11/20/2023
Research Article
Understanding how individual memories are reactivated during sleep is essential in understanding memory consolidation. Jing Liu, Tatia Lee, Xiaoqing Hu and co-workers show that during human slow-wave sleep, unobtrusively re-presenting memory reminders elicits fine-grained item-specific neural representations that support the formation of long-term memories.
Image credit: pbio.3002399
Current Issue October 2023
11/20/2023
Research Article
How do mother centrioles generate only a single daughter centriole? Zachary Wilmott, Alain Goriely and Jordan Raff show that Polo-like kinase 4 (PLK4), the master regulator of centriole biogenesis, may form a simple two-component Turing-system to allow it to break symmetry and form a single site for daughter centriole assembly.
Image credit: pbio.3002391
11/20/2023
Research Article
Juan Quintana, Neil Mabbott and co-authors show that chronic brain infection with African trypanosomes induces broad meningeal responses resulting in the development of ectopic lymphoid aggregates containing autoreactive B cells; myelin basic protein is one of the autoantigens detected by autoreactive B cells, consistent with the cortical demyelination observed in experimental infections.
Image credit: pbio.3002389
11/20/2023
Research Article
Fear responses to threat represent an essential survival instinct. While previous work has focused primarily on the forebrain and limbic system, Hyoseo Lee, Hannah Weinberg-Wolf, Hae-Lim Lee, Andrii Rudenko, In-Jung Kim and colleagues examine the midbrain visual circuitry, identifying specific molecular mechanisms underlying its organization and fear-related behavioral function.
Image credit: pbio.3002386
11/20/2023
Research Article
Lavinia González Aparicio, Carolina López and co-workers show that non-standard viral genomes of the "copy-back" type (cbVGs) trigger translation inhibition and stress granule formation during virus infection. This is independent of the global antiviral response; instead, the translation inhibition induced by cbVGs leads to a reduction in viral protein expression.
Image credit: pbio.3002381
11/20/2023
Research Article
Influenza A virus infection can trigger condensation of host recycling endosomes adjacent to the endoplasmic reticulum. Sílvia Vale-Costa, Maria João Amorim and co-authors show that this a regulated process involving ATG9A, which facilitates the detachment of recycling endosomes from microtubules near the ER, revealing a novel role for ATG9A beyond autophagy.
Image credit: pbio.3002290
11/22/2023
Formal Comment
This article challenges a Perspective by Allison Byrne that called for the adoption of compassionate collection practices. Also read this response from the Perspective author.
Image credit: Flickr user Virginia State Park
11/21/2023
Essay
Patrick Keeling and Yana Eglit provide a series of technical diagrams to aid with teaching and communication on the complexity and diversity of microbial eukaryotes.
Image credit: pbio.3002395
11/20/2023
Perspective
How many species are there on Earth? Projections have ranged from the millions to the trillions. John Wiens looks at how a 2011 PLOS Biology study transformed this field and what is still to be done to find a definitive answer.
Image credit: John Wiens
11/16/2023
Perspective
In this Perspective article, BW Thuronyi, Erika DeBenedictis and Jeffrey Barrick argue that outdated methods narratives should be replaced with DNA sequence files when publishing life sciences research.
Image credit: BW Thuronyi
PLOS Biology is 20 and we are celebrating with a collection that contains articles that look back at landmark studies that we published, others that look past and future, and others discussing how publishing and open science have evolved and what is to come.
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This collection explores engineering strategies to help us adapt plants to a changing climate, including breeding techniques, genome engineering, synthetic biology and microbiome engineering.
The green collection explores biological solutions that could be applied to reduce CO2 emissions, get rid of non-degradable plastics, produce food in a sustainable manner or generate energy.
This collection explores potential solutions to mitigate the impacts of human activity on ocean ecosystems to minimize or reverse degradation.
To mark 200 years since the birth of Gregor Mendel, this collection looks back at the impact of his original research and asks how well it stands up to modern views on genetics.
December 2 - 6
Meet Senior Editor Ines Alvarez-Garcia (ialvarez-garcia@plos.org)
December 4 - 7
Meet Magazine Senior Editor Joanna Clarke (jclarke@plos.org)
December 12 - 15
Meet Senior Editor Roli Roberts (rroberts@plos.org)
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