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Table of Contents

August 2014

The feather is an excellent model for evolution and development. The Silkie chicken breed is fixed for the silky-feather mutation, and is named based on the fascinating silky-feather phenotype. In contrast to the closed pennaceous feathers in the wild-type, the silky-feathers lack hooklets on the distal barbules and fail to form the vane. In this issue, Feng et al. report the identification of the silky-feather mutation located in the promoter of PDSS2. This is the first report of a feather structure variation associated with PDSS2 and provides new insight into the feather morphogenesis.

Image Credit: Chungang Feng, China Agricultural University, Beijing, China

Review

Human Social Genomics

Steven W. Cole

Research Articles

The Genomic Architecture of Population Divergence between Subspecies of the European Rabbit

Miguel Carneiro, Frank W. Albert, Sandra Afonso, Ricardo J. Pereira, Hernan Burbano, Rita Campos, José Melo-Ferreira, Jose A. Blanco-Aguiar, Rafael Villafuerte, Michael W. Nachman, Jeffrey M. Good, Nuno Ferrand

A Population Genetic Signal of Polygenic Adaptation

Jeremy J. Berg, Graham Coop

Branch Migration Prevents DNA Loss during Double-Strand Break Repair

Julia S. P. Mawer, David R. F. Leach

Response Regulator Heterodimer Formation Controls a Key Stage in Streptomyces Development

Mahmoud M. Al-Bassam, Maureen J. Bibb, Matthew J. Bush, Govind Chandra, Mark J. Buttner

Dysfunction of the CNS-Heart Axis in Mouse Models of Huntington's Disease

Michal Mielcarek, Linda Inuabasi, Marie K. Bondulich, Thomas Muller, Georgina F. Osborne, Sophie A. Franklin, Donna L. Smith, Andreas Neueder, Jim Rosinski, Ivan Rattray, Andrea Protti, Gillian P. Bates

KDM6 Demethylase Independent Loss of Histone H3 Lysine 27 Trimethylation during Early Embryonic Development

Karl B. Shpargel, Joshua Starmer, Della Yee, Michael Pohlers, Terry Magnuson

Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress

Ildiko Kasza, Yewseok Suh, Damian Wollny, Rod J. Clark, Avtar Roopra, Ricki J. Colman, Ormond A. MacDougald, Timothy A. Shedd, David W. Nelson, Mei-I Yen, Chi-Liang Eric Yen, Caroline M. Alexander

Evidence for Divisome Localization Mechanisms Independent of the Min System and SlmA in Escherichia coli

Matthew W. Bailey, Paola Bisicchia, Boyd T. Warren, David J. Sherratt, Jaan Männik

A System for Genome-Wide Histone Variant Dynamics In ES Cells Reveals Dynamic MacroH2A2 Replacement at Promoters

Ozlem Yildirim, Jui-Hung Hung, Ryan J. Cedeno, Zhiping Weng, Christopher J. Lengner, Oliver J. Rando

Genome-Wide Patterns of Genetic Variation within and among Alternative Selective Regimes

Yuheng Huang, Stephen I. Wright, Aneil F. Agrawal

Demography and the Age of Rare Variants

Iain Mathieson, Gil McVean

The Response to High CO2 Levels Requires the Neuropeptide Secretion Component HID-1 to Promote Pumping Inhibition

Kfir Sharabi, Chayki Charar, Nurit Friedman, Inbar Mizrahi, Alon Zaslaver, Jacob I. Sznajder, Yosef Gruenbaum

Retinoic Acid Activates Two Pathways Required for Meiosis in Mice

Jana Koubova, Yueh-Chiang Hu, Tanmoy Bhattacharyya, Y. Q. Shirleen Soh, Mark E. Gill, Mary L. Goodheart, Cathryn A. Hogarth, Michael D. Griswold, David C. Page

Comprehensive Identification of Single Nucleotide Polymorphisms Associated with Beta-lactam Resistance within Pneumococcal Mosaic Genes

Claire Chewapreecha, Pekka Marttinen, Nicholas J. Croucher, Susannah J. Salter, Simon R. Harris, Alison E. Mather, William P. Hanage, David Goldblatt, Francois H. Nosten, Claudia Turner, Paul Turner, Stephen D. Bentley, Julian Parkhill

