Table of Contents

June 2008

The tabular background is values for human Y chromosome microsatellite repeats with the predicted haplogroup for a sample highlighted with a dashed yellow oval. The evolutionary history of the haplogroup is traced in red on the human Y chromosome gene tree; haplogroups traversed during the prediction process and corresponding confidence values are displayed in grey in the lower section of the montage (see Schlecht et al., doi:10.1371/journal.pcbi.1000093).

Image Credit: Nirav Merchant


Ten Simple Rules for Organizing a Scientific Meeting

Manuel Corpas, Nils Gehlenborg, Sarath Chandra Janga, Philip E. Bourne

How To Advance Open International Scientific Exchange

Barbara Bryant

Message from ISCB

ISMB 2008 Toronto

Michal Linial, Jill P. Mesirov, B. J. Morrison McKay, Burkhard Rost

Research Articles

A Comparative Computer Simulation of Dendritic Morphology

Duncan E. Donohue, Giorgio A. Ascoli

CSMET: Comparative Genomic Motif Detection via Multi-Resolution Phylogenetic Shadowing

Pradipta Ray, Suyash Shringarpure, Mladen Kolar, Eric P. Xing

Machine-Learning Approaches for Classifying Haplogroup from Y Chromosome STR Data

Joseph Schlecht, Matthew E. Kaplan, Kobus Barnard, Tatiana Karafet, Michael F. Hammer, Nirav C. Merchant

Dynamics and Potential Impact of the Immune Response to Chronic Myelogenous Leukemia

Peter S. Kim, Peter P. Lee, Doron Levy

Model-Based Hypothesis Testing of Key Mechanisms in Initial Phase of Insulin Signaling

Gunnar Cedersund, Jacob Roll, Erik Ulfhielm, Anna Danielsson, Henrik Tidefelt, Peter Strålfors

How To Record a Million Synaptic Weights in a Hippocampal Slice

Upinder S. Bhalla

Network Analysis of Intrinsic Functional Brain Connectivity in Alzheimer's Disease

Kaustubh Supekar, Vinod Menon, Daniel Rubin, Mark Musen, Michael D. Greicius