August 13, 2019
Image credit: Flickr user Zappys Technology Solutions
08/09/2019
Methods and Resources
Guillaume Blin, Sally Lowell and co-authors present Nessys, a new computational method allows researchers to measure the properties of individual nuclei in situations in which cells are tightly packed together, for example, during differentiation of stem cells in culture or during early postimplantation development.
Image credit: pbio.3000388
Current Issue July 2019
08/15/2019
Research Article
Computational modeling and experiments with Arabidopsis thaliana, by Mark Greenwood, James Locke and colleagues, reveal a new mechanism for the coordination of circadian timing across an organism, acting through a combination of organ-specific sensitivity to environmental inputs and local cell-cell coupling.
Image credit: James Locke
08/13/2019
Research Article
Low temperatures delay aging and promote longevity in many organisms. Dongyeop Lee, Seon Woo An, Yoonji Jung, Seung-Jae Lee and co-workers show that at low ambient temperatures, Mediator 15, a transcriptional coregulator, allows the nematode Caenorhabditis elegans to live longer by increasing the levels of unsaturated lipids, helping to maintain protein homeostasis.
Image credit: pbio.3000415
08/12/2019
Research Article
The brain activity detected during pain could be due merely to the fact that pain is arousing and attention-grabbing, rather than being directly attributable to the pain itself. Björn Horing, Christian Sprenger and Christian Büchel identify an area of the brain — the parietal operculum — whose activity can only be explained by the painfulness of pain.
Image credit: pbio.3000205
08/09/2019
Research Article
Laxmi Shanker Rai, Kaustuv Sanyal and colleagues find that a variant histone H3 specific to the CTG clade of ascomycete fungi modulates the expression of the majority of the biofilm genes in the human pathogen Candida albicans by binding differentially to biofilm-relevant gene promoters.
Image credit: pbio.3000422
08/09/2019
Research Article
Task-irrelevant distractors can automatically capture attention when they were previously associated with a high reward. Sirawaj Itthipuripat, Vy Vo, Thomas Sprague and John Serences show that these high-valued distractors increased the fidelity of neural representations in retinotopically organized regions of visual cortex.
Image credit: pbio.3000186
08/15/2019
Primer
Case studies of the evolution of molecular machines remain scarce. Morgan Beeby explores a recent study describing the evolution of a functionally diverse family of such machines: the Bacterial and Archaeal Type IV filament family.
Image credit: pbio.3000390
08/12/2019
Community Page
John Ioannidis, Jeroen Baas, Richard Klavans, Kevin Boyack present a publicly available database that provides standardized information on multiple citation indicators, annotating each author according to his/her main scientific field(s).
Image credit: Flickr user Gael Varoquaux
08/06/2019
Research Article
Pelagic baited cameras reveal the last refuges of declining shark populations, showing that proximity to human activity centres is increasingly limiting the distribution of sharks, and that there is a mismatch between protected areas and the remaining shark hotspots.
Image credit: pbio.3000366
08/06/2019
Research Article
The neural basis of a sophisticated attentional system that is able to differentially distribute feature-based attention such that the strongest attentional modulation is directed towards those neurons that are the most informative contributors to the task at hand.
Image credit: pbio.3000387
Raquel Lieberman discusses her work on the protein myocilin, implicated in glaucoma, but whose normal function remains unclear after over 20 years.
Susanna Bidgood explores the future of using poxviruses as versatile tools for cell biology research.
Rachel Harding proposes that open notebooks present an opportunity for researchers to showcase their work and rapidly advance science in their field
On the eve of the UN General Assembly meeting on TB, Christoph Grundner urged the need to consider basic research as an essential component of any future anti-TB strategy.
Norman Pace remembers the early days of what became known as "metagenomics," as experienced by the author during his development as a scientist.
Meet Senior Editor Roli Roberts in Manchester, UK
July 21-25, 2019
Meet Senior Editor Ines Alvarez-Garcia in Krakow, Poland.
June 11-16, 2019
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