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Table of Contents

January 2020

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Advances in cervical cancer prevention: Efficacy, effectiveness, elimination?
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Human papillomaviruses (HPV) cause several serious and life-threatening diseases, with cervical cancer having received the most attention. In recent years, effective vaccines protecting against the most high-risk HPV types have become available and are now provided to populations in many high-income countries. However, in low- and middle-income countries HPV vaccines are much less widely available at present, and in these settings population screening for cervical cancer and its precursors may also be absent.

In this month’s Editorial, Karin Sundström and Miriam Elfström discuss plans to roll-out HPV vaccines for prevention of cervical cancer and other diseases more generally, and consider the longer-term prospects for cervical cancer elimination.

Image Credit: Hey Paul Studios, Flickr

Editorial

Advances in cervical cancer prevention: Efficacy, effectiveness, elimination?

Karin Sundström, K. Miriam Elfström

PLOS Medicine: published January 28, 2020 | https://doi.org/10.1371/journal.pmed.1003035

Perspective

Isoniazid-resistant tuberculosis: A problem we can no longer ignore

Giorgia Sulis, Madhukar Pai

PLOS Medicine: published January 21, 2020 | https://doi.org/10.1371/journal.pmed.1003023

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Policy Forum

Infectious disease pandemic planning and response: Incorporating decision analysis

Freya M. Shearer, Robert Moss, Jodie McVernon, Joshua V. Ross, James M. McCaw

PLOS Medicine: published January 9, 2020 | https://doi.org/10.1371/journal.pmed.1003018

Research Articles

Effectiveness of a scalable group-based education and monitoring program, delivered by health workers, to improve control of hypertension in rural India: A cluster randomised controlled trial

Dilan Giguruwa Gamage, Michaela A. Riddell, Rohina Joshi, Kavumpurathu R. Thankappan, Clara K. Chow, Brian Oldenburg, Roger G. Evans, Ajay S. Mahal, Kartik Kalyanram, Kamakshi Kartik, Oduru Suresh, Nihal Thomas, Gomathyamma K. Mini, Pallab K. Maulik, Velandai K. Srikanth, Simin Arabshahi, Ravi P. Varma, Rama K. Guggilla, Fabrizio D’Esposito, Thirunavukkarasu Sathish, Mohammed Alim, Amanda G. Thrift

PLOS Medicine: published January 2, 2020 | https://doi.org/10.1371/journal.pmed.1002997

Association of puberty timing with type 2 diabetes: A systematic review and meta-analysis

Tuck Seng Cheng, Felix R. Day, Rajalakshmi Lakshman, Ken K. Ong

PLOS Medicine: published January 6, 2020 | https://doi.org/10.1371/journal.pmed.1003017

The association of depression with subsequent dementia diagnosis: A Swedish nationwide cohort study from 1964 to 2016

Sofie Holmquist, Anna Nordström, Peter Nordström

PLOS Medicine: published January 9, 2020 | https://doi.org/10.1371/journal.pmed.1003016

Projected costs of single-payer healthcare financing in the United States: A systematic review of economic analyses

Christopher Cai, Jackson Runte, Isabel Ostrer, Kacey Berry, Ninez Ponce, Michael Rodriguez, Stefano Bertozzi, Justin S. White, James G. Kahn

PLOS Medicine: published January 15, 2020 | https://doi.org/10.1371/journal.pmed.1003013

Potential gains in life expectancy by attaining daily ambient fine particulate matter pollution standards in mainland China: A modeling study based on nationwide data

Jinlei Qi, Zengliang Ruan, Zhengmin (Min) Qian, Peng Yin, Yin Yang, Bipin Kumar Acharya, Lijun Wang, Hualiang Lin

PLOS Medicine: published January 17, 2020 | https://doi.org/10.1371/journal.pmed.1003027

Prevalence and genetic profiles of isoniazid resistance in tuberculosis patients: A multicountry analysis of cross-sectional data

Anna S. Dean, Matteo Zignol, Andrea Maurizio Cabibbe, Dennis Falzon, Philippe Glaziou, Daniela Maria Cirillo, Claudio U. Köser, Lice Y. Gonzalez-Angulo, Olga Tosas-Auget, Nazir Ismail, Sabira Tahseen, Maria Cecilia G. Ama, Alena Skrahina, Natavan Alikhanova, S. M. Mostofa Kamal, Katherine Floyd

PLOS Medicine: published January 21, 2020 | https://doi.org/10.1371/journal.pmed.1003008

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  1. Isoniazid-resistant tuberculosis: A problem we can no longer ignore

Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study

Uma V. Mahajan, Vijay R. Varma, Michael E. Griswold, Chad T. Blackshear, Yang An, Anup M. Oommen, Sudhir Varma, Juan C. Troncoso, Olga Pletnikova, Richard O’Brien, Timothy J. Hohman, Cristina Legido-Quigley, Madhav Thambisetty

PLOS Medicine: published January 24, 2020 | https://doi.org/10.1371/journal.pmed.1003012

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  1. Correction: Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study

Comparison of aggregate and individual participant data approaches to meta-analysis of randomised trials: An observational study

Jayne F. Tierney, David J. Fisher, Sarah Burdett, Lesley A. Stewart, Mahesh K. B. Parmar

PLOS Medicine: published January 31, 2020 | https://doi.org/10.1371/journal.pmed.1003019

Evaluation of a clinical decision rule to guide antibiotic prescription in children with suspected lower respiratory tract infection in The Netherlands: A stepped-wedge cluster randomised trial

Josephine S. van de Maat, Daphne Peeters, Daan Nieboer, Anne-Marie van Wermeskerken, Frank J. Smit, Jeroen G. Noordzij, Gerdien Tramper-Stranders, Gertjan J. A. Driessen, Charlie C. Obihara, Jeanine Punt, Johan van der Lei, Suzanne Polinder, Henriette A. Moll, Rianne Oostenbrink

PLOS Medicine: published January 31, 2020 | https://doi.org/10.1371/journal.pmed.1003034