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Oncogenic signaling

In-silico target prediction and pathway analysis of propranolol as a potential therapeutic agent for hepatocellular carcinoma

Ishaq Ahmad, Shakeel Ahmad Khan, [ ... ], Abdul Wasy Zia

Blockade of interleukin-6 (IL-6) signaling in dedifferentiated liposarcoma (DDLPS) decreases mouse double minute 2 (MDM2) oncogenicity via alternative splicing

Abeba Zewdu, Danielle Braggio, [ ... ], Raphael E. Pollock

Integrative network toxicology and molecular docking reveal 4-Nonylphenol’s multifaceted mechanisms in breast cancer pathogenesis

Congli Jia, Fu Yang

Comparative genomic landscape of lower-grade glioma and glioblastoma

Xinxin Sun, Qingbin Jia, [ ... ], Mingliang Gu

ARID1A loss is associated with increased NRF2 signaling in human head and neck squamous cell carcinomas

Vinh Nguyen, Travis P. Schrank, Michael B. Major, Bernard E. Weissman

Oncogenic mutations in IKKβ function through global changes induced by K63-linked ubiquitination and result in autocrine stimulation

April N. Meyer, Leandro H. Gallo, [ ... ], Daniel J. Donoghue

Activation of the G_i protein-RHOA axis by non-canonical Hedgehog signaling is independent of primary cilia

Lan Ho Wei, Mohammad Arastoo, [ ... ], Natalia A. Riobo-Del Galdo

¹⁸F-FDG PET intensity correlates with a hypoxic gene signature and other oncogenic abnormalities in operable non-small cell lung cancer

Brendan T. Heiden, Guoan Chen, [ ... ], Rishindra M. Reddy

Comprehensive analysis of T cell leukemia signals reveals heterogeneity in the PI3 kinase-Akt pathway and limitations of PI3 kinase inhibitors as monotherapy

Olga Ksionda, Marsilius Mues, [ ... ], Jeroen P. Roose

The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia

Sung Hee Choi, Eric Severson, [ ... ], Stephen C. Blacklow

M-COPA suppresses endolysosomal Kit-Akt oncogenic signalling through inhibiting the secretory pathway in neoplastic mast cells

Yasushi Hara, Yuuki Obata, [ ... ], Ryo Abe

Overexpression of NOTCH-regulated Ankyrin Repeat Protein is associated with papillary thyroid carcinoma progression

Mingdi Zhang, Yiyu Qin, [ ... ], Bingfeng Chu

Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway

Hsien-Chuen Soo, Felicia Fei-Lei Chung, [ ... ], Chun-Wai Mai

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