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Table of Contents: October 2013

The photograph shows a female jewel wasp (Nasonia vitripennis) stinging a blowfly pupa, into which she lays her eggs. The jewel wasp is an emerging genetic model system. Genome-wide bisulfite sequencing reveals extensive DNA methylation over exons in the 5' portion of many protein coding genes in the jewel wasp. Methylated genes tend to show constitutive expression across developmental stages, whereas non-methylated genes have more stage-specific expression. Loss of methylation following gene duplication is associated with increased rates of evolution and more specialization in expression. See Wang et al.

Image Credit: Peter Koomen and Leo Beukeboom

Review

A Review of Bacteria-Animal Lateral Gene Transfer May Inform Our Understanding of Diseases like Cancer

Kelly M. Robinson, Karsten B. Sieber, Julie C. Dunning Hotopp

Research Articles

The Integrator Complex Subunit 6 (Ints6) Confines the Dorsal Organizer in Vertebrate Embryogenesis

Lee D. Kapp, Elliott W. Abrams, Florence L. Marlow, Mary C. Mullins

Genome Wide Analysis Reveals Zic3 Interaction with Distal Regulatory Elements of Stage Specific Developmental Genes in Zebrafish

Cecilia L. Winata, Igor Kondrychyn, Vibhor Kumar, Kandhadayar G. Srinivasan, Yuriy Orlov, Ashwini Ravishankar, Shyam Prabhakar, Lawrence W. Stanton, Vladimir Korzh, Sinnakaruppan Mathavan

Transcription Termination and Chimeric RNA Formation Controlled by Arabidopsis thaliana FPA

Céline Duc, Alexander Sherstnev, Christian Cole, Geoffrey J. Barton, Gordon G. Simpson

Dominant Mutations in S. cerevisiae PMS1 Identify the Mlh1-Pms1 Endonuclease Active Site and an Exonuclease 1-Independent Mismatch Repair Pathway

Catherine E. Smith, Marc L. Mendillo, Nikki Bowen, Hans Hombauer, Christopher S. Campbell, Arshad Desai, Christopher D. Putnam, Richard D. Kolodner

Condensin II Subunit dCAP-D3 Restricts Retrotransposon Mobilization in Drosophila Somatic Cells

Andrew T. Schuster, Kavitha Sarvepalli, Eain A. Murphy, Michelle S. Longworth

Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic

Fang Han, Juliette Faraco, Xiao Song Dong, Hanna M. Ollila, Ling Lin, Jing Li, Pei An, Shan Wang, Ke Wei Jiang, Zhan Cheng Gao, Long Zhao, Han Yan, Ya Nan Liu, Qing Hua Li, Xiao Zhe Zhang, Yan Hu, Jing Yu Wang, Yun Hui Lu, Chang Jun Lu, Wei Zhou, Joachim Hallmayer, Yu Shu Huang, Kingman P. Strohl, Thomas Pollmächer, Emmanuel Mignot

Coordination of Cell Proliferation and Cell Fate Determination by CES-1 Snail

Bo Yan, Nadin Memar, Julia Gallinger, Barbara Conradt

PNUTS/PP1 Regulates RNAPII-Mediated Gene Expression and Is Necessary for Developmental Growth

Anita Ciurciu, Louise Duncalf, Vincent Jonchere, Nick Lansdale, Olga Vasieva, Peter Glenday, Andreii Rudenko, Emese Vissi, Neville Cobbe, Luke Alphey, Daimark Bennett

tRNA Methyltransferase Homolog Gene TRMT10A Mutation in Young Onset Diabetes and Primary Microcephaly in Humans

Mariana Igoillo-Esteve, Anne Genin, Nelle Lambert, Julie Désir, Isabelle Pirson, Baroj Abdulkarim, Nicolas Simonis, Anais Drielsma, Lorella Marselli, Piero Marchetti, Pierre Vanderhaeghen, Décio L. Eizirik, Wim Wuyts, Cécile Julier, Ali J. Chakera, Sian Ellard, Andrew T. Hattersley, Marc Abramowicz, Miriam Cnop

Nuclear Fragile X Mental Retardation Protein Is localized to Cajal Bodies

Alain Y. Dury, Rachid El Fatimy, Sandra Tremblay, Timothy M. Rose, Jocelyn Côté, Paul De Koninck, Edouard W. Khandjian

