Table of Contents

September 2010

This month PLoS Medicine publishes a Debate that offers three unique perspectives on this question: Sofia Gruskin and Zyde Raad from the Harvard School of Public Health say more assessment is needed of such responsibilities; Geralyn Ritter, Vice President of Global Public Policy and Corporate Responsibility at Merck & Co. argues that multiple stakeholders could do more to help States deliver the right to health; and Paul Hunt and Rajat Khosla introduce Mr. Hunt's work as the UN Special Rapporteur on the right to the highest attainable standard of health (2002-2008), regarding the human rights responsibilities of pharmaceutical companies and access to medicines. In their accompanying Editorial, the PLoS Medicine Editors argue that drug companies should be held much more accountable for their human rights responsibilities.

Image Credit: cosmo flash (at

Health in Action

AIDS Vaccine for Asia Network (AVAN): Expanding the Regional Role in Developing HIV Vaccines

Stephen J. Kent, David A. Cooper, Mean Chhi Vun, Yiming Shao, Linqi Zhang, Nirmal Ganguly, Budiman Bela, Hiko Tamashiro, Rossana Ditangco, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Nguyen Van Kinh, Alan Bernstein, Saladin Osmanov, for the AIDS Vaccine for Asia Network investigators and supporters

Policy Forums

Examining the “Urban Advantage” in Maternal Health Care in Developing Countries

Zoë Matthews, Amos Channon, Sarah Neal, David Osrin, Nyovani Madise, William Stones

Does It Matter Who Writes Medical News Stories?

Amanda Wilson, Jane Robertson, Patrick McElduff, Alison Jones, David Henry

Seventy-Five Trials and Eleven Systematic Reviews a Day: How Will We Ever Keep Up?

Hilda Bastian, Paul Glasziou, Iain Chalmers

Research Articles

Cost-Effectiveness of Pooled Nucleic Acid Amplification Testing for Acute HIV Infection after Third-Generation HIV Antibody Screening and Rapid Testing in the United States: A Comparison of Three Public Health Settings

Angela B. Hutchinson, Pragna Patel, Stephanie L. Sansom, Paul G. Farnham, Timothy J. Sullivan, Berry Bennett, Peter R. Kerndt, Robert K. Bolan, James D. Heffelfinger, Vimalanand S. Prabhu, Bernard M. Branson

Community Case Management of Fever Due to Malaria and Pneumonia in Children Under Five in Zambia: A Cluster Randomized Controlled Trial

Kojo Yeboah-Antwi, Portipher Pilingana, William B. Macleod, Katherine Semrau, Kazungu Siazeele, Penelope Kalesha, Busiku Hamainza, Phil Seidenberg, Arthur Mazimba, Lora Sabin, Karen Kamholz, Donald M. Thea, Davidson H. Hamer

Combined Impact of Lifestyle-Related Factors on Total and Cause-Specific Mortality among Chinese Women: Prospective Cohort Study

Sarah J. Nechuta, Xiao-Ou Shu, Hong-Lan Li, Gong Yang, Yong-Bing Xiang, Hui Cai, Wong-Ho Chow, Butian Ji, Xianglan Zhang, Wanqing Wen, Yu-Tang Gao, Wei Zheng

Effectiveness of Chest Physiotherapy in Infants Hospitalized with Acute Bronchiolitis: A Multicenter, Randomized, Controlled Trial

Vincent Gajdos, Sandrine Katsahian, Nicole Beydon, Véronique Abadie, Loïc de Pontual, Sophie Larrar, Ralph Epaud, Bertrand Chevallier, Sylvain Bailleux, Alix Mollet-Boudjemline, Jean Bouyer, Sylvie Chevret, Philippe Labrune

Persistence with Statins and Onset of Rheumatoid Arthritis: A Population-Based Cohort Study

Gabriel Chodick, Howard Amital, Yoav Shalem, Ehud Kokia, Anthony D. Heymann, Avi Porath, Varda Shalev

A Genetic Association Study of Serum Acute-Phase C-Reactive Protein Levels in Rheumatoid Arthritis: Implications for Clinical Interpretation

Benjamin Rhodes, Marilyn E. Merriman, Andrew Harrison, Michael J. Nissen, Malcolm Smith, Lisa Stamp, Sophia Steer, Tony R. Merriman, Timothy J. Vyse