A Genetic Strategy to Measure Circulating Drosophila Insulin Reveals Genes Regulating Insulin Production and Secretion

Sangbin Park, Ronald W. Alfa, Sydni M. Topper, Grace E. S. Kim, Lutz Kockel, Seung K. Kim

Arabidopsis miR171-Targeted Scarecrow-Like Proteins Bind to GT cis-Elements and Mediate Gibberellin-Regulated Chlorophyll Biosynthesis under Light Conditions

Zhaoxue Ma, Xupeng Hu, Wenjuan Cai, Weihua Huang, Xin Zhou, Qian Luo, Hongquan Yang, Jiawei Wang, Jirong Huang

Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

Maggie C. Y. Ng, Daniel Shriner, Brian H. Chen, Jiang Li, Wei-Min Chen, Xiuqing Guo, Jiankang Liu, Suzette J. Bielinski, Lisa R. Yanek, Michael A. Nalls, Mary E. Comeau, Laura J. Rasmussen-Torvik, Richard A. Jensen, Daniel S. Evans, Yan V. Sun, Ping An, Sanjay R. Patel, Yingchang Lu, Jirong Long, Loren L. Armstrong, Lynne Wagenknecht, Lingyao Yang, Beverly M. Snively, Nicholette D. Palmer, Poorva Mudgal, Carl D. Langefeld, Keith L. Keene, Barry I. Freedman, Josyf C. Mychaleckyj, Uma Nayak, Leslie J. Raffel, Mark O. Goodarzi, Y-D Ida Chen, Herman A. Taylor Jr., Adolfo Correa, Mario Sims, David Couper, James S. Pankow, Eric Boerwinkle, Adebowale Adeyemo, Ayo Doumatey, Guanjie Chen, Rasika A. Mathias, Dhananjay Vaidya, Andrew B. Singleton, Alan B. Zonderman, Robert P. Igo Jr., John R. Sedor, the FIND Consortium, Edmond K. Kabagambe, David S. Siscovick, Barbara McKnight, Kenneth Rice, Yongmei Liu, Wen-Chi Hsueh, Wei Zhao, Lawrence F. Bielak, Aldi Kraja, Michael A. Province, Erwin P. Bottinger, Omri Gottesman, Qiuyin Cai, Wei Zheng, William J. Blot, William L. Lowe, Jennifer A. Pacheco, Dana C. Crawford, the eMERGE Consortium, the DIAGRAM Consortium, Elin Grundberg, the MuTHER Consortium, Stephen S. Rich, M. Geoffrey Hayes, Xiao-Ou Shu, Ruth J. F. Loos, Ingrid B. Borecki, Patricia A. Peyser, Steven R. Cummings, Bruce M. Psaty, Myriam Fornage, Sudha K. Iyengar, Michele K. Evans, Diane M. Becker, W. H. Linda Kao, James G. Wilson, Jerome I. Rotter, Michèle M. Sale, Simin Liu, Charles N. Rotimi, Donald W. Bowden, for the MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium

Asymmetric Division and Differential Gene Expression during a Bacterial Developmental Program Requires DivIVA

Prahathees Eswaramoorthy, Peter W. Winter, Peter Wawrzusin, Andrew G. York, Hari Shroff, Kumaran S. Ramamurthi

Inference of Transposable Element Ancestry

Aaron C. Wacholder, Corey Cox, Thomas J. Meyer, Robert P. Ruggiero, Vijetha Vemulapalli, Annette Damert, Lucia Carbone, David D. Pollock

The Population Genetics of Evolutionary Rescue

H. Allen Orr, Robert L. Unckless

An Otx/Nodal Regulatory Signature for Posterior Neural Development in Ascidians

Agnès Roure, Patrick Lemaire, Sébastien Darras

A Transposable Element Insertion Confers Xenobiotic Resistance in Drosophila

Lidia Mateo, Anna Ullastres, Josefa González

EVA-1 Functions as an UNC-40 Co-receptor to Enhance Attraction to the MADD-4 Guidance Cue in Caenorhabditis elegans

Kevin Ka Ming Chan, Ashwin Seetharaman, Rachel Bagg, Guillermo Selman, Yuqian Zhang, Joowan Kim, Peter J. Roy

