09/30/2022
Research article
Giulia Concina, Benedetto Sacchetti and co-authors reveal that the occurrence of a prior fear experience allows new memories to be stored in the cortex immediately, without the need of the prolonged reorganization of brain circuits that characterizes the system memory consolidation.
Image credit: pbio.3001789
Current Issue August 2022
09/29/2022
Primer
Neurons lack the ability to regenerate after injury. Mary Tapia and Kevin Park explore a new preregistered study in PLOS Biology that finds that pharmacologically boosting regenerative capacity long after injury in mice, together with an enriched animal environment, promotes axonal and synaptic plasticity.
Image credit: pbio.3001830
09/29/2022
Research Article
Falling asleep at the wrong time can be dangerous. Stephane Dissel, Markus Klose, Paul Shaw and colleagues show that both time-restricted feeding and acute starvation enhance subsequent waking by reducing sleep drive. Thus internal state modulates sleep-promoting neurons to help animals maintain wakefulness in life-threatening conditions.
Image credit: pbio.3001797
09/28/2022
Research Article
A study on evolution of antimicrobial resistance, by Jennifer Jagdmann, Dan Andersson and Hervé Nicoloff, reveals how sub-inhibitory concentrations of antibiotics enrich and select for a mutated allele that prevents evolution towards clinically significant levels of antibiotic resistance.
Image credit: pbio.3001808
09/28/2022
Primer
Leaf veins provide a vital transport route in plants, and the formation of vein patterns has fascinated many scientists over the years. Leah Band explores a new PLOS Biology study which reveals how transport through plasmodesmata plays a key role in vein patterning.
Image credit: pbio.30017811
09/28/2022
Research Article
During cytokinesis, it is known that unique lipids with specific biophysical properties are localized to intercellular bridges connecting the two dividing cells, but how does this occur? Govind Kunduri, Usha Acharya, Jairaj Acharya and co-workers show that multivesicular bodies deliver sphingolipids to the ingressing membranes during male meiotic cytokinesis.
Image credit: pbio.3001599
09/23/2022
Essay
How might vaccination campaigns affect the evolution of viruses? This Essay explores what is currently known about viral evolution in the context of vaccination, with an eye towards the future evolution of SARS-CoV-2.
Image credit: pbio.3001804
09/22/2022
Methods and Resources
Babesia is a genus of apicomplexan parasites that infect vertebrate red blood cells. Single-cell RNA sequencing of three Babesia species to map the replication cycle and construct pseudo-synchronized time-course gene expression profiles.
Image credit: pbio.3001816
09/22/2022
Discovery Report
Primary and metastatic tumors have discrete requirements for glycolysis- or respiration-derived ATP, suggesting that tumors in different anatomic sites develop metabolic heterogeneity. Also read the related Primer.
Image credit: pbio.3001753
09/21/2022
Primer
This Primer explores a new study which suggests that the emergence of clusters of parvalbumin neurons in the forebrain could reflect a convergent mechanism underlying the evolution of skilled behaviors in birds.
Image credit: pbio.3001795
To mark 200 years since the birth of Gregor Mendel, this collection looks back at the impact of his original research and asks how well it stands up to modern views on genetics.
Nearly 50 years after researchers first found specks of plastic floating in the Atlantic Ocean, microplastics are everywhere. This collection contains evidence-based commentaries on the diverse impacts of microplastics.
How will global climate change affect the dynamics and distribution of pathogens and their plant and animal hosts? This collection features four papers that attempt to unravel some of the underlying complexity.
October 5 - 8
Meet Senior Editor Roli Roberts
October 5 - 9
Meet Associate Editor Luke Smith
October 6 - 7
Meet Editor in Chief Nonia Pariente
October 9 - 10
Meet Senior Editor Ines Alvarez-Garcia
October 23 - 26
Meet Senior Editor Kris Dickson
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