Advertisement

PLOS Research News: stay up to date with research from across PLOS

PLOS Research News

10/12/2018

RESEARCH ARTICLE 

Antimicrobial peptides modulate long-term memory

Raquel Barajas-Azpeleta, Jianping Wu and colleagues report a novel and unanticipated example of how immune genes influence nervous system function. Exploring how Drosophila form long-lasting memories of certain experiences, they found that antimicrobial peptides that fight bacteria in the body are expressed in the head, and control whether an animal would form long-term memory of a food source or an unsuccessful mating experience. 

Image credit: Raquel Barajas-Azpeleta, Jianping Wu and colleagues

Antimicrobial peptides modulate long-term memory

Recently Published Articles

Current Issue

Current Issue September 2018

10/12/2018

RESEARCH ARTICLE

Genome amplification and cellular senescence are hallmarks of human placenta development

Genome amplification and cellular senescence are commonly associated with pathological processes. While physiological roles for polyploidization and senescence have been described in mouse development, controversy exists over their significance in humans. Here, Philipp Velicky and colleagues describe tetraploidization and senescence as phenomena of normal human placenta development. 

Image credit: Philipp Velicky and colleagues

Genome amplification and cellular senescence are hallmarks of human placenta development

10/18/2018

RESEARCH ARTICLE

Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein

The Fanconi Anemia (FA) pathway is important for repairing interstrand crosslinks (ICLs) between the two strands of the DNA double helix. An initial and essential stage in the repair process is the detection of the ICL.  Anna Motnenko and colleagues report the identification of UHRF2, a paralogue of UHRF1, as an ICL sensor protein. The authors show that UHRF2 cooperates with UHRF1, to ensure recruitment of FANCD2 to ICLs.

Image credit: Anna Motnenko and colleagues

Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein

10/08/2018

research article

LytTR Regulatory Systems: A potential new class of prokaryotic sensory system

Zhengzhong Zou and colleagues provide the first evidence for the existence of a potentially new class of prokaryotic sensory system - LytTR Regulatory Systems (LRS). The authors show that LRS are broadly distributed among prokaryotes and are distinct from the other commonly studied sensory systems such as two-component signal transduction systems and ECF sigma factor systems.

LytTR Regulatory Systems: A potential new class of prokaryotic sensory system

Image credit: Zhengzhong Zou and colleagues

09/13/2018

review

Structure and function of archaeal histones

Bram Henneman and colleagues discuss the many possibilities of archaeal histone involvement in transcription regulation.

Structure and function of archaeal histones

Image credit: Bram Henneman and coleagues

08/30/2018

review

PRDM9, a driver of the genetic map

Corinne Grey and colleagues discuss the current knowledge about the molecular features of PRDM9 as a DNA-binding protein and epigenetic modifier and how those features contribute to drive double strand break formation.

PRDM9, a driver of the genetic map

Image credit: Corine Grey and colleagues

Get new content from PLOS Genetics in your inbox

Thank you! You have successfully subscribed to the PLOS Genetics newsletter.

Sorry, an error occurred while sending your subscription. Please try again later.

Try again