October 2021

The elucidation of the transcriptional regulatory networks that orchestrate brain development is an important problem in systems biology. Biologists have performed reliable low-throughput investigations of regulatory interactions between transcription factors and target genes for decades, providing a deep source of information that is not fully exploited. Chu et al. reviewed over 3,000 research publications to document low-throughput experimental evidence for 1,499 unique regulatory interactions shown in the figure, involving 251 transcription factors (blue) and 825 targets (orange). Article

Image Credit: The network graphic was created by Eric Ching-Pan Chu (first author) using Cytoscape (Shannon et al., Genome Res 2003).

Editorials

Ten simple rules for switching from face-to-face to remote conference: An opportunity to estimate the reduction in GHG emissions

Valentin Guignon, Catherine Breton, Jérôme Mariette, François Sabot, Julien Fumey, Vincent Lefort, Anna-Sophie Fiston-Lavier

PLOS Computational Biology: published October 18, 2021 | https://doi.org/10.1371/journal.pcbi.1009321

Ten simple rules for training yourself in an emerging field

Whitney M. Woelmer, L. M. Bradley, Lisa T. Haber, David H. Klinges, Abigail S. L. Lewis, Elizabeth J. Mohr, Christa L. Torrens, Kathryn I. Wheeler, Alyssa M. Willson

PLOS Computational Biology: published October 28, 2021 | https://doi.org/10.1371/journal.pcbi.1009440

Education Articles

Bioinformatics in Sudan: Status and challenges case study: The National University-Sudan

Sofia B. Mohamed, Sumaya Kambal, Sabah A. E. Ibrahim, Esra Abdalwhab, Abdalla Munir, Arwa Ibrahim, Qurashi Mohamed Ali

PLOS Computational Biology: published October 21, 2021 | https://doi.org/10.1371/journal.pcbi.1009462

Crowdsourcing biocuration: The Community Assessment of Community Annotation with Ontologies (CACAO)

Jolene Ramsey, Brenley McIntosh, Daniel Renfro, Suzanne A. Aleksander, Sandra LaBonte, Curtis Ross, Adrienne E. Zweifel, Nathan Liles, Shabnam Farrar, Jason J. Gill, Ivan Erill, Sarah Ades, Tanya Z. Berardini, Jennifer A. Bennett, Siobhan Brady, Robert Britton, Seth Carbon, Steven M. Caruso, Dave Clements, Ritu Dalia, Meredith Defelice, Erin L. Doyle, Iddo Friedberg, Susan M. R. Gurney, Lee Hughes, Allison Johnson, Jason M. Kowalski, Donghui Li, Ruth C. Lovering, Tamara L. Mans, Fiona McCarthy, Sean D. Moore, Rebecca Murphy, Timothy D. Paustian, Sarah Perdue, Celeste N. Peterson, Birgit M. Prüß, Margaret S. Saha, Robert R. Sheehy, John T. Tansey, Louise Temple, Alexander William Thorman, Saul Trevino, Amy Cheng Vollmer, Virginia Walbot, Joanne Willey, Deborah A. Siegele, James C. Hu

PLOS Computational Biology: published October 28, 2021 | https://doi.org/10.1371/journal.pcbi.1009463

Review

Segmentation and genome annotation algorithms for identifying chromatin state and other genomic patterns

Maxwell W. Libbrecht, Rachel C. W. Chan, Michael M. Hoffman

PLOS Computational Biology: published October 14, 2021 | https://doi.org/10.1371/journal.pcbi.1009423

Research Articles

Action planning and control under uncertainty emerge through a desirability-driven competition between parallel encoding motor plans

Vince Enachescu, Paul Schrater, Stefan Schaal, Vassilios Christopoulos

PLOS Computational Biology: published October 1, 2021 | https://doi.org/10.1371/journal.pcbi.1009429

Memory shapes microbial populations

Chaitanya S. Gokhale, Stefano Giaimo, Philippe Remigi

PLOS Computational Biology: published October 1, 2021 | https://doi.org/10.1371/journal.pcbi.1009431

Separable actions of acetylcholine and noradrenaline on neuronal ensemble formation in hippocampal CA3 circuits

Luke Y. Prince, Travis Bacon, Rachel Humphries, Krasimira Tsaneva-Atanasova, Claudia Clopath, Jack R. Mellor

