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Table of Contents

July 2010

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HIV in Maternal and Child Heath: Concurrent crises demand cooperation.
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In our Editorial this month the PLoS Medicine editors argue that the time has come to integrate prevention and treatment of HIV into maternal and child health care programs. A recent analysis of maternal deaths worldwide cited in the Editorial revealed that without the HIV epidemic there would have been an estimated 61,400 fewer maternal deaths in 2008. Although tackling HIV is a priority within the Millennium Development Goals (MDGs), it is not specifically included in the MDGs for reducing child mortality and improving maternal health. A more integrated approach is needed, say the editors, recognizing maternal and child health and HIV as concurrent crises. The Editorial concludes that "the time has come to stop tackling infectious diseases, specifically HIV, in isolation from other health goals, and instead to examine the opportunities for integrating and scaling up delivery of HIV prevention and treatment services within the context of maternal and child health care."

Image Credit: Narith5 at flickr.com

Editorial

HIV in Maternal and Child Heath: Concurrent Crises Demand Cooperation

The PLoS Medicine Editors

PLOS Medicine: published July 27, 2010 | https://doi.org/10.1371/journal.pmed.1000311

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  3. Sub-Saharan Africa's Mothers, Newborns, and Children: How Many Lives Could Be Saved with Targeted Health Interventions?

Essays

Improving Implementation: Building Research Capacity in Maternal, Neonatal, and Child Health in Africa

James Whitworth, Nelson K. Sewankambo, Valerie A. Snewin

PLOS Medicine: published July 6, 2010 | https://doi.org/10.1371/journal.pmed.1000299

Evidence-Based Priority Setting for Health Care and Research: Tools to Support Policy in Maternal, Neonatal, and Child Health in Africa

Igor Rudan, Lydia Kapiriri, Mark Tomlinson, Manuela Balliet, Barney Cohen, Mickey Chopra

PLOS Medicine: published July 13, 2010 | https://doi.org/10.1371/journal.pmed.1000308

Health in Action

Improving Prevention of Mother-to-Child Transmission of HIV Care and Related Services in Eastern Rwanda

Younsook Lim, Jim Yong Kim, Michael Rich, Sara Stulac, Jean Bosco Niyonzima, Mary C. Smith Fawzi, Rose Gahire, Martha Mukaminega, Marya Getchell, Curtis W. Peterson, Paul E. Farmer, Agnès Binagwaho

PLOS Medicine: published July 20, 2010 | https://doi.org/10.1371/journal.pmed.1000302

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Policy Forums

HIV Testing for Children in Resource-Limited Settings: What Are We Waiting For?

Scott Kellerman, Shaffiq Essajee

PLOS Medicine: published July 20, 2010 | https://doi.org/10.1371/journal.pmed.1000285

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Financing Maternal and Child Health—What Are the Limitations in Estimating Donor Flows and Resource Needs?

Marco Schäferhoff, Christina Schrade, Gavin Yamey

PLOS Medicine: published July 6, 2010 | https://doi.org/10.1371/journal.pmed.1000305

Left to Their Own Devices: Breakdowns in United States Medical Device Premarket Review

Jonas Zajac Hines, Peter Lurie, Eunice Yu, Sidney Wolfe

PLOS Medicine: published July 13, 2010 | https://doi.org/10.1371/journal.pmed.1000280

Learning Forum

Three Adult Cases of Listeria monocytogenes Meningitis in Vietnam

Tran Thi Hong Chau, James I. Campbell, Constance Schultsz, Nguyen Van Vinh Chau, To Song Diep, Stephen Baker, Nguyen Tran Chinh, Jeremy J. Farrar, H. Rogier van Doorn

PLOS Medicine: published July 27, 2010 | https://doi.org/10.1371/journal.pmed.1000306

Research Articles

Social Relationships and Mortality Risk: A Meta-analytic Review

Julianne Holt-Lunstad, Timothy B. Smith, J. Bradley Layton

PLOS Medicine: published July 27, 2010 | https://doi.org/10.1371/journal.pmed.1000316

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Association of Early Repolarization Pattern on ECG with Risk of Cardiac and All-Cause Mortality: A Population-Based Prospective Cohort Study (MONICA/KORA)

Moritz F. Sinner, Wibke Reinhard, Martina Müller, Britt-Maria Beckmann, Eimo Martens, Siegfried Perz, Arne Pfeufer, Janina Winogradow, Klaus Stark, Christa Meisinger, H.-Erich Wichmann, Annette Peters, Günter A. J. Riegger, Gerhard Steinbeck, Christian Hengstenberg, Stefan Kääb

PLOS Medicine: published July 27, 2010 | https://doi.org/10.1371/journal.pmed.1000314

A Model for the Roll-Out of Comprehensive Adult Male Circumcision Services in African Low-Income Settings of High HIV Incidence: The ANRS 12126 Bophelo Pele Project

Pascale Lissouba, Dirk Taljaard, Dino Rech, Sean Doyle, Daniel Shabangu, Cynthia Nhlapo, Josephine Otchere-Darko, Thabo Mashigo, Caitlin Matson, David Lewis, Scott Billy, Bertran Auvert

PLOS Medicine: published July 20, 2010 | https://doi.org/10.1371/journal.pmed.1000309

Estimating the Number of Paediatric Fevers Associated with Malaria Infection Presenting to Africa's Public Health Sector in 2007

Peter W. Gething, Viola C. Kirui, Victor A. Alegana, Emelda A. Okiro, Abdisalan M. Noor, Robert W. Snow

PLOS Medicine: published July 6, 2010 | https://doi.org/10.1371/journal.pmed.1000301

Stable and Unstable Malaria Hotspots in Longitudinal Cohort Studies in Kenya

Philip Bejon, Thomas N. Williams, Anne Liljander, Abdisalan M. Noor, Juliana Wambua, Edna Ogada, Ally Olotu, Faith H. A. Osier, Simon I. Hay, Anna Färnert, Kevin Marsh

PLOS Medicine: published July 6, 2010 | https://doi.org/10.1371/journal.pmed.1000304

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  1. Correction: Stable and Unstable Malaria Hotspots in Longitudinal Cohort Studies in Kenya

A Six-Gene Signature Predicts Survival of Patients with Localized Pancreatic Ductal Adenocarcinoma

Jeran K. Stratford, David J. Bentrem, Judy M. Anderson, Cheng Fan, Keith A. Volmar, J. S. Marron, Elizabeth D. Routh, Laura S. Caskey, Jonathan C. Samuel, Channing J. Der, Leigh B. Thorne, Benjamin F. Calvo, Hong Jin Kim, Mark S. Talamonti, Christine A. Iacobuzio-Donahue, Michael A. Hollingsworth, Charles M. Perou, Jen Jen Yeh

PLOS Medicine: published July 13, 2010 | https://doi.org/10.1371/journal.pmed.1000307

Integrative Genomic Analyses Identify BRF2 as a Novel Lineage-Specific Oncogene in Lung Squamous Cell Carcinoma

William W. Lockwood, Raj Chari, Bradley P. Coe, Kelsie L. Thu, Cathie Garnis, Chad A. Malloff, Jennifer Campbell, Ariane C. Williams, Dorothy Hwang, Chang-Qi Zhu, Timon P. H. Buys, John Yee, John C. English, Calum MacAulay, Ming-Sound Tsao, Adi F. Gazdar, John D. Minna, Stephen Lam, Wan L. Lam

PLOS Medicine: published July 27, 2010 | https://doi.org/10.1371/journal.pmed.1000315