Revising Your Manuscript
If you are submitting a revised manuscript, upload your revised submission to the submission system and include the following items:
Response to reviewers: Address the specific points made by each reviewer. Include your responses to all the reviewers’ and editors’ comments and list the changes you have made to the manuscript. Upload this as a “Response to reviewers” file.
Revised manuscript (marked-up copy): Include a marked-up copy of your manuscript file showing the changes you have made since the original submission. The best way to show these changes is the “Track Changes” option in Microsoft Word. Upload this as a "Revised Article with Changes Highlighted” file.
Revised manuscript (clean copy): Upload a clean copy of your revised manuscript that does not show your changes. Upload this as your “Manuscript” file.
How to submit your revised manuscript in Editorial Manager
Need more time to prepare your revision? Email email@example.com.
If you chose to post your manuscript on bioRxiv during PLOS initial submission, you may update or revise your preprint directly on bioRxiv at any time. Consult the bioRxiv submit page for specific instructions.