PLOS Computational Biology: published October 1, 2021 | https://doi.org/10.1371/journal.pcbi.1009435

Regulation of transcription reactivation dynamics exiting mitosis

Sergio Sarnataro, Andrea Riba, Nacho Molina

PLOS Computational Biology: published October 4, 2021 | https://doi.org/10.1371/journal.pcbi.1009354

Choice history effects in mice and humans improve reward harvesting efficiency

Junior Samuel López-Yépez, Juliane Martin, Oliver Hulme, Duda Kvitsiani

PLOS Computational Biology: published October 4, 2021 | https://doi.org/10.1371/journal.pcbi.1009452

The importance of urgency in decision making based on dynamic information

Lorenzo Ferrucci, Aldo Genovesio, Encarni Marcos

PLOS Computational Biology: published October 4, 2021 | https://doi.org/10.1371/journal.pcbi.1009455

Analysis of 11,430 recombinant protein production experiments reveals that protein yield is tunable by synonymous codon changes of translation initiation sites

Bikash K. Bhandari, Chun Shen Lim, Daniela M. Remus, Augustine Chen, Craig van Dolleweerd, Paul P. Gardner

PLOS Computational Biology: published October 5, 2021 | https://doi.org/10.1371/journal.pcbi.1009461

DeepCellState: An autoencoder-based framework for predicting cell type specific transcriptional states induced by drug treatment

Ramzan Umarov, Yu Li, Erik Arner

PLOS Computational Biology: published October 5, 2021 | https://doi.org/10.1371/journal.pcbi.1009465

Recursive MAGUS: Scalable and accurate multiple sequence alignment

Vladimir Smirnov

PLOS Computational Biology: published October 6, 2021 | https://doi.org/10.1371/journal.pcbi.1008950

Grey-box modeling and hypothesis testing of functional near-infrared spectroscopy-based cerebrovascular reactivity to anodal high-definition tDCS in healthy humans

Yashika Arora, Pushpinder Walia, Mitsuhiro Hayashibe, Makii Muthalib, Shubhajit Roy Chowdhury, Stephane Perrey, Anirban Dutta

PLOS Computational Biology: published October 6, 2021 | https://doi.org/10.1371/journal.pcbi.1009386

Sarc-Graph: Automated segmentation, tracking, and analysis of sarcomeres in hiPSC-derived cardiomyocytes

Bill Zhao, Kehan Zhang, Christopher S. Chen, Emma Lejeune

PLOS Computational Biology: published October 6, 2021 | https://doi.org/10.1371/journal.pcbi.1009443

Molecular mechanism of proton-coupled ligand translocation by the bacterial efflux pump EmrE

Jakub Jurasz, Maciej Bagiński, Jacek Czub, Miłosz Wieczór

PLOS Computational Biology: published October 6, 2021 | https://doi.org/10.1371/journal.pcbi.1009454

A metric for evaluating biological information in gene sets and its application to identify co-expressed gene clusters in PBMC

Jason Bennett, Mikhail Pomaznoy, Akul Singhania, Bjoern Peters

PLOS Computational Biology: published October 6, 2021 | https://doi.org/10.1371/journal.pcbi.1009459

Comprehensive analysis of lectin-glycan interactions reveals determinants of lectin specificity

Daniel E. Mattox, Chris Bailey-Kellogg

PLOS Computational Biology: published October 6, 2021 | https://doi.org/10.1371/journal.pcbi.1009470

Narrative event segmentation in the cortical reservoir

Peter Ford Dominey

PLOS Computational Biology: published October 7, 2021 | https://doi.org/10.1371/journal.pcbi.1008993

Paranoia, self-deception and overconfidence

Rosa A. Rossi-Goldthorpe, Yuan Chang Leong, Pantelis Leptourgos, Philip R. Corlett

PLOS Computational Biology: published October 7, 2021 | https://doi.org/10.1371/journal.pcbi.1009453

Tracking calcium dynamics from individual neurons in behaving animals

Thibault Lagache, Alison Hanson, Jesús E. Pérez-Ortega, Adrienne Fairhall, Rafael Yuste

PLOS Computational Biology: published October 8, 2021 | https://doi.org/10.1371/journal.pcbi.1009432

