October 18, 2024
Image credit: pbio.3002868
10/18/2024
Short Reports
Mycobacterium tuberculosis bacteria express several MmpL membrane protein transporters that are critical for the export of lipid components for cell wall biogenesis. Rakesh Maharjan, Zhemin Zhang, Philip Klenotic, Edward Yu and co-workers solve the first cryo-EM structures of the subclass I MmpL4 and MmpL5 proteins, providing insights into substrate translocation.
Image credit: pbio.3002874
Current Issue September 2024
10/17/2024
Research Article
CHARGE syndrome results from aberrant neural crest development, affecting eye, heart, and facial structures, and has been attributed to pathogenic variants of the chromatin remodeler CHD7. Ruth Williams, Tatjana Sauka-Spengler and co-authors characterize the enhancers and tissue specific transcription factors that regulate Chd7 expression in the developing chick and human neural crest.
Image credit: pbio.3002786
10/15/2024
Research Article
Although animals implement diverse strategies to avoid hostile confrontations, the extent to which social influences affect escape tactics is unclear. Rachel Clein, Megan Warren and Joshua Neunuebel use innovative computational tools to reveal that male mice avoid conflict by exploiting nearby females to divert the attention of a pursuing aggressor in a "bait-and-switch" strategy.
Image credit: pbio.3002496
10/14/2024
Research Article
Interneurons control the timing of activation of excitatory neurons, but how single interneurons affect synchrony in vivo is unclear. Marco Bocchio, Artem Vorobyev, Rosa Cossart and colleagues show that CA1 hippocampus interneurons form a functionally connected network that promotes synchrony between pyramidal cells at the single neuron level.
Image credit: Vasiliy Solodovnikov
10/14/2024
Research Article
Epithelial tissues undergo remodeling during development and maintenance, so cell elimination rate must be coordinated with cell proliferation. Kevin Yuswan, Xiaofei Sun, Erina Kuranaga and Daiki Umetsu show that accelerated cell removal is associated with switching from isolated to clustered apoptosis, induced by the reduction of endocytosis and EGFR signaling.
Image credit: pbio.3002823
10/14/2024
Research Article
Why do bacterial species vary so much in their transformation rates? A study of Legionella and Acinetobacter, by Fanny Mazzamurro, Xavier Charpentier, Eduardo Rocha and colleagues, shows that transformation rates evolve by rapid changes, likely caused by intragenomic conflicts between mobile genetic elements and the host bacterium.
Image credit: pbio.3002814
09/19/2024
Perspective
This Perspective article describes PRO-MaP, which aims to increase and improve the reporting of detailed, structured and open methods and reusable step-by-step protocols in the life sciences.
Image credit: European Union
09/16/2024
Consensus View
There is currently no suitable system to classify circulating dengue virus (DENV) variants. This Consensus View proposes a new nomenclature system and free online tools to identify and track lineages of potential epidemiological and/or clinical importance.
Image credit: pbio.3002834
09/10/2024
Essay
For those who want to share their code but don't know where to start, this Essay distils dozens of articles on reproducibility and research software, collecting the most important practical details of how to provide computational transparency even if you aren't a trained software developer.
Image credit: pbio.3002815
09/09/2024
Perspective
The open science movement has gained ground, but improvements to the practice of science move at a glacial pace. This Perspective explores the misaligned incentives that are hindering progress to more open, reproducible research.
Image credit: Pixabay user PIRO4D
Translating conservation and biodiversity research from the field into the real world is a complex problem. This collection discusses issues around economics, policy, and how to do research that answers questions that decision makers have.
Symbiosis research has become a holistic and pervasive field with a mature theoretical basis. This collection showcases symbiotic relationships across the tree of life, exploring their evolutionary basis and underlying mechanisms.
PLOS Biology is 20 and we are celebrating with a collection that contains articles that look back at landmark studies that we published, others that look past and future, and others discussing how publishing and open science have evolved and what is to come.
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This collection explores engineering strategies to help us adapt plants to a changing climate, including breeding techniques, genome engineering, synthetic biology and microbiome engineering.
The green collection explores biological solutions that could be applied to reduce CO2 emissions, get rid of non-degradable plastics, produce food in a sustainable manner or generate energy.
October 21 - 24
Meet Editor in Chief Nonia Pariente (npariente@plos.org)
October 23 - 25
Meet Senior Magazine Editor Daniel Routledge (droutledge@plos.org).
October 29 - November 2
Meet Associate Editor Melissa Vazquez Hernandez (mvazquezhernandez@plos.org).
December 14 - 18
Meet Ines Alvarez-Garcia (ialvarez-garcia@plos.org)
December 10 - 13
Meet Senior Editor Roli Roberts (rroberts@plos.org)
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