Top: observed distribution of auxin transporters (PIN proteins) in shoot apical meristem cells of Arabidopsis. The image was obtained by immunolabelling of the PIN1 auxin-carrier using confocal microscopy. Bottom left: Digitized version of the top image where the efflux carriers have been manually positioned. Bottom right: simulated distribution of efflux carriers (in red) emerging from a flux-based polarization hypothesis of auxin transport. This type of virtual experiment makes it possible to test in silico different hypotheses on mechanisms that are not fully accessible experimentally and to assess their plausibility by comparing predictions with experimental data (see Stoma et al., doi:10.1371/journal.pcbi.1000207).
Image Credit: Szymon Stoma (INRIA, Virtual Plants project team), Christophe Godin (INRIA, Virtual Plants project team), Jan Traas (ENS-Lyon, RDP)
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