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February 21, 2025

PLOS statement on recent US Executive Orders

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Current Issue April 2025

06/09/2025

research article

Environmental data provide marginal benefit for predicting climate adaptation

In this study, the authors use genotype data to predict environmental characteristics of maize germplasm collections and identify varieties potentially pre-adapted to target environments. They find that environment-of-origin data and genome scans for climate-associated loci offer little benefit for prioritizing accessions, despite evidence of environmental adaptation.

Image credit: pgen.1011714

Environmental data provide marginal benefit for predicting climate adaptation

06/17/2025

research article

The PavMYB.C2-UFGT module contributes to fruit coloration via modulating anthocyanin biosynthesis in sweet cherry

In this study, the authors conduct a metabolomic analysis revealing that both total anthocyanin content and the relative abundance of individual anthocyanin species contribute to fruit color variation observed between yellow- and dark red-fruited cultivars, and identify PavMYB.C2 as a key regulator controlling anthocyanin biosynthesis and Cy3G accumulation.

Image credit: pgen.1011761

The PavMYB.C2-UFGT module contributes to fruit coloration via modulating anthocyanin biosynthesis in sweet cherry

06/10/2025

research article

A mathematical framework for the quantitative analysis of genetic buffering

In this report, the author describes a novel mathematical framework for quantifying genetic buffering relationships between genes, introducing a new neutrality model that enables gene interactions to be formally defined, compared and classified across systems in a consistent and generalizable way.

A mathematical framework for the quantitative analysis of genetic buffering

Image credit: pgen.1011730

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PLOS Genetics | ISSN: 1553-7404 (online)