September 7, 2021
Image credit: Wieder et al
09/29/2021
Research Article
A major question in ecology is how to manage human intervention so as to achieve its goal without impairing ecosystem function. The main idea pursued here is the need to identify the inherent response ways of ecosystems to disturbances, and use them as road maps for conducting interventions.
Image credit: Zelnik et al.
Current Issue September 2021
10/05/2021
Research Article
Here the authors developed DeepCellState, a deep learning framework, with the goal of predicting the response in a given cell type based on the response in another cell type.
Image credit: Umarov et al.
09/27/2021
Research Article
Understanding relationships between spontaneous cancer in companion (pet) canines and humans can facilitate therapeutic development in both species. Towards this end the authors developed a protocol that analyzes canine transcriptomics data in the context of existing human data to evaluate comparative relevance of canine to human cancer.
Image credit: Tawa et al.
Image credit: Goscé et al
Image credit: Jabre et al.
Image credit: PLOS
11/18/2019
Featured Collection
"Ten Simple Rules" provide a quick, concentrated guide for mastering some of the professional challenges research scientists face in their careers.
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08/02/2021
FEATURED COLLECTION
The reproducibility of the research is a crucial element to keep science moving forward. I
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03/30/2021
FEATURED BLOG POST
PLOS Computational Biology has adopted an enhanced code sharing policy for all papers submitted from 30 March 2021.
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08/03/2020
FEATURED ISSUE IMAGE
Belcher et al estimated which clinically measurable properties of the tumor may help translate HBOC facilitated tumor oxygenation from murine models to the clinic.
Image credit: Belcher et al. pcbi.1008157
This Collection aims to increase the coverage of computational biology-related topics in Wikipedia by rewarding authors with a citable, PubMed-indexed static version of the living document on Wikipedia.
This series of perspective articles from computational biologists in a variety of countries, offers their personal viewpoint on the history, current status, and future of computational biology in their region.
This collection aims to provide practical tutorials and background information on important computational methods used to investigate key biological questions, as well as resources for training scientists at all stages of their careers.
The Benchmarking collection help readers decide between a number of methods which are developed to solve scientific problems.
Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform
Test accuracy of polymerase chain reaction methods against conventional diagnostic techniques for Cutaneous Leishmaniasis (CL) in patients with clinical or epidemiological suspicion of CL: Systematic review and meta-analysis
Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys
Prevalence and genetic profiles of isoniazid resistance in tuberculosis patients: A multicountry analysis of cross-sectional data
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