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February 27, 2025

PLOS statement on recent US Executive Orders

PLOS remains committed to open science principles: integrity, transparency, inclusivity, and collaboration. Read more on our blog. 

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07/27/2025

research article

Determinants of photoplethysmography signal quality at the wrist

Wrist photoplethysmogram (PPG) signals are widely used for physiological monitoring in consumer devices. However, the PPG is highly susceptible to noise, which can reduce the accuracy of monitored parameters. The aim of this study was to identify factors which influence PPG signal quality. 

Image credit: Anubhav Arora

Determinants of photoplethysmography signal quality at the wrist

07/30/2025

research article

Developing artificial intelligence tools for institutional review board pre-review: A pilot study on ChatGPT’s accuracy and reproducibility

We assessed the baseline performance of generative AI in analyzing clinical research protocols and informed consent forms. The goal was to determine whether these models could accurately and consistently extract ethically relevant information, including the research objectives, background, and risks and benefits.

Developing artificial intelligence tools for institutional review board pre-review: A pilot study on ChatGPT’s accuracy and reproducibility

Image credit: Pawel Czerwinski

04/17/2025

research article

A BLE based turnkey indoor positioning system for mobility assessment in aging-in-place settings

Indoor positioning systems (IPS) can be used to measure mobility at home, which is an important indicator for health and wellbeing. In this work, we designed and developed a Bluetooth Low Energy (BLE) based IPS that identifies individual users; does not require floorplans; and allows the end-users to perform on-site install/setup.

A BLE based turnkey indoor positioning system for mobility assessment in aging-in-place settings

Image credit: Wang et al

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PLOS Digital Health | ISSN: 2767-3170 (online)