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Wild Strawberry Sex

August 27, 2018

Wild Strawberry Sex

Jacob Tennessen, Tia-Lynn Ashman and co-workers find that the DNA sequence that determines the sex of wild strawberries has repeatedly jumped to new genomic locations during evolution, leading to increasingly differentiated sex chromosomes.

Image credit: Pixabay

Celebrate our 15th Anniversary! Tweet @PLOSBiology #PLOSBIO15

PLOS Biology's XV Collection

08/28/2018

research article

The Memory of Stress

Sander Govers, Abram Aertsen and co-workers show that protein aggregates in Escherichia coli tend to emerge in response to sub-lethal proteotoxic exposures, after which these asymmetrically inherited structures serve as stress-induced, epigenetic memory that protects their carrier cells against subsequent proteotoxic stress.

Image credit: pbio.2003853

The Memory of Stress

Recently Published Articles

Current Issue

Current Issue August 2018

08/27/2018

research article

What Determines ATP Levels?

Bryce Mendelsohn, Ken Nakamura and co-authors use a FRET-based high-throughput screen that measures ATPs levels in individual mammalian cells to identify genes that regulate ATP level, as well as genetic defects that are responsive to energy-based therapies such as coenzyme Q10 supplementation.

Image credit: pbio.2004624

What Determines ATP Levels?

08/28/2018

Community Page

Better Searching in PubMed

Nicolas Fiorini, Zhiyong Lu and co-authors present Best Match, a new relevance search algorithm for PubMed that allows readers to use machine learning to find articles that best match their needs.

Image credit: Flickr user: dullhunk

Better Searching in PubMed

08/29/2018

methods and resources

Sweetening HIV Vaccine

HIV-1 envelope protein is covered with unusual polysaccharides not normally produced by eukaryotic cells. Antibodies against the virus often require these sugars, potentially compromising manufacture of vaccine antigens, but Gabriel Byrne, Phillip Berman and colleagues' CRISPR-engineered high-mannose CHO cell line may offer a solution.

Sweetening HIV Vaccine

Image credit: pbio.2005817

08/29/2018

research article

How RIPK3 Expression is Lost in Cancer

Ayaz Najafov, Junying Yuan and co-workers use cell-based high-throughput screening and bioinformatics to identify BRAF and AXL as oncogenes that drive escape from necroptosis by reducing RIPK3 expression; sensitivity to necroptosis can be restored by targeting the oncogenes with drugs.

How RIPK3 Expression is Lost in Cancer

Image credit: PDB

08/31/2018

perspective

Corruption and Conservation

Craig Packer and Stephen Polasky propose that allocation of scarce conservation funding should consider the possibility that high-profile wildlife areas not only hold significant biodiversity value but may also be most vulnerable to leakage from local corruption.

Corruption and Conservation

Image credit: Flickr user: lhanaphotography

08/31/2018

research article

Pig Model of Lupus

Overexpression of leptin in transgenic pigs results in a phenotype bearing a remarkable resemblance to human systemic lupus erythromatosus (SLE), sharing multiple aspects of the disease.

Pig Model of Lupus

Image credit: pbio.2005354

08/28/2018

research article

Time and Space in the Hippocampus

Subnetworks segregated along the proximodistal axis of hippocampal CA1 and CA3 preferentially process spatial or non-spatial information.

Time and Space in the Hippocampus

Image credit: pbio.2006100

08/29/2018

Primer

Phase-Coding Memories

This Primer explores the implications of a new study that takes a significant step closer to understanding how information is maintained in mind by providing evidence for phase-coding in the human brain.

Phase-Coding Memories

Image credit: pbio.2003805

08/21/2018

research article

Competition Delays Drug Resistance in Malaria

Delayed emergence of drug-resistant malaria in sub-Saharan Africa may be caused by within-host competition between drug-sensitive and drug-resistant parasites.

Competition Delays Drug Resistance in Malaria

Image credit: nuzree, Pixabay

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