Table of Contents

January 2015

The image represents a signal in a three-dimensional NMR spectrum being assigned to a specific nucleus of the protein backbone. The multi-platform software COMPASS, as presented by Niklasson et al., was developed for this purpose. COMPASS was designed to be suitable for resonance assignments of small-to-large proteins from complete or limited data sets. User friendliness was also a priority when designing the software. Advantages over competing software include increased user control of the entire backbone assignment process and instant feedback on assignments in the form of a graphical representation of the calculated secondary structure.

Image Credit: Markus Niklasson


Ten Simple Rules for Organizing an Unconference

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Advancements and Challenges in Computational Biology

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Message from ISCB

ISCB Ebola Award for Important Future Research on the Computational Biology of Ebola Virus

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