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10/03/2022

Research Article

Spatial models of pattern formation during phagocytosis

To study early events in phagocytosis, Herron et al used “frustrated phagocytosis”, an experimental system in which antibodies are micropatterned in disks on a cover slip. The cytoskeleton of cells attempting to phagocytose these disks organizes into “rosette” patterns around the disks, and they show that this pattern formation can occur through two general mechanisms.

Image credit: Herron et al, pcbi.1010092

Spatial models of pattern formation during phagocytosis

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PLOS Computational Biology | ISSN: 1553-7358 (online)