From wrist to research: Harnessing smartwatch data for equitable cardiovascular research

Manpreet Kaur, on behalf of the PLOS Medicine Staff Editors

PLOS Medicine: published September 28, 2026 | https://doi.org/10.1371/journal.pmed.1005260

The widening medication adherence gap

Zachary A. Marcum

PLOS Medicine: published September 4, 2026 | https://doi.org/10.1371/journal.pmed.1005237

Collective interests, health research ethics and data governance for Indigenous Sámi populations

Susanna Ragnhild Andersdatter Siri, Christina Storm Mienna, Per Axelsson

PLOS Medicine: published September 14, 2026 | https://doi.org/10.1371/journal.pmed.1005250

Living with a rare disease: Why lived experience must shape research

Gemma Whyatt, Jodi Whitehouse

PLOS Medicine: published September 18, 2026 | https://doi.org/10.1371/journal.pmed.1005253

HIV self-testing and the global diagnostic gap: Addressing a decade of missed opportunity

Reuben Granich, Somya Gupta, Isabelle Munyangaju, Mike Ruffner

PLOS Medicine: published September 16, 2026 | https://doi.org/10.1371/journal.pmed.1005241

The inverted pyramid of care in modern-day obstetrics

Laura A. Magee, Peter von Dadelszen, Kypros H. Nicolaides

PLOS Medicine: published September 28, 2026 | https://doi.org/10.1371/journal.pmed.1005255

Evaluation of the FI-Lab, a laboratory-based, automated frailty index for acute care: A multicohort study

Hugh Logan Ellis, Peter Hanlon, Liam Dunnell, Martin Whyte, Daniel H. J. Davis, Josephine Bates, Adeel Jafri, Diana Shamsutdinova, James T. Teo, Zina Ibrahim, Kenneth Rockwood

PLOS Medicine: published September 1, 2026 | https://doi.org/10.1371/journal.pmed.1005004

Human papillomavirus infection and risk of cardiovascular disease: A population-based matched cohort study with sibling analysis

Yunyang Deng, Mark Clements, Chaonan Shen, Jonas F. Ludvigsson, Qing Shen, Jiayao Lei

PLOS Medicine: published September 1, 2026 | https://doi.org/10.1371/journal.pmed.1005222

Effect of a person-centered care intervention on return and sustained reengagement after treatment interruptions from HIV care in Zambia: A post-hoc analysis of a stepped-wedged cluster randomized trial

Aaloke Mody, Kombatende Sikombe, Sandra Simbeza, Njekwa Mukamba, Laura K. Beres, Jake M. Pry, Anjali Sharma, Jacob Mutale, Alida Zulu Dube, Musunge Mulabe, Lloyd Mulenga, Suilanji Sivile, April Ratliff, Charles W. Goss, Charles B. Holmes, Carolyn Bolton Moore, Izukanji Sikazwe, Elvin H. Geng

PLOS Medicine: published September 1, 2026 | https://doi.org/10.1371/journal.pmed.1005052

Maternal body mass index in early pregnancy and offspring mortality up to early adulthood: A nationwide cohort study

Hui Wang, Hua Chen, Jette Möller, Yajun Liang, Krisztina D. László

PLOS Medicine: published September 1, 2026 | https://doi.org/10.1371/journal.pmed.1005217

Neutralising antibodies and protection from progression to severe COVID-19: A meta-analysis

Karen M. Elias, Ainslie Mitchell, Eva Stadler, Timothy E. Schlub, Shanchita R. Khan, Claire Xue, Stephen J. Kent, Deborah Cromer, Miles P. Davenport, David S. Khoury

PLOS Medicine: published September 2, 2026 | https://doi.org/10.1371/journal.pmed.1005230

Association between nirsevimab coverage and pediatric emergency department visits for bronchiolitis in 12 European countries: An interrupted time-series analysis

