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Division of labor in magnetotactic bacterial consortia

July 11, 2024

Division of labor in magnetotactic bacterial consortia

Multicellular magnetotactic bacteria (MMB) are unique in having no unicellular stage in their life cycle. George Schaible, Roland Hatzenpichler and colleagues reveal that individual cells within MMB consortia are not genetically identical and exhibit significant metabolic differentiation, highlighting their degree of complexity. Don't miss the Primer by Kayla Stoy and Will Ratcliff.

Image credit: George Schaible & Roland Hatzenpichler

PLOS Biologue

Community blog for PLOS Biology, PLOS Genetics and PLOS Computational Biology.

PLOS BIOLOGUE

07/12/2024

Research Article

Dopamine and acetylcholine in decision-making

Tradeoffs between potential rewards and associated costs involve the dopaminergic system, which antagonistically interacts with the cholinergic system. Mani Erfanian Abdoust, Gerhard Jocham and co-authors show that dopamine and acetylcholine have opposing effects on the modulation of specific components of cost-benefit decision making in humans.

Image credit: Public domain

Dopamine and acetylcholine in decision-making

Recently Published Articles

Current Issue

Current Issue June 2024

07/12/2024

Research Article

Engram cells and fear generalization

Fear generalization is a maladaptive response to harmless stimuli or situations that is characteristic of posttraumatic stress disorder and other anxiety disorders. Kun Cui, You Wan, Ming Yi and co-workers show that competition between engram and non-engram cells in the dentate gyrus determines whether fear generalization occurs.

Image credit: pbio.3002679

Engram cells and fear generalization

07/11/2024

Research Article

Nucleotide availability and NGLY1 deficiency

Regulation of the proteasome is disrupted in the rare genetic disease known as NGLY1 deficiency. Katherine Yanagi, Gary Ruvkun, Nicolas Lehrbach and colleagues find that proteasome dysfunction in NGLY1-deficient C. elegans depends on nucleotide availability, suggesting that interventions to alter nucleotide availability might mitigate proteasome insufficiency in diseases associated with proteasome dysfunction.

Image credit: pbio.3002720

Nucleotide availability and NGLY1 deficiency

07/11/2024

Research Article

Astrocyte activation and cognitive decline

Jae-Hong Kim, Il-Sung Jang, Kyoungho Suk and co-workers show that repetitive and sustained stimulation of hippocampal astrocytes induces reactive astrogliosis and subsequent LCN2 release, triggering neuroinflammation, inhibition of NMDA-receptor-related neuronal activity and cognitive impairment. Check out the accompanying Primer by Kirsten Bohmbach and Christian Henneberger

Astrocyte activation and cognitive decline

Image credit: pbio.3002687

07/11/2024

Methods and Resources

A database of global tetrapod traits

Tetrapods are model systems for global biodiversity science, but continuing data gaps and limited data standardization potentially introduce biases. Mario Moura, Walter Jetz and colleagues present TetrapodTraits, a database of 33,281 tetrapod species, integrating taxonomic, spatial, phylogenetic and attribute data through phylogeny-based multiple imputation.

A database of global tetrapod traits

Image credit: Mario Moura & Alexander Pyron

07/10/2024

Short Reports

The birth of myelinating oligodendrocytes

Oligodendrocyte precursor cells are a diverse population, but how does this functional diversity arise? Shayan Moghimyfiroozabad, Fekrije Selimi and co-authors show that C1ql1 expression defines a subpopulation of oligodendrocyte precursor cells that are indispensable for production of oligodendrocytes and myelin during postnatal brain development. Also read the related Primer by Tim Czopka.

The birth of myelinating oligodendrocytes

Image credit: pbio.3002655

07/08/2024

Essay

The new science of sleep

Omer Sharon, Eti Ben Simon, Matthew Walker and co-authors highlight eight of the most exciting new discoveries within sleep science, discussing how these have expanded our understanding of sleep's function at the cellular, organismal, and societal levels.

The new science of sleep

Image credit: pbio.3002684

07/01/2024

Unsolved Mystery

The mysteries of mitochondrial shape

Mitochondria come in many shapes and sizes. Noga Preminger and Maya Schuldiner explore the diverse processes that influence mitochondrial shape and network formation, highlighting gaps in our understanding of mitochondrial architecture.

The mysteries of mitochondrial shape

Image credit: pbio.3002671

06/11/2024

Editorial

Aligning data with decisions

The planetary outlook for biodiversity is dire. Leah Gerber and Gwenllian Iacona introduce a new Collection of articles that discuss the data we have and the data we need for more effective conservation policies.

Aligning data with decisions

Image credit: Leah Gerber

06/10/2024

Essay

Costs in conservation

Vanessa Adams investigates why more progress has not been made in considering economic costs in conservation, and highlights common mistakes made when selecting, estimating, and including costs in conservation decisions.

Costs in conservation

Image credit: pbio.3002676

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