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Table of Contents

May 2021

Overview of cell nuclei in a pluripotent zebrafish embryo, illustrating the variety of patterns formed by DNA in different cells. These patterns were mapped to multiplicative cascades, capturing DNA distribution across length scales. This mapping also relates the DNA distribution in these cells to a wider class of multi-fractal systems, including, for example, clouds in the sky or cracks in the soil. The image shows an optical section through a sphere stage embryo acquired by STimulated Emission Depletion (STED) microscopy, field of view 155-by-155 micrometers.

Image Credit: Amra Noa Lennart Hilbert, Karlsruhe Institute of Technology, Institute of Biological and Chemical System; image acquired at Karlsruhe Center for Optics and Photonics; 2021

Editorials

Ten simple rules to cultivate transdisciplinary collaboration in data science

Faryad Sahneh, Meghan A. Balk, Marina Kisley, Chi-kwan Chan, Mercury Fox, Brian Nord, Eric Lyons, Tyson Swetnam, Daniela Huppenkothen, Will Sutherland, Ramona L. Walls, Daven P. Quinn, Tonantzin Tarin, David LeBauer, David Ribes, Dunbar P. Birnie III, Carol Lushbough, Eric Carr, Grey Nearing, Jeremy Fischer, Kevin Tyle, Luis Carrasco, Meagan Lang, Peter W. Rose, Richard R. Rushforth, Samapriya Roy, Thomas Matheson, Tina Lee, C. Titus Brown, Tracy K. Teal, Monica Papeș, Stephen Kobourov, Nirav Merchant

Ten simple rules to make your publication look better

Friederike Ehrhart, Chris T. Evelo

Ten simple rules for productive lab meetings

Nigel Golden, Kadambari Devarajan, Cathleen Balantic, Joseph Drake, Michael T. Hallworth, Toni Lyn Morelli

Education Articles

Ten steps to investigate a cellular system with mathematical modeling

Jasia King, Kerbaï Saïd Eroumé, Roman Truckenmüller, Stefan Giselbrecht, Ann E. Cowan, Leslie Loew, Aurélie Carlier

Fostering accessible online education using Galaxy as an e-learning platform

Beatriz Serrano-Solano, Melanie C. Föll, Cristóbal Gallardo-Alba, Anika Erxleben, Helena Rasche, Saskia Hiltemann, Matthias Fahrner, Mark J. Dunning, Marcel H. Schulz, Beáta Scholtz, Dave Clements, Anton Nekrutenko, Bérénice Batut, Björn A. Grüning

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Can molecular dynamics simulations improve the structural accuracy and virtual screening performance of GPCR models?

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MiMeNet: Exploring microbiome-metabolome relationships using neural networks

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