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Signaling molecules

Disruption of epidermal growth factor receptor signaling and cytoskeletal dynamics by mebendazole and gefitinib synergistically impairs paracrine cytokine signaling in non-small cell lung cancer and triple-negative breast cancer Cell lines

Mohamed El-Tanani, Shakta Mani Satyam, [ ... ], Frezah Muhana

Impact of substrate choice on human osteoclast differentiation and secretome: Implications for targeted therapeutic development

Fernanda D’Amélio, Hugo Vigerelli, [ ... ], Irina Kerkis

Mapping spatiotemporal distribution of forest carbon density in Xizang, China

Li Cheng, Zi ling Yang, [ ... ], Jiang ping Fang

3-O-acetylrubiarbonol B preferentially targets EGFR and MET over rubiarbonol B to inhibit NSCLC cell growth

A-Young Nam, Sang Hoon Joo, [ ... ], Jung-Hyun Shim

Rabex-5 E3 and Rab5 GEF domains differ in their regulation of Ras, Notch, and PI3K signaling in Drosophila wing development

Theresa A. Reimels, Mia Steinberg, [ ... ], Cathie M. Pfleger

A comparative analysis of attitudes toward genome-edited food among Japanese public and scientific community

Ryuma Shineha, Kohei F. Takeda, Yube Yamaguchi, Nozomu Koizumi

Point mutations in Arf1 reveal cooperative effects of the N-terminal extension and myristate for GTPase-activating protein catalytic activity

Eric M. Rosenberg Jr., Xiaoying Jian, [ ... ], Paul A. Randazzo

Clinical indicators combined with S100A12/TLR2 signaling molecules to establish a new scoring model for coronary artery lesions in Kawasaki disease

Yali Wu, Shasha Wang, [ ... ], Yan Ding

Regulation of the two-pore domain potassium channel, THIK-1 and THIK-2, by G protein coupled receptors

Michihiro Tateyama, Yoshihiro Kubo

Obscurin Rho GEF domains are phosphorylated by MST-family kinases but do not exhibit nucleotide exchange factor activity towards Rho GTPases in vitro

Daniel Koch, Ay Lin Kho, [ ... ], Mathias Gautel

Clinical implication and potential function of ARHGEF6 in acute myeloid leukemia: An in vitro study

Kang Li, Haiquan Wang, [ ... ], Jiankui Zhou

Computational capabilities of a multicellular reservoir computing system

Vladimir Nikolić, Moriah Echlin, Boris Aguilar, Ilya Shmulevich

Unusual enantiomeric D,L-N-acyl homoserine lactones in Pectobacterium atrosepticum and Pseudomonas aeruginosa

Umang Dhaubhadel, Abiud E. Portillo, [ ... ], Daniel W. Armstrong

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