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Disentangling rice interactions with blast fungus

January 19, 2023

Disentangling rice interactions with blast fungus

Integrating genetic analyses of the pathogen rice blast fungus and its host plant, by Yu Sugihara, Sophien Kamoun, Ryohei Terauchi, Koki Fujisaki and co-authors, helps to disentangle the complex interactions that determine the outcome of plant-pathogen interactions.

Image credit: Akira Abe

PLOS Biologue

Community blog for PLOS Biology, PLOS Genetics and PLOS Computational Biology.

PLOS BIOLOGUE

01/19/2023

Research Article

What happens to the mammary gland after breast-feeding?

How are tissue remodeling, organ disassembly and the reversal of this process coordinated? Using the post-lactating mammary gland where a precisely orchestrated process shrinks the organ back to quiescence, Aleksandr Mironov, Matthew Fisher, Nasreen Akhtar and colleagues reveal that the small GTPase Rac1 plays a central role in restraining cell turnover, allowing reversibility from death if feeding recommences.

Image credit: Nasreen Akhtar and Matthew Fisher

What happens to the mammary gland after breast-feeding?

Recently Published Articles

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Current Issue

Current Issue December 2022

01/18/2023

Research Article

Membrane polarization dynamics in bacterial colonies

Membrane potential in bacterial systems has been shown to be dynamic and tightly related to survivability at the single cell level. This study of the the human pathogen Neisseria gonorrhoeae, by Marc Hennes, Berenike Maier and co-authors, shows that during bacterial colony development, the population transitions from heterogeneous to collective membrane polarization dynamics, marking the onset of habitat diversity.

Image credit: pbio.3001960

Membrane polarization dynamics in bacterial colonies

01/17/2023

Research Article

How do your hyphae grow?

A super-resolution imaging approach that maps cell wall thickness around live hyphae of the filamentous fungus Aspergillus nidulans, by Louis Chevalier, Arezki Boudaoud, Nicolas Minc and colleagues, reveals dynamic feedbacks between cell wall deformation and synthesis that promote steady hyphal growth as well as shape changes.

Image credit: pbio.3001981

How do your hyphae grow?

01/17/2023

Short Reports

Alpha clocks saccades during natural reading

Your eyes are saccading three to five times per second while reading this, but little is known about the neuronal mechanisms that coordinate the oculomotor and visual system. Yali Pan, Ole Jensen and colleagues show that alpha oscillations serve to time the processing between saccades and the visual system during natural reading.

Alpha clocks saccades during natural reading

Image credit: pbio.3001968

01/17/2023

Research Article

mRNA decay dynamics in the Drosophila embryo

Lauren Forbes Beadle, Jennifer Love, Magnus Rattray, Hilary Ashe and co-workers use modelling of total RNA-seq time series data across early Drosophila embryogenesis to provide estimates of mRNA half-lives; single-molecule imaging reveals that unstable mRNAs are more enriched in P-bodies, as are 3’ mRNA fragments.

mRNA decay dynamics in the Drosophila embryo

Image credit: Jennifer Love

01/17/2023

Research Article

Ferroportin inhibition by a minihepcidin

The iron exporter ferroportin is suppressed by hepcidin, an endogenous peptide hormone. The structure of human ferroportin bound to the hepcidin mimetic peptide PR73, by Azaan Saalim Wilbon, Jiemin Shen, Piotr Ruchala, Ming Zhou and Yaping Pan reveals interactions not seen in the hepcidin-ferroportin complex and provides a rationale for the enhanced affinity of PR73.

Ferroportin inhibition by a minihepcidin

Image credit: pbio.3001936

01/17/2023

Essay

​Open hardware: from DIY trend to global transformation

Open hardware solutions are increasingly being chosen by researchers as a strategy to improve access to technology for cutting-edge biology research. Tobias Wenzel discusses the current global reach and impact of open hardware.

​Open hardware: from DIY trend to global transformation

Image credit: pbio.3001931

01/17/2023

Research Article

Mechanisms of blindness

The transcription factors LHX2 and OTX2 collaborate to regulate the retinal pigmented epithelium differentiation program; a causal risk SNP contributes to age-related macular degeneration by altering binding of LHX2-OTX2 to the TRPM1 promoter.

Mechanisms of blindness

Image credit: Mazal Cohen-Gulkar

01/12/2023

Perspective

Strategic priorities for reproducibility reform

Increasing the reproducibility of research should be a top priority. This Perspective by Tony Ross-Hellauer argues that more work is needed to combine efforts and maximize our actions to enable true reproducibility reform.

Strategic priorities for reproducibility reform

Image credit: pbio.3001943

01/12/2023

Short Reports

Taste cells and immune surveillance

Mice lacking a regulator of M cell development showed impaired mucosal immune pathways in taste papillae and had heightened attraction to sweet and umami tastants, indicating crosstalk between taste cells and oral microbiome. Read the Primer.

Taste cells and immune surveillance

Image credit: pbio.3001647

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PLOS Biology | ISSN: 1545-7885 (online)