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Table of Contents

November 2017

In an Editorial published to coincide with World AIDS Day on December 1, Guest Editors Steven Deeks, Sharon Lewin and Linda-Gail Bekker discuss PLOS Medicine's Special Issue on Advances in HIV Prevention, Treatment and Cure. With global targets seeking to achieve an end to the HIV/AIDS epidemic, the authors describe some barriers that may prevent this from being achieved and highlight published research studies and discussion pieces that could illustrate paths to overcoming some of the ongoing challenges.

Image Credit: dfataustralianaid, Flickr

Editorial

The end of HIV: Still a very long way to go, but progress continues

Steven G. Deeks, Sharon R. Lewin, Linda-Gail Bekker

Essays

Sexual exploitation of unaccompanied migrant and refugee boys in Greece: Approaches to prevention

Julie Freccero, Dan Biswas, Audrey Whiting, Khaled Alrabe, Kim Thuy Seelinger

Perspectives

Reaching global HIV/AIDS goals: What got us here, won't get us there

Wafaa M. El-Sadr, Katherine Harripersaud, Miriam Rabkin

Prospects for passive immunity to prevent HIV infection

Lynn Morris, Nonhlanhla N. Mkhize

Closing the gaps in the HIV care continuum

Ruanne V. Barnabas, Connie Celum

The expanding epidemic of HIV-1 in the Russian Federation

Chris Beyrer, Andrea L. Wirtz, George O’Hara, Nolwenn Léon, Michel Kazatchkine

Policy Forum

Guidelines and Guidance

Core Outcome Set-STAndards for Development: The COS-STAD recommendations

Jamie J. Kirkham, Katherine Davis, Douglas G. Altman, Jane M. Blazeby, Mike Clarke, Sean Tunis, Paula R. Williamson

Collection Reviews

Human trafficking and exploitation: A global health concern

Cathy Zimmerman, Ligia Kiss

malERA: An updated research agenda for insecticide and drug resistance in malaria elimination and eradication

The malERA Refresh Consultative Panel on Insecticide and Drug Resistance

malERA: An updated research agenda for basic science and enabling technologies in malaria elimination and eradication

The malERA Refresh Consultative Panel on Basic Science and Enabling Technologies

malERA: An updated research agenda for characterising the reservoir and measuring transmission in malaria elimination and eradication

The malERA Refresh Consultative Panel on Characterising the Reservoir and Measuring Transmission

malERA: An updated research agenda for combination interventions and modelling in malaria elimination and eradication

The malERA Refresh Consultative Panel on Combination Interventions and Modelling

malERA: An updated research agenda for health systems and policy research in malaria elimination and eradication

The malERA Refresh Consultative Panel on Health Systems and Policy Research

malERA: An updated research agenda for diagnostics, drugs, vaccines, and vector control in malaria elimination and eradication

The malERA Refresh Consultative Panel on Tools for Malaria Elimination

malERA: An updated research agenda for malaria elimination and eradication

Regina N. Rabinovich, Chris Drakeley, Abdoulaye A. Djimde, B. Fenton Hall, Simon I. Hay, Janet Hemingway, David C. Kaslow, Abdisalan Noor, Fredros Okumu, Richard Steketee, Marcel Tanner, Timothy N. C. Wells, Maxine A. Whittaker, Elizabeth A. Winzeler, Dyann F. Wirth, Kate Whitfield, Pedro L. Alonso

Research Articles

Contemporary disengagement from antiretroviral therapy in Khayelitsha, South Africa: A cohort study

Samantha R. Kaplan, Christa Oosthuizen, Kathryn Stinson, Francesca Little, Jonathan Euvrard, Michael Schomaker, Meg Osler, Katherine Hilderbrand, Andrew Boulle, Graeme Meintjes

HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study

Timothy J. Henrich, Hiroyu Hatano, Oliver Bacon, Louise E. Hogan, Rachel Rutishauser, Alison Hill, Mary F. Kearney, Elizabeth M. Anderson, Susan P. Buchbinder, Stephanie E. Cohen, Mohamed Abdel-Mohsen, Christopher W. Pohlmeyer, Remi Fromentin, Rebecca Hoh, Albert Y. Liu, Joseph M. McCune, Jonathan Spindler, Kelly Metcalf-Pate, Kristen S. Hobbs, Cassandra Thanh, Erica A. Gibson, Daniel R. Kuritzkes, Robert F. Siliciano, Richard W. Price, Douglas D. Richman, Nicolas Chomont, Janet D. Siliciano, John W. Mellors, Steven A. Yukl, Joel N. Blankson, Teri Liegler, Steven G. Deeks

