11/23/2021
Research Article
Balakumar Srinivasan, Sarbani Samaddar, Sourav Banerjee and co-workers reveal that RNA-dependent synergy between translation, degradation and miRISC remodeling is needed to achieve synaptic homeostasis during chronic changes in network activity. Also read the accompanying Primer by Ana Luisa Carvalho and Dominique Fernandes.
Image credit: pbio.3001432
Current Issue October 2021
11/18/2021
Research Article
Nina Kikel-Coury, Cody Smith and colleagues reveal that astrocyte-like cells termed cardiac nexus glia populate the heart, and that these cells are important for cardiac homeostasis, modulating heart rate and rhythm during development.
Image credit: pbio.3001444
11/18/2021
Update Article
A combination of psychophysics, computational modelling and fMRI, by Ambra Ferrari and Uta Noppeney, reveals novel insights into how the brain controls the binding of information across the senses, such as the voice and lip movements of a speaker.
Image credit: pbio.3001465
11/17/2021
Short Reports
The placozoan Trichoplax adhaerens is able to tolerate high levels of radiation and is resilient to DNA damage; Angelo Fortunato, Carlo Maley and co-authors reveal that exposure to X-rays triggers the extrusion of cell clusters which subsequently die, and that radiation exposure induces the overexpression of genes involved in DNA repair.
Image credit: pbio.3001471
11/16/2021
Methods and Resources
Enea Maffei, Aisylu Shaidullina, Alexander Harms and colleagues present the BASEL collection of phages that infect the model bacterium E. coli; this resource for the community is representative of natural E. coli phage diversity and has been extensively characterized phenotypically and genomically.
Image credit: pbio.3001424
11/16/2021
Research Article
Humans are altering biological systems at unprecedented rates and these alterations often have longer-term evolutionary impacts, such as the spread of resistance to pesticides and antibiotics. In this study, Troy Day, David McAdams and co-authors derive a simple mathematical criterion that determines when it pays to invest in strategies for controlling and managing evolutionary change.
Image credit: pbio.3001409
11/15/2021
Methods and Resources
This study presents a cloud-based toolbox for the flexible fusion of biodiversity records with remotely sensed and other environmental information that supports an assessment and accounting of such scale dependencies.
Image credit: pbio.3001460
11/12/2021
Perspective
There is a need for better models to improve preclinical testing of vaccines. This Perspective article argues that advanced mucosal human tissue models could present a solution to this pressing problem in the future.
Image credit: pbio.3001462
11/12/2021
Research Article
In all living organisms, cells must resist mechanical stress to survive; a study of Arabidopsis reveals that the candidate cell wall mechanoreceptor FERONIA and microtubules independently contribute to this mechanical feedback.
Image credit: pbio.3001454
11/12/2021
Research Article
This study reveals a temporal transcriptional program that diversifies neuronal subtype identity throughout the nervous system, in parallel with spatial patterning mechanisms.
Image credit: pbio.3001450
Raquel Lieberman discusses her work on the protein myocilin, implicated in glaucoma, but whose normal function remains unclear after over 20 years.
Susanna Bidgood explores the future of using poxviruses as versatile tools for cell biology research.
Rachel Harding proposes that open notebooks present an opportunity for researchers to showcase their work and rapidly advance science in their field
On the eve of the UN General Assembly meeting on TB, Christoph Grundner urged the need to consider basic research as an essential component of any future anti-TB strategy.
Norman Pace remembers the early days of what became known as "metagenomics," as experienced by the author during his development as a scientist.
Dec 6-10
Meet senior editor Ines Alvarez-Garcia
November 8-11
Meet senior editor Gabriel Gasque
November 2-4
Meet senior editor Roli Roberts
October 26-29
Meet associate editor Luke Smith
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