Segmentation-Less, Automated, Vascular Vectorization

Samuel A. Mihelic, William A. Sikora, Ahmed M. Hassan, Michael R. Williamson, Theresa A. Jones, Andrew K. Dunn

PLOS Computational Biology: published October 8, 2021 | https://doi.org/10.1371/journal.pcbi.1009451

Engineering gene overlaps to sustain genetic constructs in vivo

Antoine L. Decrulle, Antoine Frénoy, Thomas A. Meiller-Legrand, Aude Bernheim, Chantal Lotton, Arnaud Gutierrez, Ariel B. Lindner

PLOS Computational Biology: published October 8, 2021 | https://doi.org/10.1371/journal.pcbi.1009475

Pulsed low-energy stimulation initiates electric turbulence in cardiac tissue

Rupamanjari Majumder, Sayedeh Hussaini, Vladimir S. Zykov, Stefan Luther, Eberhard Bodenschatz

PLOS Computational Biology: published October 8, 2021 | https://doi.org/10.1371/journal.pcbi.1009476

qc3C: Reference-free quality control for Hi-C sequencing data

Matthew Z. DeMaere, Aaron E. Darling

PLOS Computational Biology: published October 11, 2021 | https://doi.org/10.1371/journal.pcbi.1008839

Enhancing breakpoint resolution with deep segmentation model: A general refinement method for read-depth based structural variant callers

Yao-zhong Zhang, Seiya Imoto, Satoru Miyano, Rui Yamaguchi

PLOS Computational Biology: published October 11, 2021 | https://doi.org/10.1371/journal.pcbi.1009186

Improved prediction of smoking status via isoform-aware RNA-seq deep learning models

Zifeng Wang, Aria Masoomi, Zhonghui Xu, Adel Boueiz, Sool Lee, Tingting Zhao, Russell Bowler, Michael Cho, Edwin K. Silverman, Craig Hersh, Jennifer Dy, Peter J. Castaldi

PLOS Computational Biology: published October 11, 2021 | https://doi.org/10.1371/journal.pcbi.1009433

The information theory of developmental pruning: Optimizing global network architectures using local synaptic rules

Carolin Scholl, Michael E. Rule, Matthias H. Hennig

PLOS Computational Biology: published October 11, 2021 | https://doi.org/10.1371/journal.pcbi.1009458

Frank-Starling mechanism, fluid responsiveness, and length-dependent activation: Unravelling the multiscale behaviors with an in silico analysis

Sarah Kosta, Pierre C. Dauby

PLOS Computational Biology: published October 11, 2021 | https://doi.org/10.1371/journal.pcbi.1009469

Cortical feedback and gating in odor discrimination and generalization

Gaia Tavoni, David E. Chen Kersen, Vijay Balasubramanian

PLOS Computational Biology: published October 11, 2021 | https://doi.org/10.1371/journal.pcbi.1009479

Steady-state measures of visual suppression

Daniel H. Baker, Greta Vilidaite, Alex R. Wade

PLOS Computational Biology: published October 13, 2021 | https://doi.org/10.1371/journal.pcbi.1009507

Modular assembly of dynamic models in systems biology

Michael Pan, Peter J. Gawthrop, Joseph Cursons, Edmund J. Crampin

PLOS Computational Biology: published October 13, 2021 | https://doi.org/10.1371/journal.pcbi.1009513

Interplay between mobility, multi-seeding and lockdowns shapes COVID-19 local impact

Mattia Mazzoli, Emanuele Pepe, David Mateo, Ciro Cattuto, Laetitia Gauvin, Paolo Bajardi, Michele Tizzoni, Alberto Hernando, Sandro Meloni, José J. Ramasco

PLOS Computational Biology: published October 14, 2021 | https://doi.org/10.1371/journal.pcbi.1009326

Universal risk phenotype of US counties for flu-like transmission to improve county-specific COVID-19 incidence forecasts

Yi Huang, Ishanu Chattopadhyay

PLOS Computational Biology: published October 14, 2021 | https://doi.org/10.1371/journal.pcbi.1009363

Dynamics and turnover of memory CD8 T cell responses following yellow fever vaccination

Veronika I. Zarnitsyna, Rama S. Akondy, Hasan Ahmed, Donald J. McGuire, Vladimir G. Zarnitsyn, Mia Moore, Philip L. F. Johnson, Rafi Ahmed, Kelvin W. Li, Marc K. Hellerstein, Rustom Antia

