Whole-genome analysis of Malawian Plasmodium falciparum isolates identifies possible targets of allele-specific immunity to clinical malaria
Shah et al. analyze genome-wide polymorphisms in 140 Plasmodium falciparum isolates from a longitudinal study in Malawi. They identify 25 genes that encode possible targets of naturally acquired immunity to malaria, which could have potential as vaccine candidates.
Image credit: Adrian V. S. Hill, 10.1098/rstb.2011.0091