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October 2020

Examining the global situation in child health more than 5 years into the trajectory towards the 2030 Sustainable Development Goals, several concerns emerge – the field remains fragmented, with limited actions in countries to develop integrated strategies for reproductive, maternal, child and newborn health, or for inclusion of adolescent health within national plans. The gains in early child health painstakingly achieved since 2000 are at risk of slowing down and losing priority, and the world needs to redouble its efforts to do better. For this reason, PLOS Medicine is planning a Special Issue devoted to research and practice in the area of Global Child and Adolescent Health, to be published in 2021.

In this month’s Editorial, the Editors of the forthcoming Special Issue discuss the current and future prospects for young people’s health globally.

Image Credit: Free-Photos, Pixabay (CC0)

Editorial

Revisiting child and adolescent health in the context of the Sustainable Development Goals

Zulfiqar A. Bhutta, Kathryn M. Yount, Quique Bassat, Artur A. Arikainen

Policy Forum

Collection Review

The intersection of genomics and big data with public health: Opportunities for precision public health

Muin J. Khoury, Gregory L. Armstrong, Rebecca E. Bunnell, Juliana Cyril, Michael F. Iademarco

Research Articles

Seroprevalence of SARS-CoV-2 antibodies in people with an acute loss in their sense of smell and/or taste in a community-based population in London, UK: An observational cohort study

Janine Makaronidis, Jessica Mok, Nyaladzi Balogun, Cormac G. Magee, Rumana Z. Omar, Alisia Carnemolla, Rachel L. Batterham

Circulating tumour DNA in metastatic breast cancer to guide clinical trial enrolment and precision oncology: A cohort study

Andjelija Zivanovic Bujak, Chen-Fang Weng, Maria João Silva, Miriam Yeung, Louisa Lo, Sarah Ftouni, Cassandra Litchfield, Yi-An Ko, Keilly Kuykhoven, Courtney Van Geelen, Sushma Chandrashekar, Mark A. Dawson, Sherene Loi, Stephen Q. Wong, Sarah-Jane Dawson

Association of technologically assisted integrated care with clinical outcomes in type 2 diabetes in Hong Kong using the prospective JADE Program: A retrospective cohort analysis

Lee-Ling Lim, Eric S. H. Lau, Risa Ozaki, Harriet Chung, Amy W. C. Fu, Wendy Chan, Alice P. S. Kong, Ronald C. W. Ma, Wing-Yee So, Elaine Chow, Kitty K. T. Cheung, Tiffany Yau, C. C. Chow, Vanessa Lau, Rebecca Yue, Shek Ng, Benny Zee, William Goggins, Brian Oldenburg, Philip M. Clarke, Maggie Lau, Rebecca Wong, C. C. Tsang, Edward W. Gregg, Hongjiang Wu, Peter C. Y. Tong, Gary T. C. Ko, Andrea O. Y. Luk, Juliana C. N. Chan

Association between prehospital time and outcome of trauma patients in 4 Asian countries: A cross-national, multicenter cohort study

Chi-Hsin Chen, Sang Do Shin, Jen-Tang Sun, Sabariah Faizah Jamaluddin, Hideharu Tanaka, Kyoung Jun Song, Kentaro Kajino, Akio Kimura, Edward Pei-Chuan Huang, Ming-Ju Hsieh, Matthew Huei-Ming Ma, Wen-Chu Chiang

Midwifery continuity of care versus standard maternity care for women at increased risk of preterm birth: A hybrid implementation–effectiveness, randomised controlled pilot trial in the UK

Cristina Fernandez Turienzo, Debra Bick, Annette L. Briley, Mary Bollard, Kirstie Coxon, Pauline Cross, Sergio A. Silverio, Claire Singh, Paul T. Seed, Rachel M. Tribe, Andrew H. Shennan, Jane Sandall, on behalf of the POPPIE Pilot Collaborative Group

The impact of continuous quality improvement on coverage of antenatal HIV care tests in rural South Africa: Results of a stepped-wedge cluster-randomised controlled implementation trial