Mobility of the Native Bacillus subtilis Conjugative Plasmid pLS20 Is Regulated by Intercellular Signaling

Praveen K. Singh, Gayetri Ramachandran, Ricardo Ramos-Ruiz, Ramón Peiró-Pastor, David Abia, Ling J. Wu, Wilfried J. J. Meijer

ALS-Associated FUS Mutations Result in Compromised FUS Alternative Splicing and Autoregulation

Yueqin Zhou, Songyan Liu, Guodong Liu, Arzu Öztürk, Geoffrey G. Hicks

Survival of the Replication Checkpoint Deficient Cells Requires MUS81-RAD52 Function

Ivana Murfuni, Giorgia Basile, Shyamal Subramanyam, Eva Malacaria, Margherita Bignami, Maria Spies, Annapaola Franchitto, Pietro Pichierri

Human Intellectual Disability Genes Form Conserved Functional Modules in Drosophila

Merel A. W. Oortveld, Shivakumar Keerthikumar, Martin Oti, Bonnie Nijhof, Ana Clara Fernandes, Korinna Kochinke, Anna Castells-Nobau, Eva van Engelen, Thijs Ellenkamp, Lilian Eshuis, Anne Galy, Hans van Bokhoven, Bianca Habermann, Han G. Brunner, Christiane Zweier, Patrik Verstreken, Martijn A. Huynen, Annette Schenck

FliZ Is a Global Regulatory Protein Affecting the Expression of Flagellar and Virulence Genes in Individual Xenorhabdus nematophila Bacterial Cells

Grégory Jubelin, Anne Lanois, Dany Severac, Stéphanie Rialle, Cyrille Longin, Sophie Gaudriault, Alain Givaudan

Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates

David M. Evans, Marie Jo A. Brion, Lavinia Paternoster, John P. Kemp, George McMahon, Marcus Munafò, John B. Whitfield, Sarah E. Medland, Grant W. Montgomery, The GIANT consortium, The CRP consortium, The TAG Consortium, Nicholas J. Timpson, Beate St. Pourcain, Debbie A. Lawlor, Nicholas G. Martin, Abbas Dehghan, Joel Hirschhorn, George Davey Smith

Mismatch Repair Genes Mlh1 and Mlh3 Modify CAG Instability in Huntington's Disease Mice: Genome-Wide and Candidate Approaches

Ricardo Mouro Pinto, Ella Dragileva, Andrew Kirby, Alejandro Lloret, Edith Lopez, Jason St. Claire, Gagan B. Panigrahi, Caixia Hou, Kim Holloway, Tammy Gillis, Jolene R. Guide, Paula E. Cohen, Guo-Min Li, Christopher E. Pearson, Mark J. Daly, Vanessa C. Wheeler

The Inactivation of Arx in Pancreatic α-Cells Triggers Their Neogenesis and Conversion into Functional β-Like Cells

Monica Courtney, Elisabet Gjernes, Noémie Druelle, Christophe Ravaud, Andhira Vieira, Nouha Ben-Othman, Anja Pfeifer, Fabio Avolio, Gunter Leuckx, Sandra Lacas-Gervais, Fanny Burel-Vandenbos, Damien Ambrosetti, Jacob Hecksher-Sorensen, Philippe Ravassard, Harry Heimberg, Ahmed Mansouri, Patrick Collombat

Co-evolution of Human Leukocyte Antigen (HLA) Class I Ligands with Killer-Cell Immunoglobulin-Like Receptors (KIR) in a Genetically Diverse Population of Sub-Saharan Africans

Paul J. Norman, Jill A. Hollenbach, Neda Nemat-Gorgani, Lisbeth A. Guethlein, Hugo G. Hilton, Marcelo J. Pando, Kwadwo A. Koram, Eleanor M. Riley, Laurent Abi-Rached, Peter Parham

Two Portable Recombination Enhancers Direct Donor Choice in Fission Yeast Heterochromatin

Tadas Jakočiūnas, Lærke Rebekka Holm, Janne Verhein-Hansen, Ala Trusina, Geneviève Thon

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Partial Deletion of Chromosome 8 β-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice

Yu S. Zhou, Sheila Webb, Laura Lettice, Steve Tardif, Fiona Kilanowski, Christine Tyrrell, Heather MacPherson, Fiona Semple, Peter Tennant, Tina Baker, Alan Hart, Paul Devenney, Paul Perry, Tracey Davey, Perdita Barran, Chris L. Barratt, Julia R. Dorin

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Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture

Lea K. Davis, Dongmei Yu, Clare L. Keenan, Eric R. Gamazon, Anuar I. Konkashbaev, Eske M. Derks, Benjamin M. Neale, Jian Yang, S. Hong Lee, Patrick Evans, Cathy L. Barr, Laura Bellodi, Fortu Benarroch, Gabriel Bedoya Berrio, Oscar J. Bienvenu, Michael H. Bloch, Rianne M. Blom, Ruth D. Bruun, Cathy L. Budman, Beatriz Camarena, Desmond Campbell, Carolina Cappi, Julio C. Cardona Silgado, Danielle C. Cath, Maria C. Cavallini, Denise A. Chavira, Sylvain Chouinard, David V. Conti, Edwin H. Cook, Vladimir Coric, Bernadette A. Cullen, Dieter Deforce, Richard Delorme, Yves Dion, Christopher K. Edlund, Karin Egberts, Peter Falkai, Thomas V. Fernandez, Patience J. Gallagher, Helena Garrido, Daniel Geller, Simon L. Girard, Hans J. Grabe, Marco A. Grados, Benjamin D. Greenberg, Varda Gross-Tsur, Stephen Haddad, Gary A. Heiman, Sian M. J. Hemmings, Ana G. Hounie, Cornelia Illmann, Joseph Jankovic, Michael A. Jenike, James L. Kennedy, Robert A. King, Barbara Kremeyer, Roger Kurlan, Nuria Lanzagorta, Marion Leboyer, James F. Leckman, Leonhard Lennertz, Chunyu Liu, Christine Lochner, Thomas L. Lowe, Fabio Macciardi, James T. McCracken, Lauren M. McGrath, Sandra C. Mesa Restrepo, Rainald Moessner, Jubel Morgan, Heike Muller, Dennis L. Murphy, Allan L. Naarden, William Cornejo Ochoa, Roel A. Ophoff, Lisa Osiecki, Andrew J. Pakstis, Michele T. Pato, Carlos N. Pato, John Piacentini, Christopher Pittenger, Yehuda Pollak, Scott L. Rauch, Tobias J. Renner, Victor I. Reus, Margaret A. Richter, Mark A. Riddle, Mary M. Robertson, Roxana Romero, Maria C. Rosàrio, David Rosenberg, Guy A. Rouleau, Stephan Ruhrmann, Andres Ruiz-Linares, Aline S. Sampaio, Jack Samuels, Paul Sandor, Brooke Sheppard, Harvey S. Singer, Jan H. Smit, Dan J. Stein, E. Strengman, Jay A. Tischfield, Ana V. Valencia Duarte, Homero Vallada, Filip Van Nieuwerburgh, Jeremy Veenstra-VanderWeele, Susanne Walitza, Ying Wang, Jens R. Wendland, Herman G. M. Westenberg, Yin Yao Shugart, Euripedes C. Miguel, William McMahon, Michael Wagner, Humberto Nicolini, Danielle Posthuma, Gregory L. Hanna, Peter Heutink, Damiaan Denys, Paul D. Arnold, Ben A. Oostra, Gerald Nestadt, Nelson B. Freimer, David L. Pauls, Naomi R. Wray, S. Evelyn Stewart, Carol A. Mathews, James A. Knowles, Nancy J. Cox, Jeremiah M. Scharf

Correlated Occurrence and Bypass of Frame-Shifting Insertion-Deletions (InDels) to Give Functional Proteins

Liat Rockah-Shmuel, Ágnes Tóth-Petróczy, Asaf Sela, Omri Wurtzel, Rotem Sorek, Dan S. Tawfik

A Reversible Histone H3 Acetylation Cooperates with Mismatch Repair and Replicative Polymerases in Maintaining Genome Stability

Lyudmila Y. Kadyrova, Tony M. Mertz, Yu Zhang, Matthew R. Northam, Ziwei Sheng, Kirill S. Lobachev, Polina V. Shcherbakova, Farid A. Kadyrov

