Table of Contents

February 2006

Shown here are the probabilities that a genus was alive at a fossil site, obtained from a dataset of fossil occurrences by Markov chain Monte Carlo method. The dataset consists of 139 genera of large land mammals (horizontal axis) and 124 fossil sites from the European late Cenozoic (vertical axis). The sites have been ordered by one of their most likely temporal sequences, with the oldest site at the bottom (see Puolamäki et al).

Image Credit: Image by K. Puolamäki, created with GNU R software


Ten Simple Rules for Getting Grants

Philip E Bourne, Leo M Chalupa

Message from ISCB

ISMB 2006

Goran Neshich, Philip E Bourne, Søren Brunak

Research Articles

Seriation in Paleontological Data Using Markov Chain Monte Carlo Methods

Kai Puolamäki, Mikael Fortelius, Heikki Mannila

Traditional Biomolecular Structure Determination by NMR Spectroscopy Allows for Major Errors

Sander B Nabuurs, Chris A. E. M Spronk, Geerten W Vuister, Gert Vriend

Dependency Map of Proteins in the Small Ribosomal Subunit

Kay Hamacher, Joanna Trylska, J. Andrew McCammon

The Fragile Breakage versus Random Breakage Models of Chromosome Evolution

Qian Peng, Pavel A Pevzner, Glenn Tesler


Correction: Time to Organize the Bioinformatics Resourceome

Nicola Cannata, Emanuela Merelli, Russ B Altman

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