Advertisement
Table of Contents

May 2018

This image depicts the diversified colony morphologies of progeny generated from the coupled process of same- and opposite-sex mating in Candida tropicalis. Cells were grown on Lee's glucose medium containing the red dye phloxine B. See Du et al.

Download May's cover page.

Image Credit: Han Du, Qiushi Zheng

Review

Research Articles

TPP riboswitch-dependent regulation of an ancient thiamin transporter in Candida

Paul D. Donovan, Linda M. Holland, Lisa Lombardi, Aisling Y. Coughlan, Desmond G. Higgins, Kenneth H. Wolfe, Geraldine Butler

New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe

Takahisa Maki, Naoto Ogura, James E. Haber, Hiroshi Iwasaki, Geneviève Thon

Chromosome architecture constrains horizontal gene transfer in bacteria

Heather L. Hendrickson, Dominique Barbeau, Robin Ceschin, Jeffrey G. Lawrence

Differential strengths of molecular determinants guide environment specific mutational fates

Rohan Dandage, Rajesh Pandey, Gopal Jayaraj, Manish Rai, David Berger, Kausik Chakraborty

Spontaneous gain of susceptibility suggests a novel mechanism of resistance to hybrid dysgenesis in Drosophila virilis

Sergei Y. Funikov, Dina A. Kulikova, George S. Krasnov, Alexander P. Rezvykh, Lubov N. Chuvakova, Natalia G. Shostak, Elena S. Zelentsova, Justin P. Blumenstiel, Michael B. Evgen’ev

Auxin production in diploid microsporocytes is necessary and sufficient for early stages of pollen development

Xiaozhen Yao, Lei Tian, Jun Yang, Yan-Na Zhao, Ying-Xiu Zhu, Xinhua Dai, Yunde Zhao, Zhong-Nan Yang

Specific detection of fission yeast primary septum reveals septum and cleavage furrow ingression during early anaphase independent of mitosis completion

Juan Carlos G. Cortés, Mariona Ramos, Mami Konomi, Iris Barragán, M. Belén Moreno, María Alcaide-Gavilán, Sergio Moreno, Masako Osumi, Pilar Pérez, Juan Carlos Ribas

Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development

Seth D. Kasowitz, Jun Ma, Stephen J. Anderson, N. Adrian Leu, Yang Xu, Brian D. Gregory, Richard M. Schultz, P. Jeremy Wang

Adaptive genome duplication affects patterns of molecular evolution in Saccharomyces cerevisiae

Kaitlin J. Fisher, Sean W. Buskirk, Ryan C. Vignogna, Daniel A. Marad, Gregory I. Lang

Coordinated regulation of core and accessory genes in the multipartite genome of Sinorhizobium fredii

Jian Jiao, Meng Ni, Biliang Zhang, Ziding Zhang, J. Peter W. Young, Ting-Fung Chan, Wen Xin Chen, Hon-Ming Lam, Chang Fu Tian

Chromosome 1 licenses chromosome 2 replication in Vibrio cholerae by doubling the crtS gene dosage

Revathy Ramachandran, Peter N. Ciaccia, Tara A. Filsuf, Jyoti K. Jha, Dhruba K. Chattoraj

Yeast heterochromatin regulators Sir2 and Sir3 act directly at euchromatic DNA replication origins

Timothy A. Hoggard, FuJung Chang, Kelsey Rae Perry, Sandya Subramanian, Jessica Kenworthy, Julie Chueng, Erika Shor, Edel M. Hyland, Jef D. Boeke, Michael Weinreich, Catherine A. Fox

Ancestry-specific recent effective population size in the Americas

Sharon R. Browning, Brian L. Browning, Martha L. Daviglus, Ramon A. Durazo-Arvizu, Neil Schneiderman, Robert C. Kaplan, Cathy C. Laurie

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

Manuel A. Rivas, Brandon E. Avila, Jukka Koskela, Hailiang Huang, Christine Stevens, Matti Pirinen, Talin Haritunians, Benjamin M. Neale, Mitja Kurki, Andrea Ganna, Daniel Graham, Benjamin Glaser, Inga Peter, Gil Atzmon, Nir Barzilai, Adam P. Levine, Elena Schiff, Nikolas Pontikos, Ben Weisburd, Monkol Lek, Konrad J. Karczewski, Jonathan Bloom, Eric V. Minikel, Britt-Sabina Petersen, Laurent Beaugerie, Philippe Seksik, Jacques Cosnes, Stefan Schreiber, Bernd Bokemeyer, Johannes Bethge, International IBD Genetics Consortium, NIDDK IBD Genetics Consortium, T2D-GENES Consortium, Graham Heap, Tariq Ahmad, Vincent Plagnol, Anthony W. Segal, Stephan Targan, Dan Turner, Paivi Saavalainen, Martti Farkkila, Kimmo Kontula, Aarno Palotie, Steven R. Brant, Richard H. Duerr, Mark S. Silverberg, John D. Rioux, Rinse K. Weersma, Andre Franke, Luke Jostins, Carl A. Anderson, Jeffrey C. Barrett, Daniel G. MacArthur, Chaim Jalas, Harry Sokol, Ramnik J. Xavier, Ann Pulver, Judy H. Cho, Dermot P. B. McGovern, Mark J. Daly