Acceleration of the Glycolytic Flux by Steroid Receptor Coactivator-2 Is Essential for Endometrial Decidualization

Ramakrishna Kommagani, Maria M. Szwarc, Ertug Kovanci, William E. Gibbons, Nagireddy Putluri, Suman Maity, Chad J. Creighton, Arun Sreekumar, Francesco J. DeMayo, John P. Lydon, Bert W. O'Malley

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Robust Demographic Inference from Genomic and SNP Data

Laurent Excoffier, Isabelle Dupanloup, Emilia Huerta-Sánchez, Vitor C. Sousa, Matthieu Foll

Genetic Regulation of Caenorhabditis elegans Lysosome Related Organelle Function

Alexander A. Soukas, Christopher E. Carr, Gary Ruvkun

Loss of miR-10a Activates Lpo and Collaborates with Activated Wnt Signaling in Inducing Intestinal Neoplasia in Female Mice

Gustavo Stadthagen, Disa Tehler, Nina Molin Høyland-Kroghsbo, Jiayu Wen, Anders Krogh, Klaus T. Jensen, Eric Santoni-Rugiu, Lars H. Engelholm, Anders H. Lund

Systematic Unraveling of the Unsolved Pathway of Nicotine Degradation in Pseudomonas

Hongzhi Tang, Lijuan Wang, Weiwei Wang, Hao Yu, Kunzhi Zhang, Yuxiang Yao, Ping Xu

Specific Tandem Repeats Are Sufficient for Paramutation-Induced Trans-Generational Silencing

Christiane L. Belele, Lyudmila Sidorenko, Maike Stam, Rechien Bader, Mario A. Arteaga-Vazquez, Vicki L. Chandler

The Bacterial Response Regulator ArcA Uses a Diverse Binding Site Architecture to Regulate Carbon Oxidation Globally

Dan M. Park, Md. Sohail Akhtar, Aseem Z. Ansari, Robert Landick, Patricia J. Kiley

A Novel Intra-U1 snRNP Cross-Regulation Mechanism: Alternative Splicing Switch Links U1C and U1-70K Expression

Tanja Dorothe Rösel-Hillgärtner, Lee-Hsueh Hung, Ekaterina Khrameeva, Patrick Le Querrec, Mikhail S. Gelfand, Albrecht Bindereif

The Transacting Factor CBF-A/Hnrnpab Binds to the A2RE/RTS Element of Protamine 2 mRNA and Contributes to Its Translational Regulation during Mouse Spermatogenesis

Nanaho Fukuda, Tomoyuki Fukuda, John Sinnamon, Abrahan Hernandez-Hernandez, Manizheh Izadi, Chandrasekhar S. Raju, Kevin Czaplinski, Piergiorgio Percipalle

De Novo ORFs in Drosophila Are Important to Organismal Fitness and Evolved Rapidly from Previously Non-coding Sequences

Josephine A. Reinhardt, Betty M. Wanjiru, Alicia T. Brant, Perot Saelao, David J. Begun, Corbin D. Jones

Yeast Tdh3 (Glyceraldehyde 3-Phosphate Dehydrogenase) Is a Sir2-Interacting Factor That Regulates Transcriptional Silencing and rDNA Recombination

Alison E. Ringel, Rebecca Ryznar, Hannah Picariello, Kuan-lin Huang, Asmitha G. Lazarus, Scott G. Holmes

Eleven Candidate Susceptibility Genes for Common Familial Colorectal Cancer

Alexandra E. Gylfe, Riku Katainen, Johanna Kondelin, Tomas Tanskanen, Tatiana Cajuso, Ulrika Hänninen, Jussi Taipale, Minna Taipale, Laura Renkonen-Sinisalo, Heikki Järvinen, Jukka-Pekka Mecklin, Outi Kilpivaara, Esa Pitkänen, Pia Vahteristo, Sari Tuupanen, Auli Karhu, Lauri A. Aaltonen

Cooperation between RUNX1-ETO9a and Novel Transcriptional Partner KLF6 in Upregulation of Alox5 in Acute Myeloid Leukemia

Russell C. DeKelver, Benjamin Lewin, Kentson Lam, Yukiko Komeno, Ming Yan, Chandler Rundle, Miao-Chia Lo, Dong-Er Zhang

