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Table of Contents

March 2020

Many diseases are known to impede the deformability of the red blood cell, which may adversely impact the transport of red blood cells (red) and platelets (yellow) in flow. Czaja et al. observes with increasing fractions of stiffened red blood cells (purple) in flow, a decrease of platelet margination to the vessel wall. Specifically, this is observed as a decrease of a fluorescent platelet signal at the wall of a glass channel with flowing human whole blood, and confirmed via cell resolved simulations.

Image Credit: Benjamin Czaja, The University of Amsterdam

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