08/29/2024
Research Article
Empirical data on occurrences and vulnerability are still lacking for most marine teleost fish species. Nicolas Loiseau, Nicolas Mouquet and colleagues use machine learning with occurrence data, species biological traits, taxonomy and human usage to infer a 12.8% extinction risk for marine fish species, surpassing existing estimates.
Image credit: pbio.3002773
Current Issue August 2024
08/29/2024
Research Article
The chelicerate body plan is unique among arthropods because segments are divided into two tagmata – cephalothorax and abdomen – but the mechanisms that establish the boundary between them remain unclear. Emily Setton, Prashant Sharma and co-workers identify a new gene named waist-less that is required for patterning the spider body plan.
Image credit: pbio.3002771
08/27/2024
Short Reports
Bemnifosbuvir (AT-527) and AT-752 are broad-spectrum antiviral guanosine analogues currently in clinical trials. Aurélie Chazot, François Ferron, Bruno Canard and colleagues reconstitute their intracellular 5-step enzymatic activation pathway, characterizing each enzymatic complex at atomic resolution, which provides insight into substrate binding and drug activation.
Image credit: pbio.3002743
08/26/2024
Research Article
How cells respond to defects in nuclear reassembly after mitosis? Jingjing Li, Vincent Archambault and co-authors show that damaged cells in Drosophila are either removed by apoptosis or activate a p53-dependent cell cycle checkpoint to maintain tissue integrity.
Image credit: pbio.3002780
08/26/2024
Research Article
Inhibitory circuits in the mammalian olfactory bulb shape information as it propagates from peripheral receptors to the downstream cortex. Shawn Burton, Christina Malyshko and Nathaniel Urban show that fast-spiking interneurons perisomatically inhibit projection neurons in the mammalian olfactory bulb via synaptic detonation.
Image credit: pbio.3002660
08/23/2024
Research Article
Germ cell apoptosis in C. elegans hermaphrodites eliminates around 60% of all cells in meiotic prophase to maintain tissue homeostasis. Tea Kohlbrenner, Alex Hajnal and colleagues show that the size of meiotic germ cells is reduced by apical actomyosin constriction, which triggers apoptosis in the C. elegans germline.
Image credit: pbio.3002775
08/29/2024
Unsolved Mystery
Manuel Ares-Arroyo, Charles Coluzzi, Jorge Moura de Sousa and Eduardo Rocha explore how microbial evolution is shaped by mobile genetic elements regulating each other. These functional dependencies raise numerous questions.
Image credit: pbio.3002796
08/29/2024
Essay
Following Niko Tinbergen’s roadmap for behavioral investigation, Reut Vardi, Valerio Sbragaglia and colleagues show how using videos, photos, text, and audio posted online can shed new light on known behaviors and lead to the discovery of new ones.
Image credit: pbio.3002793
08/26/2024
Community Page
James Canham, Joe Win, Sophien Kamoun and colleagues introduce GetGenome, a non-profit organization that aims to provide global and affordable access to genomics technology and training.
Image credit: pbio.3002804
08/26/2024
Perspective
Stathis Megas, Sarah Teichmann and co-authors link molecular and morphological cell features in three dimensions across scales, using machine learning and artificial intelligence to reveal emergent properties of complex biological systems.
Image credit: pbio.3002803
Translating conservation and biodiversity research from the field into the real world is a complex problem. This collection discusses issues around economics, policy, and how to do research that answers questions that decision makers have.
Symbiosis research has become a holistic and pervasive field with a mature theoretical basis. This collection showcases symbiotic relationships across the tree of life, exploring their evolutionary basis and underlying mechanisms.
PLOS Biology is 20 and we are celebrating with a collection that contains articles that look back at landmark studies that we published, others that look past and future, and others discussing how publishing and open science have evolved and what is to come.
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This collection explores engineering strategies to help us adapt plants to a changing climate, including breeding techniques, genome engineering, synthetic biology and microbiome engineering.
The green collection explores biological solutions that could be applied to reduce CO2 emissions, get rid of non-degradable plastics, produce food in a sustainable manner or generate energy.
September 1 - 4
Meet Associate Editor Melissa Vazquez Hernandez (mvazquezhernandez@plos.org)
September 9 - 11
Meet Senior Editor Ines Alvarez-Garcia (ialvarez-garcia@plos.org)
September 9 - 10
Meet Associate Editor Suzanne de Bruijn (sbruijn@plos.org)
September 15-20
Meet Associate Editor Melissa Vazquez Hernandez (mvazquezhernandez@plos.org)
September 16 - 17
Meet Editor in Chief Nonia Pariente (npariente@plos.org)
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