PLOS Computational Biology: published October 14, 2021 | https://doi.org/10.1371/journal.pcbi.1009468

Slipknotted and unknotted monovalent cation-proton antiporters evolved from a common ancestor

Vasilina Zayats, Agata P. Perlinska, Aleksandra I. Jarmolinska, Borys Jastrzebski, Stanislaw Dunin-Horkawicz, Joanna I. Sulkowska

PLOS Computational Biology: published October 14, 2021 | https://doi.org/10.1371/journal.pcbi.1009502

Visual perception of texture regularity: Conjoint measurements and a wavelet response-distribution model

Hua-Chun Sun, David St-Amand, Curtis L. Baker Jr., Frederick A. A. Kingdom

PLOS Computational Biology: published October 15, 2021 | https://doi.org/10.1371/journal.pcbi.1008802

State transitions through inhibitory interneurons in a cortical network model

Alexander Bryson, Samuel F. Berkovic, Steven Petrou, David B. Grayden

PLOS Computational Biology: published October 15, 2021 | https://doi.org/10.1371/journal.pcbi.1009521

Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma

Davis T. Weaver, Kathleen I. Pishas, Drew Williamson, Jessica Scarborough, Stephen L. Lessnick, Andrew Dhawan, Jacob G. Scott

PLOS Computational Biology: published October 18, 2021 | https://doi.org/10.1371/journal.pcbi.1008755

Universally valid reduction of multiscale stochastic biochemical systems using simple non-elementary propensities

Yun Min Song, Hyukpyo Hong, Jae Kyoung Kim

PLOS Computational Biology: published October 18, 2021 | https://doi.org/10.1371/journal.pcbi.1008952

Factors affecting aerosol SARS-CoV-2 transmission via HVAC systems; a modeling study

Zachary J. Cotman, Michael J. Bowden, Barrett P. Richter, Joseph H. Phelps, Christopher J. Dibble

PLOS Computational Biology: published October 18, 2021 | https://doi.org/10.1371/journal.pcbi.1009474

Time to revisit the endpoint dilution assay and to replace the TCID₅₀ as a measure of a virus sample’s infection concentration

Daniel Cresta, Donald C. Warren, Christian Quirouette, Amanda P. Smith, Lindey C. Lane, Amber M. Smith, Catherine A. A. Beauchemin

PLOS Computational Biology: published October 18, 2021 | https://doi.org/10.1371/journal.pcbi.1009480

Discrete mechanical model of lamellipodial actin network implements molecular clutch mechanism and generates arcs and microspikes

David M. Rutkowski, Dimitrios Vavylonis

PLOS Computational Biology: published October 18, 2021 | https://doi.org/10.1371/journal.pcbi.1009506

RgCop-A regularized copula based method for gene selection in single-cell RNA-seq data

Snehalika Lall, Sumanta Ray, Sanghamitra Bandyopadhyay

PLOS Computational Biology: published October 19, 2021 | https://doi.org/10.1371/journal.pcbi.1009464

Experiment level curation of transcriptional regulatory interactions in neurodevelopment

Eric Ching-Pan Chu, Alexander Morin, Tak Hou Calvin Chang, Tue Nguyen, Yi-Cheng Tsai, Aman Sharma, Chao Chun Liu, Paul Pavlidis

PLOS Computational Biology: published October 19, 2021 | https://doi.org/10.1371/journal.pcbi.1009484

pyActigraphy: Open-source python package for actigraphy data visualization and analysis

Grégory Hammad, Mathilde Reyt, Nikita Beliy, Marion Baillet, Michele Deantoni, Alexia Lesoinne, Vincenzo Muto, Christina Schmidt

PLOS Computational Biology: published October 19, 2021 | https://doi.org/10.1371/journal.pcbi.1009514

Estimating ectopic beat probability with simplified statistical models that account for experimental uncertainty

Qingchu Jin, Joseph L. Greenstein, Raimond L. Winslow

PLOS Computational Biology: published October 19, 2021 | https://doi.org/10.1371/journal.pcbi.1009536

A data-driven approach for constructing mutation categories for mutational signature analysis

Gal Gilad, Mark D. M. Leiserson, Roded Sharan

PLOS Computational Biology: published October 19, 2021 | https://doi.org/10.1371/journal.pcbi.1009542

