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Journal Information

Scope

Genetics and genomics research has grown at a bewildering pace in the past 15 years. The techniques of these fields are being applied to a wealth of biological questions and experimental systems. PLOS Genetics reflects the full breadth and interdisciplinary nature of this research by publishing outstanding original contributions in all areas of biology.

PLOS Genetics publishes human studies, as well as research on model organisms—from mice and flies, to plants and bacteria. Our emphasis is on studies of broad interest that provide significant insight into a biological process or processes. Topics include (but are not limited to) gene discovery and function, population genetics, genome projects, comparative and functional genomics, medical genetics, disease biology, evolution, gene expression, complex traits, chromosome biology, and epigenetics.

Contents

PLOS Genetics features outstanding primary research articles, occasional Editorials and Topic Pages, and engaging InterviewsFormal CommentsViewpoints, Perspectives, and Reviews by invitation.

Criteria for Publication

To be considered for publication in PLOS Genetics, any given manuscript must satisfy the following criteria:

  • Originality

  • High importance to researchers in the field

  • Broad interest to researchers in genetics and genomics

  • Rigorous methodology

  • Substantial evidence for its conclusions

For manuscripts that focus on descriptive genomics, the PLOS Genetics editors are generally most enthusiastic about those that also include innovative theoretical treatment or follow-up experimentation that reveals novel and significant biological insight. For work in which disruption of gene function in model organisms plays an important role, compelling evidence of causality and specificity is required, generally supported by mutational analysis. Experiments based on alternative approaches, e.g., morpholinos, F0 gene editing, siRNA, or shRNA, are generally not sufficient unless accompanied by rigorous and thorough justification.

PLOS Genetics encourages researchers to share early versions of their manuscripts via preprint server, either before or after submission; posting to a preprint server will not preclude consideration of your manuscript.

Manuscripts rejected without external review

After initial evaluation by Senior Editors, a substantial proportion of manuscripts are rejected without external review. Common reasons for rejecting manuscripts without external review include:

  • Insufficient strength of advance

  • Absence of substantive insight into biology or disease pathogenesis
  • Incremental methods development studies that do not include an application to a biologic problem or system that reveals novel insight
  • Descriptive genomic or epigenomic studies that do not include follow-up experimental investigation

Editorial Oversight

To ensure the fairest and most objective decision-making, the editorial process is run as a partnership between the PLOS Genetics Editors-in-Chief, a team of Section Editors (SEs), and a group of academic experts who act as Associate Editors (AEs). These individuals are leaders in their fields and represent the full breadth of genetics and genomics.

Editors-in-Chief

Gregory S. Barsh
Gregory P. Copenhaver

Editorial Board

View the PLOS Genetics Editorial Board.

Submit Your Manuscript

For more information about submitting to PLOS Genetics, read our checklist for getting started and our guidelines for preparing a submission.

Open Access

PLOS applies the Creative Commons Attribution (CC BY) license to works we publish. This license was developed to facilitate open access – namely, free immediate access to, and unrestricted reuse of, original works of all types.

Under this license, authors agree to make articles legally available for reuse, without permission or fees, for virtually any purpose. Anyone may copy, distribute, or reuse these articles, as long as the author and original source are properly cited. Read PLOS’ licenses and copyright policy.

Journal Impact and Article Metrics

PLOS does not consider Impact Factor to be a reliable or useful metric to assess the performance of individual articles. PLOS supports DORA – the San Francisco Declaration on Research Assessment – and does not promote our journal Impact Factors. We will provide the metric to individuals when specifically requested.

PLOS promotes the use of Article-Level Metrics (ALMs), which enable scientists and the general public to engage more dynamically with published research. ALMs reflect the changing impact of research over time, incorporate academic as well as social impacts of research, and assess the impact of research before the accrual of academic citations. Read more about ALMs.

Publication Fees

PLOS Genetics publication fees are US$2350 per manuscript and will be billed upon acceptance. Authors’ ability to pay publication fees will never be a consideration in the decision whether to publish. Read more about publication fees and publication fee support.

Indexing and Archiving

See publishing details for all PLOS journal titles, including ISSN and indexing and archiving information.

About PLOS Journals

PLOS (Public Library of Science) publishes a suite of influential journals from all areas of science and medicine that contain rigorously reported, peer-reviewed Open Access research articles. The journals vary in their criteria for publication and, with the exception of PLOS ONE, also publish a variety of influential and educational non-research content. The journals are editorially independent. Read more about the PLOS suite of journals.

Contact

Visit the Contact page for details about whom to contact with different queries.

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