Deep image reconstruction from human brain activity

In this work, Fox et al. provide a new tool, the finite state projection based Fisher information matrix (FSP-FIM), which considers all cell-to-cell fluctuations measured in modern data sets, and can design optimal experiments under these conditions.

Sheikh, Harper et al. investigate how the neural processing in auditory cortex is shaped by the statistics of natural sounds. In summary, their model represents an alternative to linear approaches for biological auditory encoding while it captures salient data properties and links inhibitory subfields to explaining away effects.

To investigate the downstream signaling of a well-studied receptor tyrosine kinase, the insulin-like growth factor 1 receptor, Erickson et al. formulated and analyzed 45 cell line-specific mathematical models, which account for recruitment of 18 different binding partners to six sites of receptor autophosphorylation in IGF1R.