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Spatial regulation of immune response gene expression in fly larvae
3D rendering of a live fruit fly larva launching an immune response to bacterial infection. Green is a fluorescent reporter of an antimicrobial peptide called Diptericin. Magenta marks the nuclei of fat body cells, which produce large quantities of antimicrobial peptides in response to infection. Here, the response is spatially heterogeneous, with a small subset of cells (left region, which is the anterior fat body) producing most of the response. Image was taken with light sheet fluorescent microscopy. Schlomann et al. 2026
Image Credit: Brandon Schlomann