A genome-wide Drosophila epithelial tumorigenesis screen identifies Tetraspanin 29Fb as an evolutionarily conserved suppressor of Ras-driven cancer

Here, Ning Xu and colleagues show that transcription factor OsMADS25 positively regulates the root system development and tolerance to salinity and oxidative stress in rice plants, and provide strong evidence that OsMADS25 increases ROS-scavenging capacity and proline accumulation.

Saba N. Baskoylu and colleagues report on the first single-copy, ALS knock-in models in C. elegans generated by transposon- or CRISPR/Cas9- mediated genome editing of the endogenous sod-1 gene.

Zhengzhong Zou and colleagues provide the first evidence for the existence of a potentially new class of prokaryotic sensory system - LytTR Regulatory Systems (LRS). The authors show that LRS are broadly distributed among prokaryotes and are distinct from the other commonly studied sensory systems such as two-component signal transduction systems and ECF sigma factor systems.