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Ras signaling

Rabex-5 E3 and Rab5 GEF domains differ in their regulation of Ras, Notch, and PI3K signaling in Drosophila wing development

Theresa A. Reimels, Mia Steinberg, [ ... ], Cathie M. Pfleger

Treatment of a mutant KRAS lung cancer cell line with polyisoprenylated cysteinyl amide inhibitors activates the MAPK pathway, inhibits cell migration and induces apoptosis

Matthew D. Gregory, Kweku Ofosu-Asante, [ ... ], Nazarius S. Lamango

Autophagy-associated biomarkers ULK2, UVRAG, and miRNAs miR-21, miR-126, and miR-374: Prognostic significance in glioma patients

Wajiha Amin, Syed Ather Enam, [ ... ], Nouman Mughal

CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting

Kelly Lim, Winnie L. Kan, [ ... ], Daniel Thomas

A semantics, energy-based approach to automate biomodel composition

Niloofar Shahidi, Michael Pan, [ ... ], David P. Nickerson

Potential of phenothiazines to synergistically block calmodulin and reactivate PP2A in cancer cells

Ganesh Babu Manoharan, Sunday Okutachi, Daniel Abankwa

Pentoxifylline-induced protein expression change in RAW 264.7 cells as determined by immunoprecipitation-based high performance liquid chromatography

Mi Hyun Seo, Dae Won Kim, Yeon Sook Kim, Suk Keun Lee

Network pharmacology and molecular docking reveal the effective substances and active mechanisms of Dalbergia Odoriferain protecting against ischemic stroke

Kedi Liu, Xingru Tao, [ ... ], Miaomiao Xi

Role of Ras in regulation of intestinal epithelial cell homeostasis and crosstalk with Wnt signaling

Takenori Kotani, Noriko Ihara, [ ... ], Takashi Matozaki

Inhibition of PI3K and MAPK pathways along with KIT inhibitors as a strategy to overcome drug resistance in gastrointestinal stromal tumors

Anu Gupta, Shuang Ma, [ ... ], Brian P. Rubin

Extracellular vesicle-enriched miRNA profiles across pregnancy in the MADRES cohort

Helen Bermudez Foley, Caitlin G. Howe, [ ... ], Carrie V. Breton

4-hexylresorcinol-induced protein expression changes in human umbilical cord vein endothelial cells as determined by immunoprecipitation high-performance liquid chromatography

Yeon Sook Kim, Dae Won Kim, Seong-Gon Kim, Suk Keun Lee

Identifying the key regulators that promote cell-cycle activity in the hearts of early neonatal pigs after myocardial injury

Eric Zhang, Thanh Nguyen, [ ... ], Gregory P. Walcott

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