H. Manisha Yapa, Jan-Walter De Neve, Terusha Chetty, Carina Herbst, Frank A. Post, Awachana Jiamsakul, Pascal Geldsetzer, Guy Harling, Wendy Dhlomo-Mphatswe, Mosa Moshabela, Philippa Matthews, Osondu Ogbuoji, Frank Tanser, Dickman Gareta, Kobus Herbst, Deenan Pillay, Sally Wyke, Till Bärnighausen

Genetics of height and risk of atrial fibrillation: A Mendelian randomization study

Michael G. Levin, Renae Judy, Dipender Gill, Marijana Vujkovic, Shefali S. Verma, Yuki Bradford, Regeneron Genetics Center, Marylyn D. Ritchie, Matthew C. Hyman, Saman Nazarian, Daniel J. Rader, Benjamin F. Voight, Scott M. Damrauer

Socioeconomic level and associations between heat exposure and all-cause and cause-specific hospitalization in 1,814 Brazilian cities: A nationwide case-crossover study

Rongbin Xu, Qi Zhao, Micheline S. Z. S. Coelho, Paulo H. N. Saldiva, Michael J. Abramson, Shanshan Li, Yuming Guo

Trends in prevalence of acute stroke impairments: A population-based cohort study using the South London Stroke Register

Amanda Clery, Ajay Bhalla, Anthony G. Rudd, Charles D. A. Wolfe, Yanzhong Wang

Impact of providing free HIV self-testing kits on frequency of testing among men who have sex with men and their sexual partners in China: A randomized controlled trial

Ci Zhang, Deborah Koniak-Griffin, Han-Zhu Qian, Lloyd A. Goldsamt, Honghong Wang, Mary-Lynn Brecht, Xianhong Li

Neurodevelopmental multimorbidity and educational outcomes of Scottish schoolchildren: A population-based record linkage cohort study

Michael Fleming, Ehsan E. Salim, Daniel F. Mackay, Angela Henderson, Deborah Kinnear, David Clark, Albert King, James S. McLay, Sally-Ann Cooper, Jill P. Pell

Universal third-trimester ultrasonic screening using fetal macrosomia in the prediction of adverse perinatal outcome: A systematic review and meta-analysis of diagnostic test accuracy

Alexandros A. Moraitis, Norman Shreeve, Ulla Sovio, Peter Brocklehurst, Alexander E. P. Heazell, Jim G. Thornton, Stephen C. Robson, Aris Papageorghiou, Gordon C. Smith

Evaluation of a pharmacist-led actionable audit and feedback intervention for improving medication safety in UK primary care: An interrupted time series analysis

Niels Peek, Wouter T. Gude, Richard N. Keers, Richard Williams, Evangelos Kontopantelis, Mark Jeffries, Denham L. Phipps, Benjamin Brown, Anthony J. Avery, Darren M. Ashcroft

Health outcomes and cost-effectiveness of diversion programs for low-level drug offenders: A model-based analysis

Cora L. Bernard, Isabelle J. Rao, Konner K. Robison, Margaret L. Brandeau

The potential health impact of restricting less-healthy food and beverage advertising on UK television between 05.30 and 21.00 hours: A modelling study

Oliver T. Mytton, Emma Boyland, Jean Adams, Brendan Collins, Martin O’Connell, Simon J. Russell, Kate Smith, Rebekah Stroud, Russell M. Viner, Linda J. Cobiac

Serially assessed bisphenol A and phthalate exposure and association with kidney function in children with chronic kidney disease in the US and Canada: A longitudinal cohort study

Melanie H. Jacobson, Yinxiang Wu, Mengling Liu, Teresa M. Attina, Mrudula Naidu, Rajendiran Karthikraj, Kurunthachalam Kannan, Bradley A. Warady, Susan Furth, Suzanne Vento, Howard Trachtman, Leonardo Trasande

Risk of disease and willingness to vaccinate in the United States: A population-based survey

Bert Baumgaertner, Benjamin J. Ridenhour, Florian Justwan, Juliet E. Carlisle, Craig R. Miller

Developing and validating subjective and objective risk-assessment measures for predicting mortality after major surgery: An international prospective cohort study

