October 13, 2022
Image credit: Wu et al.
10/12/2022
Research Article
Galanti et al. show that natural epigenetic variation in Thlaspi arvense is significantly associated with both DNA sequence and environment of origin, and that the relative importance of the two factors strongly depends on the sequence context of DNA methylation.
Image credit: Dario Galanti
Current Issue October 2022
10/14/2022
Research Article
Schroeder et al. present a new class of genes involved in protein biogenesis that display tissue- and temporal-specific activities that are crucial for proper heart development.
Image credit: Schroeder et al.
10/03/2022
Research Article
García-Ferrés et al. use the snail gland specific enhancer as a proxy for gland formation, and show that the glands are specified by the same inputs specifying the trachea. These include the JAK/STAT, the Hedgehog and Wingless signaling pathways as well as inputs from the Hox genes.
Image credit: Mar García-Ferrés
10/03/2022
Research Article
Gang et al. study an ON/OFF switch in C. elegans that controls immune responses to diverse natural pathogens of the skin and gut. They show a physical association between the ‘ON switch’ protein PALS-25 and the ‘OFF switch’ protein PALS-22, and that this association is disrupted in a mutant, activated form of PALS-25.
Image credit: Gang et al.
10/05/2022
Research Article
Kim et al. show how DDX6 affects the development of the three primary germ layers during early mouse embryogenesis and the underlying mechanism of DDX6 function.
Image credit: Kim et al.
10/05/2022
Research Article
Simmons et al. show that there is an association between Drosophila gypsy insulator proteins and the phosphorylated version of the histone variant H2Av (γH2Av).
Image credit: Simmons et al.
10/27/2022
Review
Valet & Narbonne outline progress made in our understanding of in vivo stem cell regulation, concluding that 2 types of stem cell deregulations can provoke the formation of benign tumors.
Image credit: pgen.1010434
10/27/2022
Viewpoints
Davis examines the controversy behind the publication of R.A. Fisher’s 1918 paper, which has been celebrated as a major turning point for the field of human genetics.
Image credit: Cheska Poon, Pixabay
09/22/2022
Review
Steiner & Novembre review theoretical models for the spatial spread of adaptive variants and identify areas to be improved in future work.
Image credit: Elena Mozhvilo, Unsplash
09/15/2022
Review
Ononye & Downey summarize the type and functions of posttranslational modifications proposed to control Gcn5 in both yeast and human cells.
Image credit: pgen.1010352
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PLOS Genetics welcomes several new Associate Editors to our board: Karen Avraham, Anne O'Donnell Luria, Neil Hanchard, Aimee Shen, Jan-Willem Veening, Susana Campino, Nicolas Bierne, Julie Simpson, & Yun Li
The former Natural Variation section at PLOS Genetics relaunches as Human Genetic Variation and Disease. Read the editors' reasoning behind this change.
Quanjiang Ji (ShanghaiTech University) joined the editorial board and Xiaofeng Zhu (Case Western Reserve University) was promoted as new Section Editors for the PLOS Genetics Methods section.
Congratulations to Associate Editor Michael Lichten and Consulting Editor Nicole King, who are newly elected members of the National Academy of Sciences.
Congratulations to Associate Editor Harmit Malik, who was awarded the Edward Novitski Prize by the Genetics Society of America for his work on genetic conflict. Harmit has also been elected as a new member of the American Academy of Arts & Sciences.
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