Extended graphical lasso for multiple interaction networks for high dimensional omics data

Yang Xu, Hongmei Jiang, Wenxin Jiang

PLOS Computational Biology: published October 20, 2021 | https://doi.org/10.1371/journal.pcbi.1008794

Atorvastatin-mediated rescue of cancer-related cognitive changes in combined anticancer therapies

Junho Lee, Jin Su Kim, Yangjin Kim

PLOS Computational Biology: published October 20, 2021 | https://doi.org/10.1371/journal.pcbi.1009457

How conformity can lead to polarised social behaviour

Folco Panizza, Alexander Vostroknutov, Giorgio Coricelli

PLOS Computational Biology: published October 20, 2021 | https://doi.org/10.1371/journal.pcbi.1009530

Comprehensive discovery of CRISPR-targeted terminally redundant sequences in the human gut metagenome: Viruses, plasmids, and more

Ryota Sugimoto, Luca Nishimura, Phuong Thanh Nguyen, Jumpei Ito, Nicholas F. Parrish, Hiroshi Mori, Ken Kurokawa, Hirofumi Nakaoka, Ituro Inoue

PLOS Computational Biology: published October 21, 2021 | https://doi.org/10.1371/journal.pcbi.1009428

Estimation of regional polygenicity from GWAS provides insights into the genetic architecture of complex traits

Ruth Johnson, Kathryn S. Burch, Kangcheng Hou, Mario Paciuc, Bogdan Pasaniuc, Sriram Sankararaman

PLOS Computational Biology: published October 21, 2021 | https://doi.org/10.1371/journal.pcbi.1009483

Better tired than lost: Turtle ant trail networks favor coherence over short edges

Arjun Chandrasekhar, James A. R. Marshall, Cortnea Austin, Saket Navlakha, Deborah M. Gordon

PLOS Computational Biology: published October 21, 2021 | https://doi.org/10.1371/journal.pcbi.1009523

PaIRKAT: A pathway integrated regression-based kernel association test with applications to metabolomics and COPD phenotypes

Charlie M. Carpenter, Weiming Zhang, Lucas Gillenwater, Cameron Severn, Tusharkanti Ghosh, Russell Bowler, Katerina Kechris, Debashis Ghosh

PLOS Computational Biology: published October 22, 2021 | https://doi.org/10.1371/journal.pcbi.1008986

CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation

Tariq Daouda, Maude Dumont-Lagacé, Albert Feghaly, Yahya Benslimane, Rébecca Panes, Mathieu Courcelles, Mohamed Benhammadi, Lea Harrington, Pierre Thibault, François Major, Yoshua Bengio, Étienne Gagnon, Sébastien Lemieux, Claude Perreault

PLOS Computational Biology: published October 22, 2021 | https://doi.org/10.1371/journal.pcbi.1009482

Multicellular spatial model of RNA virus replication and interferon responses reveals factors controlling plaque growth dynamics

Josua O. Aponte-Serrano, Jordan J. A. Weaver, T. J. Sego, James A. Glazier, Jason E. Shoemaker

PLOS Computational Biology: published October 25, 2021 | https://doi.org/10.1371/journal.pcbi.1008874

Building and experimenting with an agent-based model to study the population-level impact of CommunityRx, a clinic-based community resource referral intervention

Stacy Tessler Lindau, Jennifer A. Makelarski, Chaitanya Kaligotla, Emily M. Abramsohn, David G. Beiser, Chiahung Chou, Nicholson Collier, Elbert S. Huang, Charles M. Macal, Jonathan Ozik, Elizabeth L. Tung

PLOS Computational Biology: published October 25, 2021 | https://doi.org/10.1371/journal.pcbi.1009471

OutbreakFlow: Model-based Bayesian inference of disease outbreak dynamics with invertible neural networks and its application to the COVID-19 pandemics in Germany

Stefan T. Radev, Frederik Graw, Simiao Chen, Nico T. Mutters, Vanessa M. Eichel, Till Bärnighausen, Ullrich Köthe

PLOS Computational Biology: published October 25, 2021 | https://doi.org/10.1371/journal.pcbi.1009472

NanoMethViz: An R/Bioconductor package for visualizing long-read methylation data

