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Computational biology

Integrated computational analysis prioritizes candidate targets and pathways linking ochratoxin A exposure to hepatocellular carcinoma

Shili Yang, Huaiquan Liu, [ ... ], Bo Chen

A data-driven approach to hepatitis C forecasting using machine learning and epidemiological models

Abdul Mannan, Jamshaid Ul Rahman, Ebraheem Alzahrani, Osman Abubakar Fiidow

Computational identification and evaluation of Adenium obesum phytochemicals as potential EGFR inhibitors for targeted therapy against non-small-cell lung cancer

Md. Naziur Rahman, Abu Yousuf Hossin, [ ... ], Ajoy Kumer

Comparative machine learning models for predicting the compressive strength of ultra-high-performance concrete

Nguyen Thi Thu Nga, Nguyen Anh Tuan, Nguyen Tuan Tu, Huyen Thi Dang

Phycocyanobilin: A potential bioactive compound from Arthrospira platensis targeting LYN protein associated with systemic lupus erythematosus

Amnart Chaiprasert, Ping Han, Teeraphan Laomettachit, Marasri Ruengjitchatchawalya

An interpretable Hallmark pathway activity classifier for distinguishing CIN3/HSIL from invasive cervical squamous carcinoma: Development, external validation, and feature stability assessment

Mingyu Jia, Youyi Song, [ ... ], Mingzhu Ye

Machine Learning approaches for the detection of disease-causing variants in whole-genome data need to address the expression of functional genes

Camilla Mapstone, Julia Handl, David Talavera

Highly contiguous reference genome assembly of the endangered Orcés’ blue whiptail Holcosus orcesi

Gabriela Pozo, Diego F. Cisneros-Heredia, [ ... ], Maria de Lourdes Torres

Integrated transcriptomic profiling implicates MAPK14/p38α as a candidate shared molecular target at the sepsis–postoperative delirium interface with computational evidence for a losartan–MAPK14 association

Wei-Jia Kong, Jing-Xian Xue, [ ... ], Jiang-Tao Deng

Structural insights into the mosaic and modular organization of fourteen co-occurring resistance genes in multidrug resistant Enterobacteriaceae

Connor A. J. Rossel, Lieke B. van Alphen, Edou R. Heddema, Paul H. M. Savelkoul

Systems pharmacology reveals type I interferon and myeloid-like B cell reprogramming as candidate druggable axes in antiphospholipid syndrome

Bin Sun, Yiqiao Lu, Wei Liu, Chengze Wang

Revisiting differential expression analysis: An updated six-dimensional comparative study

Jianxiong Wu, Shaoke Lu, Hui Yao, Zhaoyuan Fang

Identification of candidate macrophage-ferroptosis crosstalk genes associated with immune infiltration in myocardial infarction: A bioinformatics analysis

Guoqin Wang, Zhulin Zhang, [ ... ], Shuang Guo

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