Self-organization of conducting pathways explains electrical wave propagation in cardiac tissues with high fraction of non-conducting cells

Valdano et al. study the ecological interaction between monopartite and multipartite forms, in terms of their ability to spread on, and take over, a host population. They reveal that this interaction can take various forms (competition, cooperation, commensality), depending on the underlying structure of contacts among hosts.

Individual neurons are primarily fast devices, yet neurons are also subject to additional biophysical processes, such as adaptive currents or synaptic filtering, that introduce slower dynamics in their activity. Beiran & Ostojic explore the possibility that slow network dynamics arise from such slow biophysical processes.

Biological pathways reveal the interactions among genes, providing a complementary way of understanding the drug response variation among individuals. Wang et al. aim to identify pathways that mediate the chemical response of each drug. They show that using the prior knowledge encoded in molecular networks substantially improves pathway identification.