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Computational biology

Quantifying the diagnostic time gap in precision oncology: A retrospective analysis of potential time savings from same-day cartridge-based molecular testing versus next-generation sequencing in cytology specimens

Kevin Tran, Eveline Chen, W. Fraser Symmans, Gloria Hopkins Sura

Identification of SGK1 as a candidate regulator associated with myeloid cell senescence in ME/CFS: An integrative transcriptomic and experimental study

Yan Jin, Rui Qin, [ ... ], Xinghua Chen

Comprehensive Analysis of the AP2/ERF Transcription Factor Family in Schisandra chinensis and Its Implications for secondary metabolism

Kai Qian, Yifen Huang, [ ... ], Wei Nie

Gamma–distributed transmission memory in a reaction–diffusion epidemic model with nonlinear incidence

Martin Anokye, Luca Guerrini, [ ... ], Stefania Ragni

Personalized genomic landscape of prostate cancer in African American men reveals novel drivers and therapeutic opportunities

Shanta Murthy, Katie Fago, [ ... ], Mira Jung

Structure-based discovery of a novel Granzyme A (GZMA) inhibitor for autism spectrum disorder through integrative transcriptomics, virtual screening, and long-timescale molecular dynamics simulations

Metab Alharbi, Abdulrahman Alshammari, [ ... ], Talal Alshammari

Single-cell transcriptomics and machine learning characterize LTA4H-linked lipid metabolism and inflammatory signatures in the knee osteoarthritis IPFP/synovium compartment

Xin Chen, Shudong Li, [ ... ], Jifeng Zhao

Omicron SARS-CoV-2 shows NRP1-linked susceptibility in adipose-derived MSCs and alters primitive cord blood CD34⁺ HSPCs

Kanit Bhukhai, Nopmullee Tanhuad, [ ... ], Arunee Thitithanyanont

Integrated bioinformatics analysis identifies an immune-related gene signature associated with non-obstructive azoospermia

Yucheng Zhong, Songqing Ye, [ ... ], Xiaofu Qiu

Geospatial suitability of cacao in Amazonas (Peru): An ensemble predictive modeling approach (BIOMOD2) integrating multisource data, territorial management, and plant health

Jhon A. Zabaleta-Santisteban, Angel J. Medina-Medina, [ ... ], Elgar Barboza

Benchmarking ensemble and deep learning models for drought-responsive gene prioritisation in rice using multi-omics data

Kumanan N. Govaichelvan, Dharini Pathmanathan, Rabiatul Adawiah Zainal-Abidin, Arpah Abu

Intercellular GAS6-AXL signaling triggers podocyte cuproptosis in acute kidney injury upstream regulated by CEBPD

Jingmei Liang, Yuyun Hu, Bing Liao

A dual-functional antiviral and anticancer peptide to target intricate host-pathogen interacting proteins of human papillomavirus associated with head and neck cancer

Gayathri Ashok, Soumyadip Ghosh, [ ... ], Anand Anbarasu

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