Natural Genetic Variation of Integrin Alpha L (Itgal) Modulates Ischemic Brain Injury in Stroke

Sehoon Keum, Han Kyu Lee, Pei-Lun Chu, Matthew J. Kan, Min-Nung Huang, Carol J. Gallione, Michael D. Gunn, Donald C. Lo, Douglas A. Marchuk

Rad52 Sumoylation Prevents the Toxicity of Unproductive Rad51 Filaments Independently of the Anti-Recombinase Srs2

Aline Esta, Emilie Ma, Pauline Dupaigne, Laurent Maloisel, Raphaël Guerois, Eric Le Cam, Xavier Veaute, Eric Coïc

Reverse PCA, a Systematic Approach for Identifying Genes Important for the Physical Interaction between Protein Pairs

Ifat Lev, Marina Volpe, Liron Goor, Nelly Levinton, Liach Emuna, Shay Ben-Aroya

Inhibition of the Mitotic Exit Network in Response to Damaged Telomeres

Mauricio Valerio-Santiago, Ana Isabel de los Santos-Velázquez, Fernando Monje-Casas

Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection

Nicholas J. Croucher, Andrea M. Mitchell, Katherine A. Gould, Donald Inverarity, Lars Barquist, Theresa Feltwell, Maria C. Fookes, Simon R. Harris, Janina Dordel, Susannah J. Salter, Sarah Browall, Helena Zemlickova, Julian Parkhill, Staffan Normark, Birgitta Henriques-Normark, Jason Hinds, Tim J. Mitchell, Stephen D. Bentley

Preferential Binding to Elk-1 by SLE-Associated IL10 Risk Allele Upregulates IL10 Expression

Daisuke Sakurai, Jian Zhao, Yun Deng, Jennifer A. Kelly, Elizabeth E. Brown, John B. Harley, Sang-Cheol Bae, Marta E. Alarcόn-Riquelme, on behalf of the BIOLUPUS and GENLES networks, Jeffrey C. Edberg, Robert P. Kimberly, Rosalind Ramsey-Goldman, Michelle A. Petri, John D. Reveille, Luis M. Vilá, Graciela S. Alarcón, Kenneth M. Kaufman, Timothy J. Vyse, Chaim O. Jacob, Patrick M. Gaffney, Kathy Moser Sivils, Judith A. James, Diane L. Kamen, Gary S. Gilkeson, Timothy B. Niewold, Joan T. Merrill, R. Hal Scofield, Lindsey A. Criswell, Anne M. Stevens, Susan A. Boackle, Jae-Hoon Kim, Jiyoung Choi, Bernardo A. Pons-Estel, on behalf of the Argentine Collaborative Group, Barry I. Freedman, Juan-Manuel Anaya, Javier Martin, C. Yung Yu, Deh-Ming Chang, Yeong Wook Song, Carl D. Langefeld, Weiling Chen, Jennifer M. Grossman, Rita M. Cantor, Bevra H. Hahn, Betty P. Tsao

Function and Evolution of DNA Methylation in Nasonia vitripennis

Xu Wang, David Wheeler, Amanda Avery, Alfredo Rago, Jeong-Hyeon Choi, John K. Colbourne, Andrew G. Clark, John H. Werren

A Novel Actin mRNA Splice Variant Regulates ACTG1 Expression

Meghan C. Drummond, Karen H. Friderici

Genome-Wide Analysis of Cell Type-Specific Gene Transcription during Spore Formation in Clostridium difficile

Laure Saujet, Fátima C. Pereira, Monica Serrano, Olga Soutourina, Marc Monot, Pavel V. Shelyakin, Mikhail S. Gelfand, Bruno Dupuy, Adriano O. Henriques, Isabelle Martin-Verstraete

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Identification of 526 Conserved Metazoan Genetic Innovations Exposes a New Role for Cofactor E-like in Neuronal Microtubule Homeostasis

Melissa Y. Frédéric, Victor F. Lundin, Matthew D. Whiteside, Juan G. Cueva, Domena K. Tu, S. Y. Catherine Kang, Hansmeet Singh, David L. Baillie, Harald Hutter, Miriam B. Goodman, Fiona S. L. Brinkman, Michel R. Leroux

