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Computational biology

Recurrent polyploidy and descending dysploidy as plant genome shapers: Insights from Sporobolus (Chloridoideae, Poaceae) genomes

Morgane Milin, Oscar Lima, Lin-Feng Li, Bo Li, Marc Beringer, Christian Parisod, Malika Ainouche, Armel Salmon

published 23 Feb 2026

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Sequencing of the invasive E. coli strain BEN2908 isolated from poultry: A comparative investigation of genomic regions shared with intestinal and extraintestinal model E. coli strains

Tobias Weber Martins, Angélina Trotereau, Simone Lahnig-Jacques, Maxime Branger, Sébastien Houle, Charles M. Dozois, Daniel Brisotto Pavanelo, Fabiana Horn, Catherine Schouler

published 23 Feb 2026

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Intraspecific identification of Actinidia eriantha Benth. based on chloroplast genes

Lan Lan, Jiale Mao, Bingyan Mao, Shuang Liu, Tao Li, Xiaohui Zhou, Houxing Lei, Songquan Wu, Jia Chen, Xiaoqin Zhang

published 23 Feb 2026

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Development of DHODH inhibitors incorporating virtual screening, pharmacophore modeling, fragment-based optimization methods, ADMET, molecular docking, molecular dynamics, PCA analysis, and free energy landscape

Qu Wang, Yu Hao Xu, Heng Jiang, Biao Deng, Zhu Liang

published 23 Feb 2026

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Effects of dietary glycyrrhiza polysaccharide on growth, serum biochemistry, and hepatic transcriptome in juvenile chinese sturgeon (Acipenser sinensis)

Jianming Zhang, Tian Tian, Rui He, Binzhong Wang, Wei Jiang, Yacheng Hu

published 23 Feb 2026

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Dissecting the shared genetic architecture of bipolar disorder, major depressive disorder, and attention-deficit hyperactivity disorder

Christopher Lawrence, Thomas Folkmann Hansen

published 23 Feb 2026

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Identification of two terpenoids from Withania coagulans with predicted multitarget binding affinity: An in vitro and in silico study

Hansa Gul, Nasir Assad, Zahida Nasreen, Nouman Ahmad, Yasir Assad, Muhammad Nauman Khan, Ahmed Vandy, Michael Lahai, Muhammad Naeem-ul-Hassan, Sezai Ercişli

published 20 Feb 2026

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The venom gland transcriptome of Tityus paraguayensis reveals a diverse array of bioactive molecules from the Brazilian Cerrado

Henrique Ranieri Covali-Pontes, Brayhan Meneguelli, Jéssica de Moraes Carretone, Alynne Coelho Ribeiro, Angélica Camargo dos Santos, Thais Fernanda Carlos, Marcos Roberto Chiaratti, Milene Ferro, Flávio Henrique Silva, Renata dos Santos Rodrigues, Malson Neilson Lucena

published 20 Feb 2026

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RWDisEnh+: Enhancing disease-enhancer association prediction through multiplex-heterogeneous networks

Duc-Hau Le

published 20 Feb 2026

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Alterations in the CTRB2 gene and response to chemotherapy in pancreatic cancer

Khalid Jazieh, Erin E. Carlson, Zafar Siddiqui, Katelyn E. Connelly, Jun Zhong, Jason W. Hoskins, Kari G. Rabe, MAYO-RGC Project Generation, Regeneron Genetics Center , Ann L. Oberg, Hugues Sicotte, Ryan M. Carr, Laufey T. Amundadottir, Samuel O. Antwi

published 19 Feb 2026

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Elucidating key targets and mechanisms of diethyl phthalate-induced colorectal cancer through network toxicology and molecular docking

Zijing Wang, Liyuan Ma, Zhanyuan Sun, Hengyi Lv, Ruxue Ma, Mengqi Ding, Hai Li, Tao Jiang

published 17 Feb 2026

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Identification of SORCS1 as a candidate gene associated with canine behavioral traits: Insights from guide dog training outcomes

Toshinori Omi, Chihiro Udagawa, Yuiko Kato, Shota Kawakami, Yumiko Uno, Kazuhiko Ochiai, Junzo Asano

published 17 Feb 2026

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96 sample parallel acoustic fragmentation for high throughput next generation sequencing library preparation

Marjan Mehrab-Mohseni, Kathlyne Jayne B. Bautista, Yusha Liu, Erika E. Maldonado-Rosado, Haofan Zheng, Matthew J. Niederhuber, Jonathan D. Rosen, Michell D. Carroll, Brian Velasco, James K. Tsuruta, Jinwook Kim, James S. Marron, Perry D. Haaland, Sandeep K. Kasoji, Piotr A. Mieczkowski, Austin J. Hepperla, Paul A. Dayton, Samantha G. Pattenden

published 17 Feb 2026

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