Table of Contents: December 2017

SYGL-1 (pink) and LST-1 (orange) proteins are expressed in the germline stem cell pool at the distal tip of the C. elegans gonad. These key stem cell regulators link Notch signaling from the niche with the downstream RNA regulatory network that controls stem cell self-renewal and differentiation. See Shin, Haupt et al.

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Image Credit: H. Shin and K. Haupt

Research Articles

Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose

Maikel Boot, Vincent J. C. van Winden, Marion Sparrius, Robert van de Weerd, Alexander Speer, Roy Ummels, Tige Rustad, David R. Sherman, Wilbert Bitter

The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage

Juan Lafuente-Barquero, Sarah Luke-Glaser, Marco Graf, Sonia Silva, Belén Gómez-González, Arianna Lockhart, Michael Lisby, Andrés Aguilera, Brian Luke

Integrated rare variant-based risk gene prioritization in disease case-control sequencing studies

Jhih-Rong Lin, Quanwei Zhang, Ying Cai, Bernice E. Morrow, Zhengdong D. Zhang

An essential regulatory function of the DnaK chaperone dictates the decision between proliferation and maintenance in Caulobacter crescentus

Frederic D. Schramm, Kristina Heinrich, Marietta Thüring, Jörg Bernhardt, Kristina Jonas

Loss-of-function of the ciliopathy protein Cc2d2a disorganizes the vesicle fusion machinery at the periciliary membrane and indirectly affects Rab8-trafficking in zebrafish photoreceptors

Irene Ojeda Naharros, Matthias Gesemann, José M. Mateos, Gery Barmettler, Austin Forbes, Urs Ziegler, Stephan C. F. Neuhauss, Ruxandra Bachmann-Gagescu

Parallel evolution of the POQR prolyl oligo peptidase gene conferring plant quantitative disease resistance

Thomas Badet, Derry Voisin, Malick Mbengue, Marielle Barascud, Justine Sucher, Pierre Sadon, Claudine Balagué, Dominique Roby, Sylvain Raffaele

FOXM1 activates AGR2 and causes progression of lung adenomas into invasive mucinous adenocarcinomas

David Milewski, David Balli, Vladimir Ustiyan, Tien Le, Hendrik Dienemann, Arne Warth, Kai Breuhahn, Jeffrey A. Whitsett, Vladimir V. Kalinichenko, Tanya V. Kalin

Binding of high mobility group A proteins to the mammalian genome occurs as a function of AT-content

Daniele F Colombo, Lukas Burger, Tuncay Baubec, Dirk Schübeler

Unlinking the methylome pattern from nucleotide sequence, revealed by large-scale in vivo genome engineering and methylome editing in medaka fish

Napo K. M. Cheung, Ryohei Nakamura, Ayako Uno, Masahiko Kumagai, Hiroto S. Fukushima, Shinichi Morishita, Hiroyuki Takeda

Regulation of the cohesin-loading factor NIPBL: Role of the lncRNA NIPBL-AS1 and identification of a distal enhancer element

Jessica Zuin, Valentina Casa, Jelena Pozojevic, Petros Kolovos, Mirjam C. G. N. van den Hout, Wilfred F. J. van Ijcken, Ilaria Parenti, Diana Braunholz, Yorann Baron, Erwan Watrin, Frank J. Kaiser, Kerstin S. Wendt

A conserved maternal-specific repressive domain in Zelda revealed by Cas9-mediated mutagenesis in Drosophila melanogaster

Danielle C. Hamm, Elizabeth D. Larson, Markus Nevil, Kelsey E. Marshall, Eliana R. Bondra, Melissa M. Harrison

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Leaf shedding as an anti-bacterial defense in Arabidopsis cauline leaves

O. Rahul Patharkar, Walter Gassmann, John C. Walker

Cell-to-cell variation and specialization in sugar metabolism in clonal bacterial populations

Nela Nikolic, Frank Schreiber, Alma Dal Co, Daniel J. Kiviet, Tobias Bergmiller, Sten Littmann, Marcel M. M. Kuypers, Martin Ackermann

Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway multiciliated cell differentiation

Saul S. Siller, Himanshu Sharma, Shuai Li, June Yang, Yong Zhang, Michael J. Holtzman, Wipawee Winuthayanon, Holly Colognato, Bernadette C. Holdener, Feng-Qian Li, Ken-Ichi Takemaru

MITF – A controls branching morphogenesis and nephron endowment

Aurélie Phelep, Denise Laouari, Kapil Bharti, Martine Burtin, Salvina Tammaccaro, Serge Garbay, Clément Nguyen, Florence Vasseur, Thomas Blanc, Sophie Berissi, Francina Langa-Vives, Evelyne Fischer, Anne Druilhe, Heinz Arnheiter, Gerard Friedlander, Marco Pontoglio, Fabiola Terzi

ciRS-7 exonic sequence is embedded in a long non-coding RNA locus

Steven P. Barrett, Kevin R. Parker, Caroline Horn, Miguel Mata, Julia Salzman

Adipose tissue deficiency of hormone-sensitive lipase causes fatty liver in mice

Bo Xia, Guo He Cai, Hao Yang, Shu Pei Wang, Grant A. Mitchell, Jiang Wei Wu

Host factors that promote retrotransposon integration are similar in distantly related eukaryotes

Sudhir Kumar Rai, Maya Sangesland, Michael Lee Jr., Caroline Esnault, Yujin Cui, Atreyi Ghatak Chatterjee, Henry L. Levin

An Arabidopsis Nucleoporin NUP85 modulates plant responses to ABA and salt stress

Yingfang Zhu, Bangshing Wang, Kai Tang, Chuan-Chih Hsu, Shaojun Xie, Hai Du, Yuting Yang, Weiguo Andy Tao, Jian-Kang Zhu

SYGL-1 and LST-1 link niche signaling to PUF RNA repression for stem cell maintenance in Caenorhabditis elegans

Heaji Shin, Kimberly A. Haupt, Aaron M. Kershner, Peggy Kroll-Conner, Marvin Wickens, Judith Kimble

A MIG-15/JNK-1 MAP kinase cascade opposes RPM-1 signaling in synapse formation and learning

Oliver Crawley, Andrew C. Giles, Muriel Desbois, Sudhanva Kashyap, Rayna Birnbaum, Brock Grill

In vivo zebrafish morphogenesis shows Cyp26b1 promotes tendon condensation and musculoskeletal patterning in the embryonic jaw

Patrick D. McGurk, Mary E. Swartz, Jessica W. Chen, Jenna L. Galloway, Johann K. Eberhart

The pea branching RMS2 gene encodes the PsAFB4/5 auxin receptor and is involved in an auxin-strigolactone regulation loop

Yasmine Ligerot, Alexandre de Saint Germain, Tanya Waldie, Christelle Troadec, Sylvie Citerne, Nikita Kadakia, Jean-Paul Pillot, Michael Prigge, Grégoire Aubert, Abdelhafid Bendahmane, Ottoline Leyser, Mark Estelle, Frédéric Debellé, Catherine Rameau

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