Table of Contents: November 2006

The cover image is derived from photographs in the paper by Patrick Duffy and colleagues in which it is established that a younger woman in her first pregnancy who develops placental malaria is more likely than other mothers to suffer from preeclampsia, which can have severe consequences for both her and her child.

Image Credit: Cover design by Natalie Davis, Public Library of Science, with images taken from Duffy et al.

The PLoS Medicine Debate

What Is the Best Approach to Reducing Birth Defects Associated with Isotretinoin?

Lorien Abroms, Edward Maibach, Katherine Lyon-Daniel, Steven R Feldman

Health in Action

Policy Forums

Putting It Together: AIDS and the Millennium Development Goals

Robert Hecht, Anita Alban, Kate Taylor, Sarah Post, Nina B Andersen, Ryan Schwarz

Criteria for Drugs Used in Pre-Exposure Prophylaxis Trials against HIV Infection

Inge Derdelinckx, Mark A Wainberg, Joep M. A Lange, Andrew Hill, Yasmin Halima, Charles A. B Boucher

Research in Translation

The Mechanistic Classification of Addictive Drugs

Christian Lüscher, Mark A Ungless

Research Articles

Packaging Health Services When Resources Are Limited: The Example of a Cervical Cancer Screening Visit

Jane J Kim, Joshua A Salomon, Milton C Weinstein, Sue J Goldie

Adherence to HAART: A Systematic Review of Developed and Developing Nation Patient-Reported Barriers and Facilitators

Edward J Mills, Jean B Nachega, David R Bangsberg, Sonal Singh, Beth Rachlis, Ping Wu, Kumanan Wilson, Iain Buchan, Christopher J Gill, Curtis Cooper

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Dominance of HIV-1 Subtype CRF01_AE in Sexually Acquired Cases Leads to a New Epidemic in Yunnan Province of China

Yong Zhang, Lin Lu, Lei Ba, Li Liu, Li Yang, Manhong Jia, Haibo Wang, Qing Fang, Yuhua Shi, Wenyun Yan, Guangcai Chang, Linqi Zhang, David D Ho, Zhiwei Chen

Complement Lysis Activity in Autologous Plasma Is Associated with Lower Viral Loads during the Acute Phase of HIV-1 Infection

Michael Huber, Marek Fischer, Benjamin Misselwitz, Amapola Manrique, Herbert Kuster, Barbara Niederöst, Rainer Weber, Viktor von Wyl, Huldrych F Günthard, Alexandra Trkola

Targeted Killing of Virally Infected Cells by Radiolabeled Antibodies to Viral Proteins

Ekaterina Dadachova, Mahesh C Patel, Sima Toussi, Christos Apostolidis, Alfred Morgenstern, Martin W Brechbiel, Miroslaw K Gorny, Susan Zolla-Pazner, Arturo Casadevall, Harris Goldstein

Internet Use among Ugandan Adolescents: Implications for HIV Intervention

Michele L Ybarra, Julius Kiwanuka, Nneka Emenyonu, David R Bangsberg

Related Articles

  1. Where the Most Private Becomes Public: Policy Making for Sexual Health

Population Pharmacokinetics of Artesunate and Dihydroartemisinin following Intra-Rectal Dosing of Artesunate in Malaria Patients

Julie A Simpson, Tsiri Agbenyega, Karen I Barnes, Gianni Di Perri, Peter Folb, Melba Gomes, Sanjeev Krishna, Srivicha Krudsood, Sornchai Looareesuwan, Sharif Mansor, Helen McIlleron, Raymond Miller, Malcolm Molyneux, James Mwenechanya, Visweswaran Navaratnam, Francois Nosten, Piero Olliaro, Lorrin Pang, Isabela Ribeiro, Madalitso Tembo, Michele van Vugt, Steve Ward, Kris Weerasuriya, Kyaw Win, Nicholas J White

OPC-67683, a Nitro-Dihydro-Imidazooxazole Derivative with Promising Action against Tuberculosis In Vitro and In Mice

Makoto Matsumoto, Hiroyuki Hashizume, Tatsuo Tomishige, Masanori Kawasaki, Hidetsugu Tsubouchi, Hirofumi Sasaki, Yoshihiko Shimokawa, Makoto Komatsu

Disease Biomarkers in Cerebrospinal Fluid of Patients with First-Onset Psychosis

Jeffrey T.-J Huang, F. Markus Leweke, David Oxley, Lan Wang, Nathan Harris, Dagmar Koethe, Christoph W Gerth, Brit M Nolden, Sonja Gross, Daniela Schreiber, Benjamin Reed, Sabine Bahn