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The illustration expresses that inhibitory neurons exert a higher level of control to the comparatively large number of excitatory neurons in the neocortex with the metaphor of babysitting many playing babies. The neurons can be largely categorized into excitatory and inhibitory. Exactly how the two interact in order to maintain balance of the brain is a fundamental question in neurobiology. The results demonstrated that not only is it the higher firing rate of inhibitory neurons that keep things in check, but it is also where these neurons are positioned to influence and control other neurons. Kajiwara et al. (2021)
Image Credit: Science Manga Studio (parsely918, noguchi.m, and Hayanon. 2021)