Danny J. N. Wong, Steve Harris, Arun Sahni, James R. Bedford, Laura Cortes, Richard Shawyer, Andrew M. Wilson, Helen A. Lindsay, Doug Campbell, Scott Popham, Lisa M. Barneto, Paul S. Myles, SNAP-2: EPICCS collaborators, S. Ramani Moonesinghe

Pulmonary vascular dysfunction among people aged over 65 years in the community in the Atherosclerosis Risk In Communities (ARIC) Study: A cross-sectional analysis

Kanako Teramoto, Mário Santos, Brian Claggett, Jenine E. John, Scott D. Solomon, Dalane Kitzman, Aaron R. Folsom, Mary Cushman, Kunihiro Matsushita, Hicham Skali, Amil M. Shah

Time trends and prescribing patterns of opioid drugs in UK primary care patients with non-cancer pain: A retrospective cohort study

Meghna Jani, Belay Birlie Yimer, Therese Sheppard, Mark Lunt, William G. Dixon

The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis

Ju-Sheng Zheng, Jian’an Luan, Eleni Sofianopoulou, Stephen J. Sharp, Felix R. Day, Fumiaki Imamura, Thomas E. Gundersen, Luca A. Lotta, Ivonne Sluijs, Isobel D. Stewart, Rupal L. Shah, Yvonne T. van der Schouw, Eleanor Wheeler, Eva Ardanaz, Heiner Boeing, Miren Dorronsoro, Christina C. Dahm, Niki Dimou, Douae El-Fatouhi, Paul W. Franks, Guy Fagherazzi, Sara Grioni, José María Huerta, Alicia K. Heath, Louise Hansen, Mazda Jenab, Paula Jakszyn, Rudolf Kaaks, Tilman Kühn, Kay-Tee Khaw, Nasser Laouali, Giovanna Masala, Peter M. Nilsson, Kim Overvad, Anja Olsen, Salvatore Panico, J. Ramón Quirós, Olov Rolandsson, Miguel Rodríguez-Barranco, Carlotta Sacerdote, Annemieke M. W. Spijkerman, Tammy Y. N. Tong, Rosario Tumino, Konstantinos K. Tsilidis, John Danesh, Elio Riboli, Adam S. Butterworth, Claudia Langenberg, Nita G. Forouhi, Nicholas J. Wareham

The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis

Andria Mousa, Abdullah Al-Taiar, Nicholas M. Anstey, Cyril Badaut, Bridget E. Barber, Quique Bassat, Joseph D. Challenger, Aubrey J. Cunnington, Dibyadyuti Datta, Chris Drakeley, Azra C. Ghani, Victor R. Gordeuk, Matthew J. Grigg, Pierre Hugo, Chandy C. John, Alfredo Mayor, Florence Migot-Nabias, Robert O. Opoka, Geoffrey Pasvol, Claire Rees, Hugh Reyburn, Eleanor M. Riley, Binal N. Shah, Antonio Sitoe, Colin J. Sutherland, Philip E. Thuma, Stefan A. Unger, Firmine Viwami, Michael Walther, Christopher J. M. Whitty, Timothy William, Lucy C. Okell

Differential association of air pollution exposure with neonatal and postneonatal mortality in England and Wales: A cohort study

Sarah J. Kotecha, W. John Watkins, John Lowe, Jonathan Grigg, Sailesh Kotecha

Rapid Epidemiological Analysis of Comorbidities and Treatments as risk factors for COVID-19 in Scotland (REACT-SCOT): A population-based case-control study

Paul M. McKeigue, Amanda Weir, Jen Bishop, Stuart J. McGurnaghan, Sharon Kennedy, David McAllister, Chris Robertson, Rachael Wood, Nazir Lone, Janet Murray, Thomas M. Caparrotta, Alison Smith-Palmer, David Goldberg, Jim McMenamin, Colin Ramsay, Sharon Hutchinson, Helen M. Colhoun, on behalf of Public Health Scotland COVID-19 Health Protection Study Group

Predictive value of pulse oximetry for mortality in infants and children presenting to primary care with clinical pneumonia in rural Malawi: A data linkage study