Effectiveness of a combination strategy for linkage and retention in adult HIV care in Swaziland: The Link4Health cluster randomized trial

Margaret L. McNairy, Matthew R. Lamb, Averie B. Gachuhi, Harriet Nuwagaba-Biribonwoha, Sean Burke, Sikhathele Mazibuko, Velephi Okello, Peter Ehrenkranz, Ruben Sahabo, Wafaa M. El-Sadr

HIV prevalence and behavioral and psychosocial factors among transgender women and cisgender men who have sex with men in 8 African countries: A cross-sectional analysis

Tonia Poteat, Benjamin Ackerman, Daouda Diouf, Nuha Ceesay, Tampose Mothopeng, Ky-Zerbo Odette, Seni Kouanda, Henri Gautier Ouedraogo, Anato Simplice, Abo Kouame, Zandile Mnisi, Gift Trapence, L. Leigh Ann van der Merwe, Vicente Jumbe, Stefan Baral

Cardiovascular disease (CVD) and chronic kidney disease (CKD) event rates in HIV-positive persons at high predicted CVD and CKD risk: A prospective analysis of the D:A:D observational study

Mark A. Boyd, Amanda Mocroft, Lene Ryom, Antonella d’Arminio Monforte, Caroline Sabin, Wafaa M. El-Sadr, Camilla Ingrid Hatleberg, Stephane De Wit, Rainer Weber, Eric Fontas, Andrew Phillips, Fabrice Bonnet, Peter Reiss, Jens Lundgren, Matthew Law

Validity of a minimally invasive autopsy for cause of death determination in maternal deaths in Mozambique: An observational study

Paola Castillo, Juan Carlos Hurtado, Miguel J. Martínez, Dercio Jordao, Lucilia Lovane, Mamudo R. Ismail, Carla Carrilho, Cesaltina Lorenzoni, Fabiola Fernandes, Sibone Mocumbi, Zara Onila Jaze, Flora Mabota, Anelsio Cossa, Inacio Mandomando, Pau Cisteró, Alfredo Mayor, Mireia Navarro, Isaac Casas, Jordi Vila, Maria Maixenchs, Khátia Munguambe, Ariadna Sanz, Llorenç Quintó, Eusebio Macete, Pedro Alonso, Quique Bassat, Jaume Ordi, Clara Menéndez

Perinatal mortality associated with induction of labour versus expectant management in nulliparous women aged 35 years or over: An English national cohort study

Hannah E. Knight, David A. Cromwell, Ipek Gurol-Urganci, Katie Harron, Jan H. van der Meulen, Gordon C. S. Smith

Bioequivalence between innovator and generic tacrolimus in liver and kidney transplant recipients: A randomized, crossover clinical trial

Rita R. Alloway, Alexander A. Vinks, Tsuyoshi Fukuda, Tomoyuki Mizuno, Eileen C. King, Yuanshu Zou, Wenlei Jiang, E. Steve Woodle, Simon Tremblay, Jelena Klawitter, Jost Klawitter, Uwe Christians

Related Articles

Virological response and resistance among HIV-infected children receiving long-term antiretroviral therapy without virological monitoring in Uganda and Zimbabwe: Observational analyses within the randomised ARROW trial

Alexander J. Szubert, Andrew J. Prendergast, Moira J. Spyer, Victor Musiime, Philippa Musoke, Mutsa Bwakura-Dangarembizi, Patricia Nahirya-Ntege, Margaret J. Thomason, Emmanuel Ndashimye, Immaculate Nkanya, Oscar Senfuma, Boniface Mudenge, Nigel Klein, Diana M. Gibb, A. Sarah Walker, the ARROW Trial Team

A combination intervention strategy to improve linkage to and retention in HIV care following diagnosis in Mozambique: A cluster-randomized study

Batya Elul, Matthew R. Lamb, Maria Lahuerta, Fatima Abacassamo, Laurence Ahoua, Stephanie A. Kujawski, Maria Tomo, Ilesh Jani

Treatment guidelines and early loss from care for people living with HIV in Cape Town, South Africa: A retrospective cohort study

Ingrid T. Katz, Richard Kaplan, Garrett Fitzmaurice, Dominick Leone, David R. Bangsberg, Linda-Gail Bekker, Catherine Orrell

Safety, pharmacokinetics, and immunological activities of multiple intravenous or subcutaneous doses of an anti-HIV monoclonal antibody, VRC01, administered to HIV-uninfected adults: Results of a phase 1 randomized trial

