Table of Contents: April 2011

The rat vibrissal system provides an ideal model to examine how the physical embodiment of a sensory array shapes the sensing process. We quantified the morphology of the rat vibrissal array to develop a model that can be used to simulate the spatiotemporal patterns of vibrissa—object contact during tactile exploratory behavior (see Towal et al. doi:10.1371/journal.pcbi.1001120). The left half of the image illustrates the vibrissal array of a real rat, and the right half illustrates the model.

Image Credit: Brian Quist, Northwestern University


Minimum Information About a Simulation Experiment (MIASE)

Dagmar Waltemath, Richard Adams, Daniel A. Beard, Frank T. Bergmann, Upinder S. Bhalla, Randall Britten, Vijayalakshmi Chelliah, Michael T. Cooling, Jonathan Cooper, Edmund J. Crampin, Alan Garny, Stefan Hoops, Michael Hucka, Peter Hunter, Edda Klipp, Camille Laibe, Andrew K. Miller, Ion Moraru, David Nickerson, Poul Nielsen, Macha Nikolski, Sven Sahle, Herbert M. Sauro, Henning Schmidt, Jacky L. Snoep, Dominic Tolle, Olaf Wolkenhauer, Nicolas Le Novère


Research Articles

Quantifying the Relative Contributions of Divisive and Subtractive Feedback to Rhythm Generation

Joël Tabak, John Rinzel, Richard Bertram

Disentangling the Roles of Approach, Activation and Valence in Instrumental and Pavlovian Responding

Quentin J. M. Huys, Roshan Cools, Martin Gölzer, Eva Friedel, Andreas Heinz, Raymond J. Dolan, Peter Dayan

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  1. Correction: Disentangling the Roles of Approach, Activation and Valence in Instrumental and Pavlovian Responding

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The Morphology of the Rat Vibrissal Array: A Model for Quantifying Spatiotemporal Patterns of Whisker-Object Contact

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MDCK Cystogenesis Driven by Cell Stabilization within Computational Analogues

Jesse A. Engelberg, Anirban Datta, Keith E. Mostov, C. Anthony Hunt

A Mathematical Framework for Estimating Pathogen Transmission Fitness and Inoculum Size Using Data from a Competitive Mixtures Animal Model

James M. McCaw, Nimalan Arinaminpathy, Aeron C. Hurt, Jodie McVernon, Angela R. McLean