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Role of Nesprin-2 and RanBP2 in BICD2-associated brain developmental disorders

March 17, 2023

Role of Nesprin-2 and RanBP2 in BICD2-associated brain developmental disorders

Image credit: Robina Weermeijer, Unsplash

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Current Issue February 2023

02/27/2023

Research Article

Allelic contribution of Neurexin 1α to autism-relevant behavioral phenotypes in mice

Findings from Xu, Ho & Fasolino et al support the importance of sex, genetic structure, and the amount of functional Neurexin 1 product in eliciting ASD-relevant behaviors, and the need for animal models carrying anomalies at multiple genes to elucidate the genetic underpinnings of autism.

Allelic contribution of Neurexin 1α to autism-relevant behavioral phenotypes in mice

Image credit: Ishan Manjrekar

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PLOS Genetics | ISSN: 1553-7404 (online)