Kenneth H. Mayer, Kelly E. Seaton, Yunda Huang, Nicole Grunenberg, Abby Isaacs, Mary Allen, Julie E. Ledgerwood, Ian Frank, Magdalena E. Sobieszczyk, Lindsey R. Baden, Benigno Rodriguez, Hong Van Tieu, Georgia D. Tomaras, Aaron Deal, Derrick Goodman, Robert T. Bailer, Guido Ferrari, Ryan Jensen, John Hural, Barney S. Graham, John R. Mascola, Lawrence Corey, David C. Montefiori, on behalf of the HVTN 104 Protocol Team, and the NIAID HIV Vaccine Trials Network

Postmenopausal hormone therapy and risk of stroke: A pooled analysis of data from population-based cohort studies

Germán D. Carrasquilla, Paolo Frumento, Anita Berglund, Christer Borgfeldt, Matteo Bottai, Chiara Chiavenna, Mats Eliasson, Gunnar Engström, Göran Hallmans, Jan-Håkan Jansson, Patrik K. Magnusson, Peter M. Nilsson, Nancy L. Pedersen, Alicja Wolk, Karin Leander

HIV self-testing among female sex workers in Zambia: A cluster randomized controlled trial

Michael M. Chanda, Katrina F. Ortblad, Magdalene Mwale, Steven Chongo, Catherine Kanchele, Nyambe Kamungoma, Andrew Fullem, Caitlin Dunn, Leah G. Barresi, Guy Harling, Till Bärnighausen, Catherine E. Oldenburg

HIV pre-exposure prophylaxis and early antiretroviral treatment among female sex workers in South Africa: Results from a prospective observational demonstration project

Robyn Eakle, Gabriela B. Gomez, Niven Naicker, Rutendo Bothma, Judie Mbogua, Maria A. Cabrera Escobar, Elaine Saayman, Michelle Moorhouse, W. D. Francois Venter, Helen Rees, on behalf of the TAPS Demonstration Project Team

The value of confirmatory testing in early infant HIV diagnosis programmes in South Africa: A cost-effectiveness analysis

Lorna Dunning, Jordan A. Francke, Divya Mallampati, Rachel L. MacLean, Martina Penazzato, Taige Hou, Landon Myer, Elaine J. Abrams, Rochelle P. Walensky, Valériane Leroy, Kenneth A. Freedberg, Andrea Ciaranello

The US President's Malaria Initiative, Plasmodium falciparum transmission and mortality: A modelling study

Peter Winskill, Hannah C. Slater, Jamie T. Griffin, Azra C. Ghani, Patrick G. T. Walker

Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort

Tom A. Yates, Laurie A. Tomlinson, Krishnan Bhaskaran, Sinead Langan, Sara Thomas, Liam Smeeth, Ian J. Douglas

Direct provision versus facility collection of HIV self-tests among female sex workers in Uganda: A cluster-randomized controlled health systems trial

Katrina Ortblad, Daniel Kibuuka Musoke, Thomson Ngabirano, Aidah Nakitende, Jonathan Magoola, Prossy Kayiira, Geoffrey Taasi, Leah G. Barresi, Jessica E. Haberer, Margaret A. McConnell, Catherine E. Oldenburg, Till Bärnighausen

Respondent-driven sampling for identification of HIV- and HCV-infected people who inject drugs and men who have sex with men in India: A cross-sectional, community-based analysis

Sunil S. Solomon, Allison M. McFall, Gregory M. Lucas, Aylur K. Srikrishnan, Muniratnam S. Kumar, Santhanam Anand, Thomas C. Quinn, David D. Celentano, Shruti H. Mehta

Extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy: A case study

Nathan W. Cummins, Stacey Rizza, Mark R. Litzow, Stephane Hua, Guinevere Q. Lee, Kevin Einkauf, Tae-Wook Chun, Frank Rhame, Jason V. Baker, Michael P. Busch, Nicolas Chomont, Patrick G. Dean, Rémi Fromentin, Ashley T. Haase, Dylan Hampton, Sheila M. Keating, Steven M. Lada, Tzong-Hae Lee, Sekar Natesampillai, Douglas D. Richman, Timothy W. Schacker, Stephen Wietgrefe, Xu G. Yu, Joseph D. Yao, John Zeuli, Mathias Lichterfeld, Andrew D. Badley

Treatment eligibility and retention in clinical HIV care: A regression discontinuity study in South Africa

Jacob Bor, Matthew P. Fox, Sydney Rosen, Atheendar Venkataramani, Frank Tanser, Deenan Pillay, Till Bärnighausen