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Genetic analysis of the modern Australian labradoodle dog breed reveals an excess of the poodle genome

September 10, 2020

Genetic analysis of the modern Australian labradoodle dog breed reveals an excess of the poodle genome

A new study by Muhammad Basil Ali and colleagues shows that, genetically, the Australian labradoodle designer dog breed - developed from a cross of poodles and Labrador retrievers - is primarily poodle.

Image credit: proconsult, Pixabay

Topic Pages

Read the full Collection of Topic Pages published in PLOS Genetics.

Collection

08/31/2020

Research Article

Sequential activation of Notch and Grainyhead gives apoptotic competence to Abdominal-B expressing larval neuroblasts in Drosophila Central nervous system

This study from Bakshi et al. highlights that Hox dependent neuroblast apoptosis in abdominal and terminal regions of Drosophila utilizes common molecular players (Hox, Grh and Notch), but seems to have evolved different molecular strategies to pattern the developing central nervous system.

Image credit: journal.pgen.1008976.g005

Sequential activation of Notch and Grainyhead gives apoptotic competence to Abdominal-B expressing larval neuroblasts in Drosophila Central nervous system

Recently Published Articles

Current Issue

Current Issue August 2020

09/04/2020

Research Article

Excess crossovers impede faithful meiotic chromosome segregation in C. elegans

In this study, Hollis and colleagues find that increasing crossover number during meiosis negatively impacts chromosome segregation by altering chromosome-associated structures, leading to misalignment of the chromosomes on the meiotic spindle. Their results highlight the importance of limiting crossover numbers to enable faithful chromosome segregation during sperm and egg development.

Image credit: journal.pgen.1009001.g003

Excess crossovers impede faithful meiotic chromosome segregation in C. elegans

08/31/2020

Research Article

Serotonergic modulation of visual neurons in Drosophila melanogaster

In this work, Sampson and colleagues have found serotonin receptors expressed in all neuropils of the Drosophila melanogaster optic lobe and identified specific neurons involved in visual information processing that express serotonin receptors. Their data support a role for the serotonergic neuromodulation of interneurons in the Drosophila visual system.

Image credit: journal.pgen.1009003.g001

Serotonergic modulation of visual neurons in Drosophila melanogaster

07/27/2020

Research Article

The evolution and functional divergence of the histone H2B family in plants

Jiang, Borg and colleagues report a systematic analysis of the histone H2B family in plants. The authors identify a new class of highly divergent H2B variants, H2B.S, that specifically accumulate during chromatin compaction of dry seed embryos in multiple species of flowering plants. 

The evolution and functional divergence of the histone H2B family in plants

Image credit: Jiang, Borg and colleagues

07/30/2020

Topic Page

Holocentric chromosomes

Mauro Mandrioli and Gian Carlo Manicardi discuss existing research on holocentric chromosomes, which possess multiple kinetochores along their length rather than the single centromere typical of other chromosomes. This article was also published as a live article on Wikipedia.

Holocentric chromosomes

Image credit: Mandrioli and Manicardi

07/15/2020

Editorial

Mixed methods

Editors in Chief Gregory Barsh and Gregory Copenhaver and newly appointed Section Editors David Balding and Chengqi Yi announce the new PLOS Genetics Methods section.

Mixed methods

Image credit: Rube Goldberg, Wikimedia Commons, CC0

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