March 17, 2023
Image credit: Robina Weermeijer, Unsplash
03/14/2023
Research Article
The sleep neuron RIS in Caenorhabditis elegans is required to induce sleep behavior and to promote survival upon stress. Busack and Bringmann show that RIS can provide survival benefits even when sleep behavior is disturbed.
Image credit: pgen.1010665
Current Issue February 2023
03/06/2023
Research Article
The ability of ADAR enzymes to recode at the mRNA level makes them attractive therapeutic tools. Avram-Shperling et al develop a novel approach to identify highly potent natural ADARs that could be used to induce high-level RNA editing.
Image credit: pgen.1010661
03/16/2023
Research Article
Wünnemann et al use CRISPR to test if genes near genetic variants implicated by a genome-wide association study in heart attacks modulate the functions of vascular endothelial cells.
Image credit: pgen.1010680
03/17/2023
Research Article
To date, the histone chaperone that stabilizes H3-H4 in the early Drosophila embryo has remained unknown. Based on sequence, structure and function, Tirgar et al show that the Drosophila homolog of NASP is the critical H3-H4 histone chaperone in the Drosophila early embryo.
Image credit: pgen.1010682
02/27/2023
Research Article
Findings from Xu, Ho & Fasolino et al support the importance of sex, genetic structure, and the amount of functional Neurexin 1 product in eliciting ASD-relevant behaviors, and the need for animal models carrying anomalies at multiple genes to elucidate the genetic underpinnings of autism.
Image credit: Ishan Manjrekar
02/27/2023
Research Article
In the largest canine cohort examined in a single study to date, Donner, Freyer & Davison et al screen 250 genetic variants to shed light on their prevalence and breed distribution. This work provides an important resource to guide genetic counseling for inherited diseases across the dog population.
Image credit: pgen.1010651
02/27/2023
Research Article
Currant and colleagues
Image credit: pgen.1010587
02/23/2023
Research Article
Cheng, Zhang, Wen and colleagues
Image credit: pgen.1010615
02/27/2023
Research Article
Gorlov & Amos
Image credit: NIH
03/01/2023
Research Article
Tran and colleagues
Image credit: pgen.1010636
Five new journals unified in addressing global health and environmental challenges are now ready to receive submissions: PLOS Climate, PLOS Sustainability and Transformation, PLOS Water, PLOS Digital Health, and PLOS Global Public Health
The COVID-19 Collection highlights all content published across the PLOS journals relating to the COVID-19 pandemic.
PLOS ONE is now accepting submissions of Lab Protocols, a peer-reviewed article collaboration with protocols.io, and Study Protocols, an article that credits the work done prior to producing and publishing results.
A collection of free training and resources for peer reviewers of PLOS journals—and for the peer review community more broadly—drawn from research and interviews with staff editors, editorial board members, and experienced reviewers.
PLOS Computational Biology's "Ten Simple Rules" articles provide quick, concentrated guides for mastering some of the professional challenges research scientists face in their careers.
PLOS Genetics welcomes several new Associate Editors to our board: Nicolas Bierne, Julie Simpson, Yun Li, Hongbin Ji, Hongbing Zhang, Bertrand Servin, & Benjamin Schwessinger
The former Natural Variation section at PLOS Genetics relaunches as Human Genetic Variation and Disease. Read the editors' reasoning behind this change.
Quanjiang Ji (ShanghaiTech University) joined the editorial board and Xiaofeng Zhu (Case Western Reserve University) was promoted as new Section Editors for the PLOS Genetics Methods section.
Congratulations to Associate Editor Michael Lichten and Consulting Editor Nicole King, who are newly elected members of the National Academy of Sciences.
Congratulations to Associate Editor Harmit Malik, who was awarded the Edward Novitski Prize by the Genetics Society of America for his work on genetic conflict. Harmit has also been elected as a new member of the American Academy of Arts & Sciences.
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