Tim Colbourn, Carina King, James Beard, Tambosi Phiri, Malizani Mdala, Beatiwel Zadutsa, Charles Makwenda, Anthony Costello, Norman Lufesi, Charles Mwansambo, Bejoy Nambiar, Shubhada Hooli, Neil French, Naor Bar Zeev, Shamim Ahmad Qazi, Yasir Bin Nisar, Eric D. McCollum

Effectiveness of the 23-valent pneumococcal polysaccharide vaccine against vaccine serotype pneumococcal pneumonia in adults: A case-control test-negative design study

Hannah Lawrence, Harry Pick, Vadsala Baskaran, Priya Daniel, Chamira Rodrigo, Deborah Ashton, Rochelle C. Edwards-Pritchard, Carmen Sheppard, Seyi D. Eletu, David Litt, Norman K. Fry, Samuel Rose, Caroline Trotter, Tricia M. McKeever, Wei Shen Lim

Medicalization of female genital cutting in Malaysia: A mixed methods study

Abdul Rashid, Yufu Iguchi, Siti Nur Afiqah

The diagnostic performance of CA125 for the detection of ovarian and non-ovarian cancer in primary care: A population-based cohort study

Garth Funston, Willie Hamilton, Gary Abel, Emma J. Crosbie, Brian Rous, Fiona M. Walter

Defining remission of type 2 diabetes in research studies: A systematic scoping review

Mireille Captieux, Regina Prigge, Sarah Wild, Bruce Guthrie

Acute kidney injury associated with COVID-19: A retrospective cohort study

Nitin V. Kolhe, Richard J. Fluck, Nicholas M. Selby, Maarten W. Taal

Metabolically healthy obesity, transition to unhealthy metabolic status, and vascular disease in Chinese adults: A cohort study

Meng Gao, Jun Lv, Canqing Yu, Yu Guo, Zheng Bian, Ruotong Yang, Huaidong Du, Ling Yang, Yiping Chen, Zhongxiao Li, Xi Zhang, Junshi Chen, Lu Qi, Zhengming Chen, Tao Huang, Liming Li, for the China Kadoorie Biobank (CKB) Collaborative Group

Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium

Signe Hässler, Delphine Bachelet, Julianne Duhaze, Natacha Szely, Aude Gleizes, Salima Hacein-Bey Abina, Orhan Aktas, Michael Auer, Jerôme Avouac, Mary Birchler, Yoram Bouhnik, Olivier Brocq, Dorothea Buck-Martin, Guillaume Cadiot, Franck Carbonnel, Yehuda Chowers, Manuel Comabella, Tobias Derfuss, Niek De Vries, Naoimh Donnellan, Abiba Doukani, Michael Guger, Hans-Peter Hartung, Eva Kubala Havrdova, Bernhard Hemmer, Tom Huizinga, Kathleen Ingenhoven, Poul Erik Hyldgaard-Jensen, Elizabeth C. Jury, Michael Khalil, Bernd Kieseier, Anna Laurén, Raija Lindberg, Amy Loercher, Enrico Maggi, Jessica Manson, Claudia Mauri, Badreddine Mohand Oumoussa, Xavier Montalban, Maria Nachury, Petra Nytrova, Christophe Richez, Malin Ryner, Finn Sellebjerg, Claudia Sievers, Dan Sikkema, Martin Soubrier, Sophie Tourdot, Caroline Trang, Alessandra Vultaggio, Clemens Warnke, Sebastian Spindeldreher, Pierre Dönnes, Timothy P. Hickling, Agnès Hincelin Mery, Matthieu Allez, Florian Deisenhammer, Anna Fogdell-Hahn, Xavier Mariette, Marc Pallardy, Philippe Broët, ABIRISK consortium

Primary healthcare expansion and mortality in Brazil’s urban poor: A cohort analysis of 1.2 million adults

Thomas Hone, Valeria Saraceni, Claudia Medina Coeli, Anete Trajman, Davide Rasella, Christopher Millett, Betina Durovni

Corrections

Correction: Social distancing to slow the US COVID-19 epidemic: Longitudinal pretest–posttest comparison group study

Mark J. Siedner, Guy Harling, Zahra Reynolds, Rebecca F. Gilbert, Sebastien Haneuse, Atheendar S. Venkataramani, Alexander C. Tsai

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