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Table of Contents: February 2017

While science has no place for the notion of a post-truth era, medical research has at times been susceptible to manipulation for non-scientific purposes. How should medical journals exemplify reliability in times of widespread competing interests and increasingly prominent health-related claims from unfiltered sources?

In this month's Editorial, the PLOS Medicine Editors recognize the members of our recently renewed editorial board and explore the editorial board's role in maintaining the journal's validity, relevance and vital connection to the medical research community.

Image Credit: geralt, Pixabay

Editorial

Essay

Evidence for scaling up HIV treatment in sub-Saharan Africa: A call for incorporating health system constraints

Evelinn Mikkelsen, Jan A. C. Hontelez, Maarten P. M. Jansen, Till Bärnighausen, Katharina Hauck, Kjell A. Johansson, Gesine Meyer-Rath, Mead Over, Sake J. de Vlas, Gert J. van der Wilt, Noor Tromp, Leon Bijlmakers, Rob M. P. M. Baltussen

Research Articles

Haemolysis in G6PD Heterozygous Females Treated with Primaquine for Plasmodium vivax Malaria: A Nested Cohort in a Trial of Radical Curative Regimens

Cindy S. Chu, Germana Bancone, Kerryn A. Moore, Htun Htun Win, Niramon Thitipanawan, Christina Po, Nongnud Chowwiwat, Rattanaporn Raksapraidee, Pornpimon Wilairisak, Aung Pyae Phyo, Lily Keereecharoen, Stéphane Proux, Prakaykaew Charunwatthana, François Nosten, Nicholas J. White

Performance and Cost-Effectiveness of Computed Tomography Lung Cancer Screening Scenarios in a Population-Based Setting: A Microsimulation Modeling Analysis in Ontario, Canada

Kevin ten Haaf, Martin C. Tammemägi, Susan J. Bondy, Carlijn M. van der Aalst, Sumei Gu, S. Elizabeth McGregor, Garth Nicholas, Harry J. de Koning, Lawrence F. Paszat

Related Articles

  1. Refining Lung Cancer Screening Criteria in the Era of Value-Based Medicine

Clinical applicability and cost of a 46-gene panel for genomic analysis of solid tumours: Retrospective validation and prospective audit in the UK National Health Service

Angela Hamblin, Sarah Wordsworth, Jilles M. Fermont, Suzanne Page, Kulvinder Kaur, Carme Camps, Pamela Kaisaki, Avinash Gupta, Denis Talbot, Mark Middleton, Shirley Henderson, Anthony Cutts, Dimitrios V. Vavoulis, Nick Housby, Ian Tomlinson, Jenny C. Taylor, Anna Schuh

Housing Improvements and Malaria Risk in Sub-Saharan Africa: A Multi-Country Analysis of Survey Data

Lucy S. Tusting, Christian Bottomley, Harry Gibson, Immo Kleinschmidt, Andrew J. Tatem, Steve W. Lindsay, Peter W. Gething

Delays and loss to follow-up before treatment of drug-resistant tuberculosis following implementation of Xpert MTB/RIF in South Africa: A retrospective cohort study

Helen Cox, Lindy Dickson-Hall, Norbert Ndjeka, Anja van’t Hoog, Alison Grant, Frank Cobelens, Wendy Stevens, Mark Nicol

Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial

Victoria K. Snowdon, Neil J. Lachlan, Anna M. Hoy, Patrick W. F. Hadoke, Scott I. Semple, Dilip Patel, Will Mungall, Timothy J. Kendall, Adrian Thomson, Ross J. Lennen, Maurits A. Jansen, Carmel M. Moran, Antonella Pellicoro, Prakash Ramachandran, Isaac Shaw, Rebecca L. Aucott, Thomas Severin, Rajnish Saini, Judy Pak, Denise Yates, Neelesh Dongre, Jeremy S. Duffield, David J. Webb, John P. Iredale, Peter C. Hayes, Jonathan A. Fallowfield