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EBP1's Role in Plant Growth and Stress Response

October 19, 2018

EBP1's Role in Plant Growth and Stress Response

Chiyu Li, Xuanming Liu, Feng Yu and co-authors show that binding of the peptide ligand RALF1 to the plant receptor-like kinase FERONIA causes phosphorylation of EBP1 and promotes its nuclear-accumulation to regulate growth- and stress-related gene expression and provide negative feedback on RALF1 signaling.

Image credit: Chiyu Li and Feng Yu

Celebrate our 15th Anniversary! Tweet @PLOSBiology #PLOSBIO15

PLOS Biology's XV Collection

10/19/2018

research article

Fly Midgut Does Epithelial Polarity the Vertebrate Way

A developmental study in the fruit fly Drosophila melanogaster by Jia Chen, Aram-Christopher Sayadian, Nick Lowe, Holly Lovegrove and Daniel St Johnston shows that apical-basal polarity in the midgut epithelium is established by a different mechanism from other Drosophila epithelia, but more akin to that of vertebrate epithelia.

Image credit: pbio.3000041

Fly Midgut Does Epithelial Polarity the Vertebrate Way

Recently Published Articles

Current Issue

Current Issue September 2018

10/18/2018

Research Article

Glucose Switch Regulates Liver Cancer

Guang-Zhi Jin, Yajuan Zhang, Wen-Ming Cong, Guanzhen Yu, Weiwei Yang and colleagues find that the enzyme phosphoglucomutase 1 acts as a metabolic tumor suppressor that inhibits the progression of hepatocellular carcinoma by switching glycolysis to glycogen synthesis.

Image credit: RCSB PDB

Glucose Switch Regulates Liver Cancer

10/18/2018

Short Reports

Targeting Oxygen to Where it's Needed

Can oxygen delivery be directed to severely hypoxic tissues? Jason Boehme, Natacha Le Moan, Ana Krtolica, Emin Maltepe and co-authors show that an engineered hemoprotein with a high oxygen affinity can oxygenate failing sheep hearts without altering global oxygen exposure or triggering systemic toxicity.

Image credit: Jonathan A. Winger

Targeting Oxygen to Where it's Needed

10/18/2018

Methods and Resources

Running in the Wheel

Christine Häger, Lydia Keubler, André Bleich and co-workers propose the monitoring and clustering of voluntary wheel running as a novel tool to assess severity in laboratory mice, thereby enabling unbiased individual severity grading that contributes to 3R principles.

Running in the Wheel

Image credit: Rene Schwietzke, Flikr

10/17/2018

RESEARCH ARTICLE

Immune Systems Communicate in Spinal Cord Injury

Andrew Greenhalgh, Samuel David and colleagues show that in response to a CNS injury, peripheral immune cells infiltrate the lesion site and communicate directly with resident immune cells, suppressing their key functions and aiding recovery.

Immune Systems Communicate in Spinal Cord Injury

Image credit: pbio.2005264

10/16/2018

Short Reports

Nicotine Echoes down the Generations

Deirdre McCarthy, Pradeep Bhide and co-workers find that nicotine-induced changes in the methylation of mouse spermatozoal DNA are associated with alterations in behavioral and neurotransmitter phenotypes of multiple generations descending from the nicotine-exposed males

Nicotine Echoes down the Generations

Image credit: Pixabay

10/18/2018

research article

Detecting Pavlovian Conflict

Midfrontal cortex theta oscillations are linked to the detection of Pavlovian conflict, and the exertion of cognitive control to reduce the impact of maladaptive, Pavlovian biases. 

Detecting Pavlovian Conflict

Image credit: pbio.2005979

10/15/2018

short report 

Performance of the Human Cochlea

Electrophysiological recordings from the auditory nerve reveal sharper frequency tuning in humans than in animal models, but more limited phase-locking to the waveform of tones.

Performance of the Human Cochlea

Image credit: Flickr user monicasecas

10/15/2018

Research Article

Encoding Multimodal Sensory Information

Imaging populations of neurons in the crustacean stomatogastric nervous system reveals that different sensory modalities are represented by a combinatorial code of excitatory and inhibitory responses. 

Encoding Multimodal Sensory Information

Image credit: pbio.2004527

10/15/2018

editorial

Fifteen Years in, What Next for PLOS Biology?

As we celebrate our anniversary, the PLOS Biology editors discuss recent initiatives taken by the journal  and look ahead to the next fifteen years.

Fifteen Years in, What Next for PLOS Biology?

Image credit: pbio.3000049

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