Léa Lenglart, Luigi Titomanlio, Ilaria Alberti, Laura Almeida, Camille Aupiais, Esra Akyüz Özkan, Michael Barrett, Romain Basmaci, Ahmet Birbilen, Dorine Borensztajn, Catarina Braz Schönenberger, Silvia Bressan, Danilo Buonsenso, Teresa Campos, Susana Castanhinha, Antonio Chiaretti, Gemma Claret, Francesca De Zan, Sheena Durnin, Laszlo Fodor, Borja Gomez, Susanne Greber-Platzer, Romain Guedj, Alexander Huege, Fiona Leonard, Ian K. Maconochie, Robin Marlow, Gregorio Milani, Miguel Angel Molina Gutierrez, Anna Maria Musolino, Rianne Oostenbrink, Zanda Pucuka, Simon Rivière, Damian Roland, Malin Ryd Rinder, Maria Chiara Supino, Ozlem Teksam, Victoria Trenchs, Zaba Valtuille, Bento Vanda, Sanne Vrijlandt, Naim Ouldali, Ruud G. Nijman, the EPISODES Study Group

PLOS Medicine: published September 3, 2026 | https://doi.org/10.1371/journal.pmed.1005223

Overall and serotype-specific dengue virus transmission intensity in Mexico, 2016–2023: A modelling study of case-notification data

Oliver S. Simmons, Anna Vicco, Ruth A. Martínez-Vega, José Ramos-Castañeda, Ilaria Dorigatti

PLOS Medicine: published September 3, 2026 | https://doi.org/10.1371/journal.pmed.1004874

Effect of a digitally augmented general health promotion intervention on abstinence from health-risk behaviors among emergency department discharge patients: A randomized controlled trial

Ho Cheung William Li, Wei Xia, Joanna Yeung, Laurie Long Kwan Ho, Tan Ankie Cheung, Kai Yeung Cheung, Yiu Cheung Chan, Wai Yee Chan, Chin Wai Lui, Hong Chen

PLOS Medicine: published September 8, 2026 | https://doi.org/10.1371/journal.pmed.1004916

Multimodal protective and susceptibility clusters in paediatric atopic dermatitis: A machine learning-based, data-driven observational study

Damir Zhakparov, Nonhlanhla Lunjani, Marco Schmid, Kathleen Moriarty, Damian Roquero, Anita Dreher, Jeannette I. Heldstab-Kast, Kari C. Nadeau, Cezmi Akdis, Michael Levin, Carol Hlela, Milena Sokolowska, Liam O’Mahony, Katja Baerenfaller

PLOS Medicine: published September 8, 2026 | https://doi.org/10.1371/journal.pmed.1004917

Country- and individual-level factors associated with healthy working life expectancy: A multinational longitudinal study

Jingjie Zhu, Bo Ye, Zeyu Huang, Huazhen You, Junjia Jiang, Shitong Yang, Junling Gao

PLOS Medicine: published September 10, 2026 | https://doi.org/10.1371/journal.pmed.1004676

HIV diagnosis and treatment status in individuals dying from HIV in Zimbabwe, Malawi, and South Africa: A model comparison analysis

Loveleen Bansi-Matharu, Daniel T. Citron, Rowan Martin-Hughes, Haroon Moolla, John Stover, Michael Pickles, Tara Mangal, Jenny Smith, Owen Mugurungi, Mmatlou Simeon Kubyana, Isaac Taramusi, Valentina Cambiano, Amon Mpofu, Debra ten Brink, Edinah Mudimu, Tsitsi Apollo, Anna Bershteyn, Linley Chewere, Dobromir Dimitrov, Stephen Macheso, Leigh F. Johnson, Andrew Phillips

PLOS Medicine: published September 10, 2026 | https://doi.org/10.1371/journal.pmed.1004864

The longitudinal care cascade for hypertension in people with and without HIV in South Africa: A clinic-based observational study

Siphamandla Bonga Gumede, Jennifer Manne-Goehler, Elizabeth Kelechi Oladimeji, Nicola Bulled, Alana T. Brennan, Samanta Tresha Lalla-Edward

PLOS Medicine: published September 11, 2026 | https://doi.org/10.1371/journal.pmed.1004957

