01/19/2023
Research Article
What happens to the mammary gland after breast-feeding?
How are tissue remodeling, organ disassembly and the reversal of this process coordinated? Using the post-lactating mammary gland where a precisely orchestrated process shrinks the organ back to quiescence, Aleksandr Mironov, Matthew Fisher, Nasreen Akhtar and colleagues reveal that the small GTPase Rac1 plays a central role in restraining cell turnover, allowing reversibility from death if feeding recommences.
Image credit: Nasreen Akhtar and Matthew Fisher
Connect with Us