NCK-associated protein 1 like (nckap1l) minor splice variant regulates intrahepatic biliary network morphogenesis
Ghaffari et al. study intrahepatic biliary network formation, involved in cholestatic liver diseases and autoimmune disorders, in zebrafish. They find a mutation in the nckap1l gene that disrupts the actin organization of biliary epithelial cells.
Image credit: Ghaffari et al., pgen.1009402