Protein mediators of chronic kidney disease in Type 2 diabetes: A mendelian randomization study

Kevin Y. H. Liang, Thomas M. Zheng, Dandan Tan, Takayoshi Sasako, Yann Ilboudo, Yiheng Chen, Guillaume Butler-Laporte, Satoshi Yoshiji, J. Brent Richards

PLOS Medicine: published September 11, 2026 | https://doi.org/10.1371/journal.pmed.1004802

Predicting resistance to fluoroquinolones among patients with rifampicin-resistant tuberculosis: A cross-country validation study

Tianfang Shao, Mariana R. Neves, Molly Franke, Carole Mitnick, Jennifer Furin, Ted Cohen, Reza Yaesoubi

PLOS Medicine: published September 15, 2026 | https://doi.org/10.1371/journal.pmed.1004965

The retail food environment following a mandatory healthy checkout policy: A natural experimental evaluation

Yuru Huang, Ethan C. Wolf, Andrea M. Gil, Kris Jayme G. Matas, Lisa M. Powell, Rebecca M. Schermbeck, Jennifer Falbe

PLOS Medicine: published September 16, 2026 | https://doi.org/10.1371/journal.pmed.1004814

Accelerometer-derived real-world sleep stages and risk of incident diseases: A UK Biobank cohort study and phenome-wide association analysis

Jingsong Luo, Ruiyi Liu, Jie Yin, Wangnan Cao, Shengzhi Sun, Rui Chen

PLOS Medicine: published September 17, 2026 | https://doi.org/10.1371/journal.pmed.1005213

Blood test trend versus single threshold abnormality to discriminate cancer from non-cancer in patients with unexpected weight loss: A retrospective cohort study

Brian D. Nicholson, Clare R. Bankhead, Sufen Zhu, Jason Lee Oke, Cynthia Wright Drakesmith, Rafael Perera, Frederick D. Richard Hobbs, Pradeep S. Virdee

PLOS Medicine: published September 17, 2026 | https://doi.org/10.1371/journal.pmed.1004956

Association of a multiple risk factor assessment and intervention program with risk of diabetes: A population-based matched cohort study

Ernst Bergman, Anna Nordström, Lars Nyberg, Peter Nordström

PLOS Medicine: published September 21, 2026 | https://doi.org/10.1371/journal.pmed.1005043

Global, regional, and national impact of epidemic disasters on health workforce equality between 1990 and 2019: An ecological and modeling study

Manman Chen, Wanzhou Wang, Feng Sha, Zichen Ye, Yuankai Zhao, Chao Yang, Ze Liang, Yu Jiang, Xijie Wang, Jinling Tang

PLOS Medicine: published September 22, 2026 | https://doi.org/10.1371/journal.pmed.1005134

Evaluation of the tuberculosis notification impact from an intermediary-facilitated public–private mix intervention in Viet Nam: A population-level quasi-experimental study

Luan Nguyen Quang Vo, Thuy Thi Thu Dong, Huy Ba Huynh, Binh Anh Luong, Huong Thi Lan Mo, Andrew James Codlin, Rachel Forse, Thuy Doan To Mai, Lan Phuong Nguyen, Jacob Creswell, Luong Van Dinh, Hoa Binh Nguyen, Phu Xuan Vu, Tuan Dinh Nguyen, Lan Huu Nguyen, Thi Minh Ha Dang, Son Van Luu, Nam Hoang Do, Huyen Thanh Truong, Phan Do Nguyen, Tushar Garg, Jad Shedrawy, Kristi Sidney Annerstedt, Minh Huy Pham, Jamie Tonsing, Tom Wingfield, Mohammed Ahmed Yassin, Nhung Viet Nguyen, Knut Lönnroth

PLOS Medicine: published September 23, 2026 | https://doi.org/10.1371/journal.pmed.1005144

The effect of lifestyle interventions in women with polyendocrine metabolic ovarian syndrome: A systematic review and meta-analysis