MOF influences meiotic expansion of H2AX phosphorylation and spermatogenesis in mice

Hanwei Jiang, Qian Gao, Wei Zheng, Shi Yin, Liu Wang, Liangwen Zhong, Asim Ali, Teka Khan, Qiaomei Hao, Hui Fang, Xiaoling Sun, Peng Xu, Tej K. Pandita, Xiaohua Jiang, Qinghua Shi

The genomic landscape at a late stage of stickleback speciation: High genomic divergence interspersed by small localized regions of introgression

Mark Ravinet, Kohta Yoshida, Shuji Shigenobu, Atsushi Toyoda, Asao Fujiyama, Jun Kitano

Identity-by-descent analyses for measuring population dynamics and selection in recombining pathogens

Lyndal Henden, Stuart Lee, Ivo Mueller, Alyssa Barry, Melanie Bahlo

TGFβ signaling limits lineage plasticity in prostate cancer

Yi Hao, Glen A. Bjerke, Karolina Pietrzak, Tiffany A. Melhuish, Yu Han, Stephen D. Turner, Henry F. Frierson Jr, David Wotton

Elevated temperature increases meiotic crossover frequency via the interfering (Type I) pathway in Arabidopsis thaliana

Jennifer L. Modliszewski, Hongkuan Wang, Ashley R. Albright, Scott M. Lewis, Alexander R. Bennett, Jiyue Huang, Hong Ma, Yingxiang Wang, Gregory P. Copenhaver

A homozygous KAT2B variant modulates the clinical phenotype of ADD3 deficiency in humans and flies

Sara Gonçalves, Julie Patat, Maria Clara Guida, Noelle Lachaussée, Christelle Arrondel, Martin Helmstädter, Olivia Boyer, Olivier Gribouval, Marie-Claire Gubler, Geraldine Mollet, Marlène Rio, Marina Charbit, Christine Bole-Feysot, Patrick Nitschke, Tobias B. Huber, Patricia G. Wheeler, Devon Haynes, Jane Juusola, Thierry Billette de Villemeur, Caroline Nava, Alexandra Afenjar, Boris Keren, Rolf Bodmer, Corinne Antignac, Matias Simons

Related Articles

Condensin I protects meiotic cohesin from WAPL-1 mediated removal

Margarita R. Hernandez, Michael B. Davis, Jianhao Jiang, Elizabeth A. Brouhard, Aaron F. Severson, Györgyi Csankovszki

Distinctive types of postzygotic single-nucleotide mosaicisms in healthy individuals revealed by genome-wide profiling of multiple organs

August Yue Huang, Xiaoxu Yang, Sheng Wang, Xianing Zheng, Qixi Wu, Adam Yongxin Ye, Liping Wei

Prickle is phosphorylated by Nemo and targeted for degradation to maintain Prickle/Spiny-legs isoform balance during planar cell polarity establishment

Giovanna M. Collu, Andreas Jenny, Konstantin Gaengel, Ivana Mirkovic, Mei-ling Chin, Ursula Weber, Michael J. Smith, Marek Mlodzik

Defining ICR-Mo, an intrinsic colistin resistance determinant from Moraxella osloensis

Wenhui Wei, Swaminath Srinivas, Jingxia Lin, Zichen Tang, Shihua Wang, Saif Ullah, Vishnu Goutham Kota, Youjun Feng

mTOR signaling regulates central and peripheral circadian clock function

Chidambaram Ramanathan, Nimish D. Kathale, Dong Liu, Choogon Lee, David A. Freeman, John B. Hogenesch, Ruifeng Cao, Andrew C. Liu

Population-specific genetic modification of Huntington's disease in Venezuela

Michael J. Chao, Kyung-Hee Kim, Jun Wan Shin, Diane Lucente, Vanessa C. Wheeler, Hong Li, Jared C. Roach, Leroy Hood, Nancy S. Wexler, Laura B. Jardim, Peter Holmans, Lesley Jones, Michael Orth, Seung Kwak, Marcy E. MacDonald, James F. Gusella, Jong-Min Lee

Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration

Sheona Watson-Scales, Bernadett Kalmar, Eva Lana-Elola, Dorota Gibbins, Federica La Russa, Frances Wiseman, Matthew Williamson, Rachele Saccon, Amy Slender, Anna Olerinyova, Radma Mahmood, Emma Nye, Heather Cater, Sara Wells, Y. Eugene Yu, David L. H. Bennett, Linda Greensmith, Elizabeth M. C. Fisher, Victor L. J. Tybulewicz

Conditional genetic screen in Physcomitrella patens reveals a novel microtubule depolymerizing-end-tracking protein

Xinxin Ding, Leah M. Pervere, Carl Bascom Jr., Jeffrey P. Bibeau, Sakshi Khurana, Allison M. Butt, Robert G. Orr, Patrick J. Flaherty, Magdalena Bezanilla, Luis Vidali

Related Articles

Parallel altitudinal clines reveal trends in adaptive evolution of genome size in Zea mays

Paul Bilinski, Patrice S. Albert, Jeremy J. Berg, James A. Birchler, Mark N. Grote, Anne Lorant, Juvenal Quezada, Kelly Swarts, Jinliang Yang, Jeffrey Ross-Ibarra

Related Articles

SHOC1 is a ERCC4-(HhH)2-like protein, integral to the formation of crossover recombination intermediates during mammalian meiosis

Michel F. Guiraldelli, Anna Felberg, Luciana P. Almeida, Aniruddha Parikh, Rodrigo O. de Castro, Roberto J. Pezza

The receptor protein tyrosine phosphatase CLR-1 is required for synaptic partner recognition

Aruna Varshney, Kelli Benedetti, Katherine Watters, Raakhee Shankar, David Tatarakis, Doris Coto Villa, Khristina Magallanes, Venia Agenor, William Wung, Fatima Farah, Nebat Ali, Nghi Le, Jacqueline Pyle, Amber Farooqi, Zanett Kieu, Martina Bremer, Miri VanHoven

De novo and inherited private variants in MAP1B in periventricular nodular heterotopia

Erin L. Heinzen, Adam C. O'Neill, Xiaolin Zhu, Andrew S. Allen, Melanie Bahlo, Jamel Chelly, Ming Hui Chen, William B. Dobyns, Saskia Freytag, Renzo Guerrini, Richard J. Leventer, Annapurna Poduri, Stephen P. Robertson, Christopher A. Walsh, Mengqi Zhang, for the Epi4K Consortium, Epilepsy Phenome/Genome Project

Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage

Agnese Collino, Alberto Termanini, Paola Nicoli, Giuseppe Diaferia, Sara Polletti, Camilla Recordati, Vittoria Castiglioni, Donatella Caruso, Nico Mitro, Gioacchino Natoli, Serena Ghisletti

LncRNA Jpx induces Xist expression in mice using both trans and cis mechanisms

Sarah Carmona, Benjamin Lin, Tristan Chou, Katti Arroyo, Sha Sun

A coupled process of same- and opposite-sex mating generates polyploidy and genetic diversity in Candida tropicalis

Han Du, Qiushi Zheng, Jian Bing, Richard J. Bennett, Guanghua Huang

RIT1 controls actin dynamics via complex formation with RAC1/CDC42 and PAK1

Uta Meyer zum Büschenfelde, Laura Isabel Brandenstein, Leonie von Elsner, Kristina Flato, Tess Holling, Martin Zenker, Georg Rosenberger, Kerstin Kutsche

Gene regulatory network architecture in different developmental contexts influences the genetic basis of morphological evolution

Sebastian Kittelmann, Alexandra D. Buffry, Franziska A. Franke, Isabel Almudi, Marianne Yoth, Gonzalo Sabaris, Juan Pablo Couso, Maria D. S. Nunes, Nicolás Frankel, José Luis Gómez-Skarmeta, Jose Pueyo-Marques, Saad Arif, Alistair P. McGregor

The ARE-binding protein Tristetraprolin (TTP) is a novel target and mediator of calcineurin tumor suppressing function in the skin

Xunwei Wu, Alice Tommasi di Vignano, Qian Zhou, Piotr J. Michel-Dziunycz, Fuxiang Bai, Jun Mi, Jing Qin, Tingjian Zu, Günther F. L. Hofbauer

Role of duplicate genes in determining the tissue-selectivity of hereditary diseases

Ruth Barshir, Idan Hekselman, Netta Shemesh, Moran Sharon, Lena Novack, Esti Yeger-Lotem

Human local adaptation of the TRPM8 cold receptor along a latitudinal cline

Felix M. Key, Muslihudeen A. Abdul-Aziz, Roger Mundry, Benjamin M. Peter, Aarthi Sekar, Mauro D’Amato, Megan Y. Dennis, Joshua M. Schmidt, Aida M. Andrés

BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development

Kohei Kitami, Megumi Kitami, Masaru Kaku, Bin Wang, Yoshihiro Komatsu