September 16, 2024
Image credit: pgen.1011413
09/11/2024
research article
A SNP at MEF2C (rs6893807), linked to IQ, is observed to have a trans eQTL effect on BNIP3L, a prioritized risk gene from the largest SCZ genome-wide association study, involved in mitochondrial mitophagy.
Image credit: pgen.1011093
Current Issue September 2024
09/12/2024
research article
Ancestral sequence reconstruction and analyses of natural and chimeric variants identified six key amino acids involved in sensor-helper compatibility. These residues are positioned on multiple surfaces of the resting NRC3 homodimer, collectively contributing to their compatibility with Rpi-blb2.
Image credit: pgen.1011402
09/11/2024
research article
Using an evolutionary method that examines proteins that evolve at similar rates, the authors identified proteins within glycosylation pathways and among other unexpected pathways, such as ncRNA modification and DNA repair, that could be potential genetic modifiers of CDG genes.
Image credit: pgen.1011406
09/16/2024
research article
Using laboratory evolution as a strategy for improving the fitness of reduced-genome strains created for biotechnology applications.
Image credit: pgen.1011306
09/09/2024
research article
NF-κB transcription factor Relish (Rel) shields the progenitor pool from the metabolic pathway that inducts them into the differentiation program by curtailing the activation of JNK.
Image credit: pgen.1011403
09/10/2024
research article
In the absence of H2A.Z, RNA polymerases persist on damaged DNA, causing interference with DNA replication and genome instability.
Image credit: pgen.1011300
08/07/2024
research article
Reveals a non-coding sequence near the kpc-1 gene essential for neuronal circuit function in C. elegans ...
Image credit: pgen.1011362
08/05/2024
research article
Understanding post-DNA binding functions of Fkh1 to promote early origin activity.
Image credit: pgen.1011366
08/05/2024
research article
Linking CroR response regulator to endogenous cell envelope stress, showing that inactivating CroR partially restores piliation and cell morphology ...
Image credit: pgen.1011071
Five new journals unified in addressing global health and environmental challenges are now ready to receive submissions: PLOS Climate, PLOS Sustainability and Transformation, PLOS Water, PLOS Digital Health, and PLOS Global Public Health
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PLOS ONE is now accepting submissions of Lab Protocols, a peer-reviewed article collaboration with protocols.io, and Study Protocols, an article that credits the work done prior to producing and publishing results.
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PLOS Genetics welcomes several new Associate Editors to our board: Nicolas Bierne, Julie Simpson, Yun Li, Hongbin Ji, Hongbing Zhang, Bertrand Servin, & Benjamin Schwessinger
The former Natural Variation section at PLOS Genetics relaunches as Human Genetic Variation and Disease. Read the editors' reasoning behind this change.
Quanjiang Ji (ShanghaiTech University) joined the editorial board and Xiaofeng Zhu (Case Western Reserve University) was promoted as new Section Editors for the PLOS Genetics Methods section.
Congratulations to Associate Editor Michael Lichten and Consulting Editor Nicole King, who are newly elected members of the National Academy of Sciences.
Congratulations to Associate Editor Harmit Malik, who was awarded the Edward Novitski Prize by the Genetics Society of America for his work on genetic conflict. Harmit has also been elected as a new member of the American Academy of Arts & Sciences.
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