May 23, 2023
Image credit: Flickr user Ganesh Subramaniam
05/25/2023
Research Article
Oliver Eales, Steven Riley and colleagues investigate how the severity of effects of the SARS-CoV-2 virus in England was affected by the mass vaccination campaign and emergence of Alpha, Delta and Omicron variants between May 2020 and March 2022.
Image credit: pbio.3002118
Current Issue April 2023
05/25/2023
Research Article
Life-history optimization predicts delays in maturity with decreasing mortality, altering the size-fecundity relationship. Mariana Álvarez-Noriega, Dustin Marshall and co-authors show that for marine fishes, these predictions match observed latitudinal gradients, with a delayed maturity and steeper increases in fecundity with body mass at high latitudes, including sensitivity to climate change.
Image credit: Flickr user Jon Connell
05/23/2023
Short Reports
Aging is one of the strong risk factors for the most common diseases on our planet, but we have few interventions that delay aging (including dietary restriction). Robert Rogers, Vamsi Mootha and co-workers reveal that a different type of restriction - oxygen restriction - can extend lifespan and counter neurological demise in a mouse model of accelerated aging.
Image credit: Caspar David Friedrich
05/19/2023
Research Article
The superior colliculus, a conserved midbrain node with extensive long-range connectivity throughout the brain, is a key structure for innate behaviors. This study by Alexander Growth, Jesús Martín-Cortecero and co-workers uses trans-synaptic tracing and functional analysis to reveal novel pathways via the superior colliculus for the transformation of cortical signals into long-range output signals in the mouse whisker.
Image credit: pbio.3002126
05/19/2023
Methods and Resources
Bacterial metabolism is important for human health, but most mechanistic insight relies on a few model organisms. This study by Peter Turnbaugh and colleagues uses a systems biology approach to explore the unusual metabolism of the prevalent and disease-linked gut actinobacterium Eggerthella lenta.
Image credit: pbio.3002125
05/19/2023
Methods and Resources
This manuscript by Liza Konnikova, Shalev Itzkovitz and colleagues presents a single cell atlas of human neonatal and necrotizing enterocolitis-affected small intestinal tissue, revealing cellular dysregulation that occurs in this disease and identifying new targets for future biomarker and therapeutic studies.
Image credit: pbio.3002124
05/25/2023
Perspective
In a pandemic, the virus, disease, and societal disaster each represent a different entity; Alexander Gorbalenya, and Stanley Perlman call for a rethink of how we use names in a pandemic.
Image credit: David Goodsell
05/23/2023
Essay
Aleksandra Petrovic Fabijan, Stephen Abedon and co-authors discuss how, despite being developed 100 years ago, phage therapy is currently experiencing a resurgence in interest.
Image credit: Steven McQuinn & Stephen Abedon
05/15/2023
Essay
In this Essay by Stephanie Jurburg and co-workers, the authors argue that new experimental designs are required to characterize the full spectrum of viral interactions, including mutualism and commensalism.
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Image credit: Stephanie Jurburg and Erik Hom
05/09/2023
Perspective
The recently described decline effect in ocean acidification impacts on fish behavior should not be equated with negligible effects; Andrew Esbaugh uses existing mechanistic data to argue against “throwing the baby out with the bathwater.”
Image credit: pbio.3002113
This collection explores biological solutions that could be applied to reduce CO2 emissions, get rid of non-degradable plastics, produce food in a sustainable manner or generate energy.
This collection explores potential solutions to mitigate the impacts of human activity on ocean ecosystems to minimize or reverse degradation.
To mark 200 years since the birth of Gregor Mendel, this collection looks back at the impact of his original research and asks how well it stands up to modern views on genetics.
Nearly 50 years after researchers first found specks of plastic floating in the Atlantic Ocean, microplastics are everywhere. This collection contains evidence-based commentaries on the diverse impacts of microplastics.
How will global climate change affect the dynamics and distribution of pathogens and their plant and animal hosts? This collection features four papers that attempt to unravel some of the underlying complexity.
June 7 - 9
Meet Senior Editor Luke Smith (lsmith@plos.org) - Virtual
June 11 - 16
Meet Senior Editor Ines Alvarez-Garcia (ialvarez-garcia@plos.org)
June 12 - 13
Meet Senior editor Roli Roberts (rroberts@plos.org)
June 22 - 23
Meet Editor in Chief Nonia Pariente (npariente@plos.org)
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