Shian Su, Quentin Gouil, Marnie E. Blewitt, Dianne Cook, Peter F. Hickey, Matthew E. Ritchie

PLOS Computational Biology: published October 25, 2021 | https://doi.org/10.1371/journal.pcbi.1009524

Complexity and diversity in sparse code priors improve receptive field characterization of Macaque V1 neurons

Ziniu Wu, Harold Rockwell, Yimeng Zhang, Shiming Tang, Tai Sing Lee

PLOS Computational Biology: published October 25, 2021 | https://doi.org/10.1371/journal.pcbi.1009528

Using ephaptic coupling to estimate the synaptic cleft resistivity of the calyx of Held synapse

Martijn C. Sierksma, J. Gerard G. Borst

PLOS Computational Biology: published October 26, 2021 | https://doi.org/10.1371/journal.pcbi.1009527

Assessing the drivers of syphilis among men who have sex with men in Switzerland reveals a key impact of screening frequency: A modelling study

Suraj Balakrishna, Luisa Salazar-Vizcaya, Axel J. Schmidt, Viacheslav Kachalov, Katharina Kusejko, Maria Christine Thurnheer, Jan A. Roth, Dunja Nicca, Matthias Cavassini, Manuel Battegay, Patrick Schmid, Enos Bernasconi, Huldrych F. Günthard, Andri Rauch, Roger D. Kouyos, the Swiss HIV Cohort Study (SHCS)

PLOS Computational Biology: published October 26, 2021 | https://doi.org/10.1371/journal.pcbi.1009529

Evidence from simulation studies for selective constraints on the codon usage of the Angiosperm psbA gene

Antonina Kalkus, Joy Barrett, Theyjasvi Ashok, Brian R. Morton

PLOS Computational Biology: published October 26, 2021 | https://doi.org/10.1371/journal.pcbi.1009535

Spatial heterogeneity enhance robustness of large multi-species ecosystems

Susanne Pettersson, Martin Nilsson Jacobi

PLOS Computational Biology: published October 27, 2021 | https://doi.org/10.1371/journal.pcbi.1008899

Determining travel fluxes in epidemic areas

Daipeng Chen, Yuyi Xue, Yanni Xiao

PLOS Computational Biology: published October 27, 2021 | https://doi.org/10.1371/journal.pcbi.1009473

The network structure affects the fixation probability when it couples to the birth-death dynamics in finite population

Mohammad Ali Dehghani, Amir Hossein Darooneh, Mohammad Kohandel

PLOS Computational Biology: published October 27, 2021 | https://doi.org/10.1371/journal.pcbi.1009537

Operational response simulation tool for epidemics within refugee and IDP settlements: A scenario-based case study of the Cox’s Bazar settlement

Joseph Aylett-Bullock, Carolina Cuesta-Lazaro, Arnau Quera-Bofarull, Anjali Katta, Katherine Hoffmann Pham, Benjamin Hoover, Hendrik Strobelt, Rebeca Moreno Jimenez, Aidan Sedgewick, Egmond Samir Evers, David Kennedy, Sandra Harlass, Allen Gidraf Kahindo Maina, Ahmad Hussien, Miguel Luengo-Oroz

PLOS Computational Biology: published October 28, 2021 | https://doi.org/10.1371/journal.pcbi.1009360

Correction

Correction: CTD: An information-theoretic algorithm to interpret sets of metabolomic and transcriptomic perturbations in the context of graphical models

Lillian R. Thistlethwaite, Varduhi Petrosyan, Xiqi Li, Marcus J. Miller, Sarah H. Elsea, Aleksandar Milosavljevic

PLOS Computational Biology: published October 25, 2021 | https://doi.org/10.1371/journal.pcbi.1009551

Formal Comments

On testing structural identifiability by a simple scaling method: Relying on scaling symmetries can be misleading

Alejandro F. Villaverde, Gemma Massonis

PLOS Computational Biology: published October 14, 2021 | https://doi.org/10.1371/journal.pcbi.1009032

The limitations, dangers, and benefits of simple methods for testing identifiability

Mario Castro, Rob J. de Boer

PLOS Computational Biology: published October 14, 2021 | https://doi.org/10.1371/journal.pcbi.1009425

Cover

An experimentally validated regulatory network involving neurodevelopmental genes.

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