Oladipupo Olalere, Min-Dee Koh, Katie Crabb, Olanike Ajijola, Saba Tariq, Chau Thien Tay, Aya Mousa, Soha Sobhy, Lynne Robinson, Rima Dhillon-Smith, Kathy Hoeger, Lisa Moran, Helena Teede, Shakila Thangaratinam

PLOS Medicine: published September 23, 2026 | https://doi.org/10.1371/journal.pmed.1004887

Encampment sweeps and persistent homelessness among unhoused people who use drugs in Vancouver, Canada: A prospective cohort study

Kanna Hayashi, Eric C. Sayre, Jennifer McDermid, Samona Marsh, Caitlin Shane, Michael-John Sheridan Milloy, P.O.W.E.R., Thomas Kerr

PLOS Medicine: published September 24, 2026 | https://doi.org/10.1371/journal.pmed.1005033

Prenatal exposure to maternal depression and antidepressants and neurodevelopmental outcomes: A population cohort study

Saraid McIlvride, Neha Rao, Sarjit Singh, Scott M. Nelson, Jill P. Pell, Michael Fleming

PLOS Medicine: published September 29, 2026 | https://doi.org/10.1371/journal.pmed.1004658

Selective serotonin reuptake inhibitors and immune checkpoint blockade in solid tumors: A target trial emulation with pan-cancer transcriptomic analyses

Po-Huang Chen, Ming-Shen Dai, Mao-Hsuan Huang, Hsin-Yu Chen, Li-Ting Kao, Tina Yi-Jin Hsieh, Hong-Jie Jhou, Cho-Hao Lee

PLOS Medicine: published September 29, 2026 | https://doi.org/10.1371/journal.pmed.1005262

Assessing a multicomponent quality improvement strategy for chronic care of cardiovascular diseases in India: The C-QIP randomized feasibility trial

Kavita Singh, Ambuj Roy, Dimple Kondal, Kalyani Nikhare, Mareesha Gandral, Satish G. Patil, Kiran Aithal, Meenahalli Palleda Girish, Mohit Gupta, Kushal Madan, Jitendra P. S. Sawhney, Kamar Ali, Meetushi Jain, Savitesh Kushwaha, Devraj Jindal, Emily Mendenhall, Shivani A. Patel, Kabayam M. Venkat Narayan, Nikhil Tandon, Mark D. Huffman, Dorairaj Prabhakaran

PLOS Medicine: published September 29, 2026 | https://doi.org/10.1371/journal.pmed.1004932

The association between disability and mortality among children and adolescents: A systematic review and meta-analysis

Maureen Moyo-Chilufya, Arthemon Nguweneza, Sara Rotenberg, Hannah Kuper, Tracey Smythe

PLOS Medicine: published September 30, 2026 | https://doi.org/10.1371/journal.pmed.1004947

Correction: Evaluation of splenic accumulation and colocalization of immature reticulocytes and Plasmodium vivax in asymptomatic malaria: A prospective human splenectomy study

Steven Kho, Labibah Qotrunnada, Leo Leonardo, Benediktus Andries, Putu A. I. Wardani, Aurelie Fricot, Benoit Henry, David Hardy, Nur I. Margyaningsih, Dwi Apriyanti, Agatha M. Puspitasari, Pak Prayoga, Leily Trianty, Enny Kenangalem, Fabrice Chretien, Valentine Brousse, Innocent Safeukui, Hernando A. del Portillo, Carmen Fernandez-Becerra, Elamaran Meibalan, Matthias Marti, Ric N. Price, Tonia Woodberry, Papa A. Ndour, Bruce M. Russell, Tsin W. Yeo, Gabriela Minigo, Rintis Noviyanti, Jeanne R. Poespoprodjo, Nurjati C. Siregar, Pierre A. Buffet, Nicholas M. Anstey

PLOS Medicine: published September 22, 2026 | https://doi.org/10.1371/journal.pmed.1005254

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1. Evaluation of splenic accumulation and colocalization of immature reticulocytes and Plasmodium vivax in asymptomatic malaria: A prospective human splenectomy study