Distinct Regulatory Mechanisms Act to Establish and Maintain Pax3 Expression in the Developing Neural Tube

Steven Moore, Vanessa Ribes, Javier Terriente, David Wilkinson, Frédéric Relaix, James Briscoe

Both Rare and De Novo Copy Number Variants Are Prevalent in Agenesis of the Corpus Callosum but Not in Cerebellar Hypoplasia or Polymicrogyria

Samin A. Sajan, Liliana Fernandez, Sahar Esmaeeli Nieh, Eric Rider, Polina Bukshpun, Mari Wakahiro, Susan L. Christian, Jean-Baptiste Rivière, Christopher T. Sullivan, Jyotsna Sudi, Michael J. Herriges, Alexander R. Paciorkowski, A. James Barkovich, Joseph T. Glessner, Kathleen J. Millen, Hakon Hakonarson, William B. Dobyns, Elliott H. Sherr

Direct Monitoring of the Strand Passage Reaction of DNA Topoisomerase II Triggers Checkpoint Activation

Katherine L. Furniss, Hung-Ji Tsai, Jo Ann W. Byl, Andrew B. Lane, Amit C. Vas, Wei-Shan Hsu, Neil Osheroff, Duncan J. Clarke

The Serum Resistome of a Globally Disseminated Multidrug Resistant Uropathogenic Escherichia coli Clone

Minh-Duy Phan, Kate M. Peters, Sohinee Sarkar, Samuel W. Lukowski, Luke P. Allsopp, Danilo Gomes Moriel, Maud E. S. Achard, Makrina Totsika, Vikki M. Marshall, Mathew Upton, Scott A. Beatson, Mark A. Schembri

Chimeric Protein Complexes in Hybrid Species Generate Novel Phenotypes

Elzbieta M. Piatkowska, Samina Naseeb, David Knight, Daniela Delneri

SUMO Localizes to the Central Element of Synaptonemal Complex and Is Required for the Full Synapsis of Meiotic Chromosomes in Budding Yeast

Karen Voelkel-Meiman, Louis F. Taylor, Pritam Mukherjee, Neil Humphryes, Hideo Tsubouchi, Amy J. MacQueen

Incorporating Motif Analysis into Gene Co-expression Networks Reveals Novel Modular Expression Pattern and New Signaling Pathways

Shisong Ma, Smit Shah, Hans J. Bohnert, Michael Snyder, Savithramma P. Dinesh-Kumar

Coordinate Regulation of Mature Dopaminergic Axon Morphology by Macroautophagy and the PTEN Signaling Pathway

Keiichi Inoue, Joanne Rispoli, Lichuan Yang, David MacLeod, M. Flint Beal, Eric Klann, Asa Abeliovich

A GDF5 Point Mutation Strikes Twice - Causing BDA1 and SYNS2

Elisa Degenkolbe, Jana König, Julia Zimmer, Maria Walther, Carsten Reißner, Joachim Nickel, Frank Plöger, Jelena Raspopovic, James Sharpe, Katarina Dathe, Jacqueline T. Hecht, Stefan Mundlos, Sandra C. Doelken, Petra Seemann

A Mutation in the SUV39H2 Gene in Labrador Retrievers with Hereditary Nasal Parakeratosis (HNPK) Provides Insights into the Epigenetics of Keratinocyte Differentiation

Vidhya Jagannathan, Jeanette Bannoehr, Philippe Plattet, Regula Hauswirth, Cord Drögemüller, Michaela Drögemüller, Dominique J. Wiener, Marcus Doherr, Marta Owczarek-Lipska, Arnaud Galichet, Monika M. Welle, Katarina Tengvall, Kerstin Bergvall, Hannes Lohi, Silvia Rüfenacht, Monika Linek, Manon Paradis, Eliane J. Müller, Petra Roosje, Tosso Leeb

Genetic Architecture of Skewed X Inactivation in the Laboratory Mouse

John D. Calaway, Alan B. Lenarcic, John P. Didion, Jeremy R. Wang, Jeremy B. Searle, Leonard McMillan, William Valdar, Fernando Pardo-Manuel de Villena

Stimulation of mTORC1 with L-leucine Rescues Defects Associated with Roberts Syndrome

Baoshan Xu, Kenneth K. Lee, Lily Zhang, Jennifer L. Gerton