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Signal inhibition

Early potential safety signals for gliptins and gliflozins using real-world pharmacy data compared to spontaneous reporting

Maria-Isabel Jimenez-Serrania, Sara-Maria Martinez-Gonzalez, Javier Herradon-Muñoz, Carlos Treceño-Lobato

Omipalisib reduces hyperphosphorylated tau protein by modulating mTOR-autophagy pathway

Haeun Hwang, Namkwon Kim, [ ... ], Jong Kil Lee

Ivermectin inhibits ER, HER2, and TGF-β pathways in ER-positive and endocrine-resistant breast cancer cells

Kitiya Rujimongkon, Patthamapon Adchariyasakulchai, [ ... ], Wannarasmi Ketchart

ATG7 vs. ATG5: Distinct autophagy pathways shaping TGF-β signaling and endothelial function

Aman Singh, Bharatsinai Peddi, [ ... ], Krishna K. Singh

Gastrodin alleviates neuronal damage in epileptic cell models by targeting P2RY12 to inhibit microglial hyperactivation

Aiyuan Cai, Zilong Li, [ ... ], Haixia Wu

Wnt/β-catenin signalling modulates the timing of cell fate decision making in the early mouse embryo

Joaquin Lilao-Garzón, Elena Corujo-Simon, [ ... ], Silvia Muñoz-Descalzo

Gastrin ameliorates heart failure and suppresses myocardial remodeling via the JAK2/STAT3 and ERK1/2 pathways

Yalu Du, Ning Wang, [ ... ], Jinjing Yang

Mechanism of action of cisplatin on Na⁺/K⁺ ATPase of Caco-2 colon cells in vitro

Rida Mourad, Rawad Hodeify, Sawsan Kreydiyyeh

Strategic selection of MDM2 inhibitors enhances the efficacy of FAK inhibition in mesothelioma based on TP53 genotype

Xuerao Ning, Thảo Thi Thanh Nguyễn, [ ... ], Masatoshi Tagawa

Autapses enable temporal pattern recognition in spiking neural networks

Muhammad Yaqoob, Volker Steuber, Borys Wróbel

Inhibition of TREM1 attenuates myocardial ischemia-reperfusion injury-induced cardiomyocyte pyroptosis by suppressing the activation of the NF-κB signaling pathway

Xiaohui Xu, Liang Cai, [ ... ], Junjie Kou

Therapeutic mechanisms of genistein in ischemic stroke: A systematic review of in vivo and in vitro studies

Nurin Yasmin Mohd Khairudin, Awla Mohd Azraai, Rosfaiizah Siran, Nasibah Azme

Safety profile of TNF- alpha Inhibitors in pediatric patients: A post-marketing surveillance study based on the FAERS database

Yanmo Yang, Peng Wang, Qin-xuan Li

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