Patterns of Admixture and Population Structure in Native Populations of Northwest North America

Paul Verdu, Trevor J. Pemberton, Romain Laurent, Brian M. Kemp, Angelica Gonzalez-Oliver, Clara Gorodezky, Cris E. Hughes, Milena R. Shattuck, Barbara Petzelt, Joycelynn Mitchell, Harold Harry, Theresa William, Rosita Worl, Jerome S. Cybulski, Noah A. Rosenberg, Ripan S. Malhi

Phosphorylation of a Central Clock Transcription Factor Is Required for Thermal but Not Photic Entrainment

Euna Lee, Eun Hee Jeong, Hyun-Jeong Jeong, Evrim Yildirim, Jens T. Vanselow, Fanny Ng, Yixiao Liu, Guruswamy Mahesh, Achim Kramer, Paul E. Hardin, Isaac Edery, Eun Young Kim

Conditional Inactivation of Upstream Binding Factor Reveals Its Epigenetic Functions and the Existence of a Somatic Nucleolar Precursor Body

Nourdine Hamdane, Victor Y. Stefanovsky, Michel G. Tremblay, Attila Németh, Eric Paquet, Frédéric Lessard, Elaine Sanij, Ross Hannan, Tom Moss

Transcriptome Sequencing from Diverse Human Populations Reveals Differentiated Regulatory Architecture

Alicia R. Martin, Helio A. Costa, Tuuli Lappalainen, Brenna M. Henn, Jeffrey M. Kidd, Muh-Ching Yee, Fabian Grubert, Howard M. Cann, Michael Snyder, Stephen B. Montgomery, Carlos D. Bustamante

Genetic Deletion of SEPT7 Reveals a Cell Type-Specific Role of Septins in Microtubule Destabilization for the Completion of Cytokinesis

Manoj B. Menon, Akihiro Sawada, Anuhar Chaturvedi, Pooja Mishra, Karin Schuster-Gossler, Melanie Galla, Axel Schambach, Achim Gossler, Reinhold Förster, Michael Heuser, Alexey Kotlyarov, Makoto Kinoshita, Matthias Gaestel

Gene Expansion Shapes Genome Architecture in the Human Pathogen Lichtheimia corymbifera: An Evolutionary Genomics Analysis in the Ancient Terrestrial Mucorales (Mucoromycotina)

Volker U. Schwartze, Sascha Winter, Ekaterina Shelest, Marina Marcet-Houben, Fabian Horn, Stefanie Wehner, Jörg Linde, Vito Valiante, Michael Sammeth, Konstantin Riege, Minou Nowrousian, Kerstin Kaerger, Ilse D. Jacobsen, Manja Marz, Axel A. Brakhage, Toni Gabaldón, Sebastian Böcker, Kerstin Voigt

Related Articles

Pooled Segregant Sequencing Reveals Genetic Determinants of Yeast Pseudohyphal Growth

Qingxuan Song, Cole Johnson, Thomas E. Wilson, Anuj Kumar

Wnt-Mediated Repression via Bipartite DNA Recognition by TCF in the Drosophila Hematopoietic System

Chen U. Zhang, Timothy A. Blauwkamp, Peter E. Burby, Ken M. Cadigan

Functional Specialization Among Members Of Knickkopf Family Of Proteins In Insect Cuticle Organization

Sujata S. Chaudhari, Bernard Moussian, Charles A. Specht, Yasuyuki Arakane, Karl J. Kramer, Richard W. Beeman, Subbaratnam Muthukrishnan

Global Genetic Variations Predict Brain Response to Faces

Erin W. Dickie, Amir Tahmasebi, Leon French, Natasa Kovacevic, Tobias Banaschewski, Gareth J. Barker, Arun Bokde, Christian Büchel, Patricia Conrod, Herta Flor, Hugh Garavan, Juergen Gallinat, Penny Gowland, Andreas Heinz, Bernd Ittermann, Claire Lawrence, Karl Mann, Jean-Luc Martinot, Frauke Nees, Thomas Nichols, Mark Lathrop, Eva Loth, Zdenka Pausova, Marcela Rietschel, Michal N. Smolka, Andreas Ströhle, Roberto Toro, Gunter Schumann, the IMAGEN consortium, Tomáš Paus

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