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First-trimester nonsteroidal anti-inflammatory drugs exposure and risk of major congenital malformations: A retrospective register-based cohort study

May 14, 2026

First-trimester nonsteroidal anti-inflammatory drugs exposure and risk of major congenital malformations: A retrospective register-based cohort study

In a retrospective register-based study, Ariel Hasidim, Itamar Shitrit and colleagues investigate the association between first trimester anti-inflammatory drug exposure and major congenital malformations, in a large Israeli cohort.

Image credit: Volodymyr Hryshchenko, Unsplash

05/11/2026

Perspective

Connected or chained by social media? Child and adolescent mental health in a digital era

In this Perspective, Silja Kosola outlines how social media disproportionately harms child and adolescent mental health, and argues that while recent policy changes aimed at protecting youth from social media are welcome, stricter age limits and greater accountability of social media companies are needed.

Connected or chained by social media? Child and adolescent mental health in a digital era

Image credit: Karsten Winegeart, Unsplash

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PLOS Medicine | ISSN: 1549-1676 (online)