02/11/2019
RESEARCH ARTICLE
The proper positioning of division planes is key for correct development and morphogenesis of organs, in particular in plants were cellular walls prevent cell rearrangements. Elucidating how division planes are selected is therefore essential to decipher the cellular bases of plant morphogenesis.
Image credit: Trubuil, Palauqui, Andrey et al
Current Issue January 2019
02/13/2019
RESEARCH ARTICLE
n this paper, we report a reliability analysis for the estimation of “model basedness”—a psychological construct that informs a wealth of studies in animal, human and clinical research.
Image credit: Shahar et al
02/11/2019
RESEARCH ARTICLE
Electrocorticography (ECoG) is a type of electrophysiological monitoring that uses electrodes placed directly on the exposed surface of the brain. ECoG is a promising technique for studying the brain, and EcoG signals can be used to control brain-computer interfaces. Advances have made it possible to record simultaneously with an increasing number of smaller, and more closely spaced electrodes.
Image credit: Rogers, Gilja et al
02/11/2019
RESEARCH ARTICLE
In precision/personalized medicine of many conditions it is essential to investigate individual’s genome. Interpretation of the observed variation (mutation) sets is feasible only with computational approaches. We assessed the performance of variant pathogenicity/tolerance prediction programs on benign variants
Image credit: Vihinen et al
02/13/2019
RESEARCH ARTICLE
Cellular function and behaviour are driven by highly coordinated biomolecular interaction networks. A prime example is the protein-protein interaction network, often simply referred to as the “interactome”.
Image credit: Xia et al
02/14/2019
RESEARCH ARTICLE
Next-Generation Sequencing has made available substantial amounts of large-scale Omics data, providing unprecedented opportunities to understand complex biological systems. Specifically, the value of RNA-Sequencing (RNA-Seq) data has been confirmed in inferring how gene regulatory systems will respond under various conditions (bulk data) or cell types (single-cell data).
Image credit: Ma et al
02/11/2019
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Want to know what has been going on in the #BioJava library? 🤔 Read all about it in the latest publication - "BioJava 5: A community driven open-source bioinformatics library" https://plos.io/2tkZT7i @obf_news @PLOSCompBiol #PLOSCompBio #bioinformatics #opensource
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06/24/2005
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The image shows predicted functional linkage gene networks for large and small cytoplasmic ribosomal subunits in eukaryotes, derived from phylogenetic analysis of whole genomes.
Image credit: Barker et al.
08/13/2018
Featured Blog POST
Check out our Editors-in-Chief’s selection of papers from the July issue of PLOS Computational Biology.
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01/16/2019
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A global forum for research responding to the impacts of climate change
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Research in computational biology has given rise to a vast number of methods developed to solve scientific problems.
A global forum for open source hardware and software research and applications
Increasing numbers of women are entering science, technology, engineering, and mathematics (STEM) disciplines at undergraduate and graduate levels.
In the spirit of Open Con and highlighting the state of Open Data, PLOS is proud to release our Open Data Collection.
The switch between acute and persistent paramyxovirus infection caused by single amino acid substitutions in the RNA polymerase P subunit
A proposal for the future of scientific publishing in the life sciences
Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis
Potential public health benefits from cat eradications on islands
Marine environmental DNA biomonitoring reveals seasonal patterns in biodiversity and identifies ecosystem responses to anomalous climatic events
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