Table of Contents

March 2015

The theme for World TB Day 2015 is "Reach, Treat, Cure Everyone."

Currently, of the estimated 9 million people who develop TB worldwide each year, about one-third are not diagnosed, treated, or tracked by national TB programs.

In a Guest Editorial on World TB Day, Madhukar Pai and Puneet Dewan identify programmatic and policy changes needed to accelerate progress towards the goal of ending TB by 2035.

Image Credit: Madhukar Pai


Testing and Treating the Missing Millions with Tuberculosis

Madhukar Pai, Puneet Dewan

Health in Action

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

Cathie Sudlow, John Gallacher, Naomi Allen, Valerie Beral, Paul Burton, John Danesh, Paul Downey, Paul Elliott, Jane Green, Martin Landray, Bette Liu, Paul Matthews, Giok Ong, Jill Pell, Alan Silman, Alan Young, Tim Sprosen, Tim Peakman, Rory Collins

Policy Forums

Paying Physicians to Prescribe Generic Drugs and Follow-On Biologics in the United States

Ameet Sarpatwari, Niteesh K. Choudhry, Jerry Avorn, Aaron S. Kesselheim

Strengthening the Detection of and Early Response to Public Health Emergencies: Lessons from the West African Ebola Epidemic

Mark J. Siedner, Lawrence O. Gostin, Hilarie H. Cranmer, John D. Kraemer

Research Articles

Ultra-Sensitive Detection of Plasmodium falciparum by Amplification of Multi-Copy Subtelomeric Targets

Natalie Hofmann, Felista Mwingira, Seif Shekalaghe, Leanne J. Robinson, Ivo Mueller, Ingrid Felger

Association between Traffic-Related Air Pollution in Schools and Cognitive Development in Primary School Children: A Prospective Cohort Study

Jordi Sunyer, Mikel Esnaola, Mar Alvarez-Pedrerol, Joan Forns, Ioar Rivas, Mònica López-Vicente, Elisabet Suades-González, Maria Foraster, Raquel Garcia-Esteban, Xavier Basagaña, Mar Viana, Marta Cirach, Teresa Moreno, Andrés Alastuey, Núria Sebastian-Galles, Mark Nieuwenhuijsen, Xavier Querol

CD47 Agonist Peptides Induce Programmed Cell Death in Refractory Chronic Lymphocytic Leukemia B Cells via PLCγ1 Activation: Evidence from Mice and Humans

Ana-Carolina Martinez-Torres, Claire Quiney, Tarik Attout, Heloïse Boullet, Linda Herbi, Laura Vela, Sandrine Barbier, Danielle Chateau, Elise Chapiro, Florence Nguyen-Khac, Frédéric Davi, Magali Le Garff-Tavernier, Roba Moumné, Marika Sarfati, Philippe Karoyan, Hélène Merle-Béral, Pierre Launay, Santos A. Susin

Broad Blockade Antibody Responses in Human Volunteers after Immunization with a Multivalent Norovirus VLP Candidate Vaccine: Immunological Analyses from a Phase I Clinical Trial

Lisa C. Lindesmith, Martin T. Ferris, Clancy W. Mullan, Jennifer Ferreira, Kari Debbink, Jesica Swanstrom, Charles Richardson, Robert R. Goodwin, Frank Baehner, Paul M. Mendelman, Robert F. Bargatze, Ralph S. Baric

Development and Validation of a Risk Score for Chronic Kidney Disease in HIV Infection Using Prospective Cohort Data from the D:A:D Study

Amanda Mocroft, Jens D. Lundgren, Michael Ross, Matthew Law, Peter Reiss, Ole Kirk, Colette Smith, Deborah Wentworth, Jacqueline Neuhaus, Christoph A. Fux, Olivier Moranne, Phillipe Morlat, Margaret A. Johnson, Lene Ryom, D:A:D study group, the Royal Free Hospital Clinic Cohort, and the INSIGHT, SMART, and ESPRIT study groups

Formal Comments

HIV Treatment-As-Prevention Research: Taking the Right Road at the Crossroads

Richard Hayes, Sarah Fidler, Anne Cori, Christophe Fraser, Sian Floyd, Helen Ayles, Nulda Beyers, Wafaa El-Sadr, HPTN 071 (PopART) Study Team

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