Table of Contents: January 2006

A sagittal section through an E12.5 Jag1 conditionally deleted mutant inner ear stained for SOX2, a marker of the prosensory domain. Signal is observed in the saccule (green) only, while other sensory regions are missing or reduced (nuclei are stained blue). These data establish the Notch ligand JAG1 as a protein required for early sensory development in the inner ear (see Kiernan et al.).

Image Credit: Photograph taken by Amy Kiernan using a Zeiss microscope and Zeiss Axiocam digital camera.


Genetic Analysis of the Cytoplasmic Dynein Subunit Families

K. Kevin Pfister, Paresh R Shah, Holger Hummerich, Andreas Russ, James Cotton, Azlina Ahmad Annuar, Stephen M King, Elizabeth M. C Fisher

Retroviral Elements and Their Hosts: Insertional Mutagenesis in the Mouse Germ Line

Irina A Maksakova, Mark T Romanish, Liane Gagnier, Catherine A Dunn, Louie N. van de Lagemaat, Dixie L Mager

Research Articles

Combined Expression Trait Correlations and Expression Quantitative Trait Locus Mapping

Hong Lan, Meng Chen, Jessica B Flowers, Brian S Yandell, Donnie S Stapleton, Christine M Mata, Eric Ton-Keen Mui, Matthew T Flowers, Kathryn L Schueler, Kenneth F Manly, Robert W Williams, Christina Kendziorski, Alan D Attie

Comparative Genomics of Multidrug Resistance in Acinetobacter baumannii

Pierre-Edouard Fournier, David Vallenet, Valérie Barbe, Stéphane Audic, Hiroyuki Ogata, Laurent Poirel, Hervé Richet, Catherine Robert, Sophie Mangenot, Chantal Abergel, Patrice Nordmann, Jean Weissenbach, Didier Raoult, Jean-Michel Claverie

Genetic Analysis of Completely Sequenced Disease-Associated MHC Haplotypes Identifies Shuffling of Segments in Recent Human History

James A Traherne, Roger Horton, Anne N Roberts, Marcos M Miretti, Matthew E Hurles, C. Andrew Stewart, Jennifer L Ashurst, Alexey M Atrazhev, Penny Coggill, Sophie Palmer, Jeff Almeida, Sarah Sims, Laurens G Wilming, Jane Rogers, Pieter J. de Jong, Mary Carrington, John F Elliott, Stephen Sawcer, John A Todd, John Trowsdale, Stephan Beck

Pol II–Expressed shRNA Knocks Down Sod2 Gene Expression and Causes Phenotypes of the Gene Knockout in Mice

Xu-Gang Xia, Hongxia Zhou, Enrique Samper, Simon Melov, Zuoshang Xu

Genome-Scale Identification of Membrane-Associated Human mRNAs

Maximilian Diehn, Ramona Bhattacharya, David Botstein, Patrick O Brown