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PLOS Collections are important thematic issues or group projects of a variety of research outputs that need publishing and promotion. PLOS Computational Biology collaborates with other PLOS journals to expose the research to thousands of relevant researchers and give their high profile projects the visibility they deserve.

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PLOS Computational Biology: Topic Pages

This collection aims to increase the coverage of computational biology and genetics-related topics in Wikipedia by rewarding authors with a citable, PubMed-indexed static version of the living document on Wikipedia.

PLOS Computational Biology: Benchmarking

In this collection we gather the research articles published in the PLOS Computational Biology Benchmarking section that will help readers decide between a number of methods which are developed to solve scientific problems.

PLOS Computational Biology: Methods

The Methods Section was launched in 2013 and has given computational method development a dedicated space in the journal.

PLOS Computational Biology: Focus Features

PLOS Computational Biology "Focus Features" are a resource to encourage community engagement and discussion on a focussed topic.

Macromolecular Structure and Dynamics

The latest advancements in computational treatments of macromolecules focusing upon recent computational methods investigating various aspects of the relationship between macromolecular structure, dynamics, and function

PLOS Computational Biology 10th Anniversary

A PLOS Computational Biology "Taster" highlighting each section of the wide ranging articles published in the journal.

Stories from the Road: ISCB Student Council Collection

For the past 10 years the International Society for Computational Biology (ISCB) Student Council has provided events and activities to help support and encourage young budding scientists. This article series, written by past and present student council members, shares some of the trials and tribulations of the ISCB student community.

About My Lab

'About My Lab' was launched with the mission to share knowledge about lab organization and scientific management. Each Perspective represents an interview with a Principal Investigator, who shares his or her experience of running a lab by discussing selected topics in an informal and personal style.

Translational Bioinformatics

'Translational Bioinformatics' is a collection of PLOS Computational Biology Education articles which reads as a "book" to be used as a reference or tutorial for a graduate level introductory course on the science of translational bioinformatics.


The PLOS Computational Biology Software Section was launched in 2011 and has been steadily gathering momentum since its beginnings. Handled by our Software Editors, Software articles highlight and describe outstanding open source software of exceptional importance that has been shown to provide new biological insights.

Bioinformatics: Starting Early

Bioinformatics is being introduced into the school curriculum earlier and earlier as the field matures. “Bioinformatics: Starting Early” is devoted to teaching bioinformatics in secondary schools.

PLOS Computational Biology: Editors' Outlook

The PLOS Computational Biology Editors' Outlook collection provides diverse mini reviews from members of the Editorial Board on their research areas, and includes discussions of new and future developments.

The Roots of Bioinformatics

This collection of essays from prominent workers in the field of bioinformatics relates how selected scientific, technological, economic, and even cultural threads came to influence the development of the field we know today.

Conference Postcards

Conference Postcards are designed to vividly recount to those not at a conference what happened at the event that was scientifically noteworthy. Each article in this Collection is devoted to a single conference and the Postcards contained in each article are selected by PLOS editors.


The number and scope of scientific databases has soared in recent years, creating a new profession, the biocurator. These "museum catalogers of the Internet age" face a continuous struggle of making ever growing amounts of data accessible.

Core Facilities

These articles aim to explain how to set up and administrate Core Facilities, and the benefits to researchers and institutions of so doing.

Developing Computational Biology

A series of Perspective articles from computational biologists in a variety of countries, each of whom offers their personal viewpoint on the history, current status, and future of computational biology in their region.


Recognizing the need for training and education in bioinformatics and computational biology specifically targeted to biologists, PLOS Computational Biology launched its Education section in January 2006. The goals are to provide practical tutorials and background information on important computational methods.

RECOMB Regulatory Genomics and Systems Biology 2009

In a joint venture between PLOS Computational Biology, PLOS ONE and the conference program committee, this collection draws together papers from the 6th Annual RECOMB Satellite on Regulatory Genomics and the 5th Annual RECOMB Satellite onSystems Biology, held jointly at MIT, December 2-6, 2009

Ten Simple Rules

"Ten Simple Rules" provide a quick, concentrated guide for mastering some of the professional challenges research scientists face in their careers. 

Genomics of Emerging Infectious Disease

This collection of essays, perspectives, and reviews from six PLOS Journals provides insights into how genomics can revolutionize our understanding of emerging infectious disease.