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Cell signaling

Integrative proteomics reveals MSH6 to modulate PARP inhibitor sensitivity in BRCA1/2-proficient ovarian cancer

Ou Deng, Thales Da Costa Nepomuceno, [ ... ], Uwe Rix

Integrated transcriptomic profiling implicates MAPK14/p38α as a candidate shared molecular target at the sepsis–postoperative delirium interface with computational evidence for a losartan–MAPK14 association

Wei-Jia Kong, Jing-Xian Xue, [ ... ], Jiang-Tao Deng

Identification of candidate macrophage-ferroptosis crosstalk genes associated with immune infiltration in myocardial infarction: A bioinformatics analysis

Guoqin Wang, Zhulin Zhang, [ ... ], Shuang Guo

Separation-like irregularity and sample size optimism in high-discrimination logistic prediction models

Ye Liang, Louis Shuo Wang, Jiguang Yu, Xin Zan

Propranolol improves cognitive function and glymphatic system recovery through STAT3/MMP2 pathway after TBI

Dongming Gao, Guohui Huang, Lei Li, Peng Yu

A multimodal analysis suggests partial IRF8/TLR7-associated myeloid transcriptional convergence between diabetic kidney disease and Parkinson’s disease

Xue Hu, Yingzhuo Li, [ ... ], Jiaping Wang

Differential effects of ginsenosides on Ca²⁺ regulation in rotenone-treated neuronal and microglial cells

Jiwoo Shin, Geun Hee Seol, Yoo Jin Kim, Hayeong Jeon

An efficient ranking deep neural network algorithm for the prediction of Ca²⁺ binding sites of the protein

Pritee Parwekar, Samudrala Gourinath, [ ... ], Asmir Butkovic

Integrating dynamic modeling of signaling pathways with subject-specific transcriptomic data to assess breast cancer risk

Piyanut Ratphibun Yamashita, Anuwat Tangthanawatsakul, [ ... ], Teeraphan Laomettachit

Molecular regulatory mechanism of TRPV4-mediated calcium-dependent 5-HT secretion from enterochromaffin cells and its involvement in ulcerative colitis

Shuo Tong, Yujuan Wang, [ ... ], Hui Dong

Ortholog transfer stress test: Regulatory edge conservation across species, tissues, and evolutionary distance

Ihor Kendiukhov

Mechanistic insights into daidzin from Glycine max against breast cancer via network pharmacology and multi-level molecular modeling

Lan Thi Vu, Luong Trong Vu, [ ... ], Mau Hoang Chu

Exploring the Role of Nesprin1 in isoproterenol-induced heart failure: Insights into pathogenesis and therapeutic implications

Qin Qin, Cenyuan Dong, [ ... ], Lin Teng

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