12/06/2023
Research Article
Major depressive disorder is the most common psychiatric disorder and has a complex and heterogeneous etiology. Most treatments take weeks to show effects and work well only for a fraction of the patients. Thus, new concepts are needed to understand MDD and its dynamics.
Image credit: Damir Samatkulov
Current Issue November 2023
12/04/2023
Research Article
This study leveraged the capacity of artificial intelligence to model information processing in the human brain, to evaluate how the beauty of human faces and artistic paintings can be predicted from the efficiency of the neural code.
Image credit: Alina Grubnyak
12/08/2023
Research Article
It remains unknown how constraints on working memory resources affect instrumental learning under Pavlovian influence. The authors conducted a fMRI study in which participants completed an instrumental learning task with Pavlovian–instrumental conflict both with and without extra working memory load.
Image credit: Getty Images
12/07/2023
Perspective
As various workflows are proposed to facilitate Open Science, there is a need for collective action across funders, institutions, and governments to align on open science policies and practices to reduce the cost and friction of adoption
Image credit: Finn Hackshaw
12/04/2023
Research Article
Understanding the effect of different amino acid types on peptide assembly and nanofiber properties will allow the design of biomaterials with predetermined structural properties.
Image credit: Umberto
12/06/2023
Research Article
The novel dengue inhibitor JNJ-1802 can significantly reduce viral load in mice and non-human primates. This study used the mechanistic viral kinetic model calibrated against viral RNA data from experimental in-vitro infection studies to assess the in-vitro inhibitory effect of JNJ-1802.
Image credit: Yogesh Pedamkar
11/27/2023
Software
This study presents Provenance Replay, a tool for generating new executable code from results generated with the QIIME 2 bioinformatics platform.
Image credit: Markus Spiske
10/06/2023
Research Article
This study presents a differential equation-based mechano-chemical computational model, to investigate how substrate stiffness influences adhesion formation, maturation and disassembly.
Image credit: Shankar et al
10/16/2023
Research Article
This study describes a comprehensive workflow to simulate a variety of different types of heterogeneity and evaluate the performances of different integration methods.
Image credit: NCI
10/17/2023
Research Article
This paper presents Integrated Information Theory (IIT) 4.0. IIT aims to account for the properties of experience in physical (operational) terms.
Image credit: Albantakis et al
This Collection aims to increase the coverage of computational biology-related topics in Wikipedia by rewarding authors with a citable, PubMed-indexed static version of the living document on Wikipedia.
This series of perspective articles from computational biologists in a variety of countries, offers their personal viewpoint on the history, current status, and future of computational biology in their region.
This collection aims to provide practical tutorials and background information on important computational methods used to investigate key biological questions, as well as resources for training scientists at all stages of their careers.
The Benchmarking collection help readers decide between a number of methods which are developed to solve scientific problems.
Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform
Test accuracy of polymerase chain reaction methods against conventional diagnostic techniques for Cutaneous Leishmaniasis (CL) in patients with clinical or epidemiological suspicion of CL: Systematic review and meta-analysis
Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys
Prevalence and genetic profiles of isoniazid resistance in tuberculosis patients: A multicountry analysis of cross-sectional data
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