (2008-2016): A cohort study

11/22/2022

Research Article

Planned mode of birth after previous cesarean section and risk of undergoing pelvic floor surgery: A Scottish population-based record linkage cohort study

In a Scottish population-based record linkage cohort study, Dr Kathryn E. Fitzpatrick and colleagues, investigate planned mode of birth and the risk of subsequent pelvic floor surgery following previous cesarean section.

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11/22/2022

Research Article

Vaccine effectiveness against SARS-CoV-2 reinfection during periods of Alpha, Delta, or Omicron dominance: A Danish nationwide study

Katrine Finderup Nielsen and colleagues investigate vaccine effectiveness against SARS-CoV-2 reinfection, COVID-19 related hospitalization and COVID-19 related death, in previously infected individuals in Denmark.

Image credit: Daniel Schludi, Unsplash

11/07/2022

Research Article

Risk and symptoms of COVID-19 in health professionals according to baseline immune status and booster vaccination during the Delta and Omicron waves in Switzerland—A multicentre cohort study

In this multi-centre cohort study from Switzerland, Dr Christian R. Kahlert and colleagues investigate the risk and symptoms of COVID-19 among healthcare professionals, according to baseline immune status and booster vaccination, during the Delta and Omicron waves.

Image credit: Ashkan Forouzani, Unsplash

10/31/2022

Perspective

The rapidly evolving Monkeypox epidemic: A call for action to leave no one behind

Dr. Steffanie Strathdee and colleagues reflect upon the “known knowns”, “known unknowns” and “unknown unknowns” of the evolving Monkeypox epidemic.

Image credit: Jernej Furman, Flickr

11/14/2022

Research Article

The association between multimorbidity and mobility disability-free life expectancy in adults aged 85 years and over: A modelling study in the Newcastle 85+ cohort

In a modelling study from Newcastle, Dr Laurie Davies and colleagues explore the association between multimorbidity and mobility disability-free life expectancy in adults aged 85 years and over.

Image credit: Steven HWG, Unsplash

11/10/2022

Research Article

Post-COVID-19-associated morbidity in children, adolescents, and adults: A matched cohort study including more than 157,000 individuals with COVID-19 in Germany

In a matched cohort study from Germany, including more than 157,000 individuals with COVID-19, Dr. Martin Roessler and colleagues investigate post COVID-19 associated morbidity in children, adolescents, and adults.

Image credit: Kelly Sikkema, Unsplash

11/10/2022

Research Article

Global SARS-CoV-2 seroprevalence from January 2020 to April 2022: A systematic review and meta-analysis of standardized population-based studies

In a systematic review and meta analysis, Isabel Bergeri, Mairead Whelan, Harriet Ware, Lorenzo Subissi, and colleagues study global SARS-CoV-2 seroprevalence, two years into the COVID-19 pandemic.

Image credit: Prasesh Shiwakoti (Lomash), Unsplash

Refugee and Migrant Health

Complex health associations among diverse contexts call for tailored and rights-based solutions

In an Editorial, Guest Editors Paul Spiegel, Terry McGovern and Kol Wickramage discuss the Special Issue.
Suffering and need for care in Rohingya refugees and caregivers in Bangladesh

Megan Doherty and co-workers report on illness, suffering and treatment needs among Rohingya refugees and caregivers in Bangladesh.
Healthcare factors associated with the risk of stillbirth in migrants in Western Australia

Maryam Mozooni and colleagues reveal the higher risk of intrapartum stillbirth for migrant women in Australia compared to Australian born women.
Exploring sources of insecurity for Ethiopian Oromo and Somali women who have given birth in Kakuma Refugee Camp

Amber Lalla and coll. explore sources of insecurity for Ethiopian and Somali women who have given birth in Kakuma Refugee Camp.

PLOS Medicine Collections

Regulatory Harmonization Collection

This Special Collection provides an overview of the East African Medicines Regulatory Harmonization Initiative, describes its progress thus far, and unveils the initiative’s roadmap for the next phase.
Substance Use, Misuse, and Dependence

This Special Issue highlights the diverse communities that work to support people and populations affected by substance use and misuse.
Maternal and Child Health & Nutrition

This 2019 Special Issue highlights the importance of nutrition for maternal and child health.

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PLOS Medicine | ISSN: 1549-1676 (online)

PLOS Medicine is experiencing high submission volumes.

Processing of new submissions will restart in January 2023 as new staff are onboarded. We apologise for the delay.

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