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Computational biology

In silico approaches to study the human asparagine synthetase: An insight of the interaction between the enzyme active sites and its substrates

Anam Riaz, Afshan Kaleem, Roheena Abdullah, Mehwish Iqtedar, Daniel C. Hoessli, Mahwish Aftab

published 02 Aug 2024

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Sedentary behavior from television watching elevates GlycA levels: A bidirectional Mendelian randomization study

Shuchuan Miao, Xiaoyan Wang, Lu Ma, Chao You

published 01 Aug 2024

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Large changes in detected selection signatures after a selection limit in mice bred for voluntary wheel-running behavior

David A. Hillis, Liran Yadgary, George M. Weinstock, Fernando Pardo-Manuel de Villena, Daniel Pomp, Theodore Garland Jr.

published 01 Aug 2024

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Comparative analysis of the liver transcriptome in the red-eared slider (Trachemys scripta elegans) post exposure to noise

Guangwei Ma, Ziye Zuo, Handong Li, Xiaofei Zhai, Tongliang Wang, Jichao Wang

published 01 Aug 2024

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A new type II CHH neuropeptide involves ovarian development in the peppermint shrimp, Lysmata vittata

Huiling Lan, Fang Liu, Li Lu, An Liu, Haihui Ye

published 01 Aug 2024

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Mechanistic insights into steroid hormone-mediated regulation of the androgen receptor gene

Andrew D. Gillen, Irene Hunter, Ekkehard Ullner, Iain J. McEwan

published 01 Aug 2024

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Addressing overlapping sample challenges in genome-wide association studies: Meta-reductive approach

Farid Rajabli, Azra Emekci

published 01 Aug 2024

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Causal relationship between gut microbiota and ankylosing spondylitis and potential mediating role of inflammatory cytokines: A mendelian randomization study

Xinyu Du, Haibo Li, Hongzhou Zhao, Shuangshuang Cui, Xiaozhuo Sun, Xiaochan Tan

published 31 Jul 2024

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DeepDate: A deep fusion model based on whale optimization and artificial neural network for Arabian date classification

Nour Eldeen Mahmoud Khalifa, Jiaji Wang, Mohamed Hamed N. Taha, Yudong Zhang

published 30 Jul 2024

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Structural modelling and preventive strategy targeting of WSSV hub proteins to combat viral infection in shrimp Penaeus monodon

Tanate Panrat, Amornrat Phongdara, Kitti Wuthisathid, Watcharachai Meemetta, Kornsunee Phiwsaiya, Rapeepun Vanichviriyakit, Saengchan Senapin, Pakkakul Sangsuriya

published 29 Jul 2024

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Reclassification of Botryococcus braunii chemical races into separate species based on a comparative genomics analysis

Devon J. Boland, Ivette Cornejo-Corona, Daniel R. Browne, Rebecca L. Murphy, John Mullet, Shigeru Okada, Timothy P. Devarenne

published 29 Jul 2024

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DeepDRA: Drug repurposing using multi-omics data integration with autoencoders

Taha Mohammadzadeh-Vardin, Amin Ghareyazi, Ali Gharizadeh, Karim Abbasi, Hamid R. Rabiee

published 26 Jul 2024

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Genome wide association study of clinical duration and age at onset of sporadic CJD

Holger Hummerich, Helen Speedy, Tracy Campbell, Lee Darwent, Elizabeth Hill, Steven Collins, Christiane Stehmann, Gabor G. Kovacs, Michael D. Geschwind, Karl Frontzek, Herbert Budka, Ellen Gelpi, Adriano Aguzzi, Sven J. van der Lee, Cornelia M. van Duijn, Pawel P. Liberski, Miguel Calero, Pascual Sanchez-Juan, Elodie Bouaziz-Amar, Jean-Louis Laplanche, Stéphane Haïk, Jean-Phillipe Brandel, Angela Mammana, Sabina Capellari, Anna Poleggi, Anna Ladogana, Maurizio Pocchiari, Saima Zafar, Stephanie Booth, Gerard H. Jansen, Aušrinė Areškevičiūtė, Eva Løbner Lund, Katie Glisic, Piero Parchi, Peter Hermann, Inga Zerr, Brian S. Appleby, Jiri Safar, Pierluigi Gambetti, John Collinge, Simon Mead

published 26 Jul 2024

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