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Cell signaling

Assessing the real-world safety of vutrisiran for transthyretin-mediated amyloidosis with polyneuropathy: Based on WHO-VigiAccess and FAERS databases

Weiwei Tong, Yaxing Li, Xingli Xu, Yang Mao, Ruonan Zhang, Chuanliang Zhao, Jidang Zhang, Chigang Du, Jiayue Feng

published 15 Apr 2026

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NSUN4-mediated m5C RNA methylation protects retinal cells against excitotoxic injury via the SHH signaling pathway

Yahong Li, Dian Li, Chao Geng, Ruihua Wei, Yajian Duan

published 15 Apr 2026

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Network pharmacological insight into traditional bone healing practices of Sikkim, India

Mukunda Anuj Sharma, Bharat Gopalrao Somkuwar, Parvin A. Barbhuiya, Bhumika Gurung, Madhusmita Mahapatra, Firdous Fatima, Teresa Ningthoujam, Ashika Bhattarai, Bikash Rai, Pravin Kumar, Bishal Tiwari, Sancha Kumar Subba, Zyankit Lepcha, Purna Maya Gurung, Nandalal Khadka, Ratan Bahadur Tamang, Balbir Khati, Shribhakta Chettri, Ran Bahadur Rai, Hem Lall Sharma, Yam Bahadur Rai, Norzang Lepcha, Theptuk Lepcha, Pritiman Singh Chettri, Monraj Limboo, Theweng Gyenthen, Tulshi Pradhan, Prem Gurung, Prem Prashad Dhakal, Nanaocha Sharma, Lokesh Deb

published 15 Apr 2026

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Role of AtCPK5 and AtCPK6 in the regulation of the plant immune response triggered by rhamnolipids in Arabidopsis

Juliette Stanek, Olivier Fernandez, Marie Boudsocq, Dina Aggad, Sandra Villaume, Laetitia Parent, Sandrine Dhondt-Cordelier, Jérôme Crouzet, Stéphan Dorey, Sylvain Cordelier

published 13 Apr 2026

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IGF1/IGF-1R promotes hepatocellular carcinoma progression by activating the Akt/GSK-3β pathway

Jiaojiao Liang, Xueyi Song, Yang Liu, Guoyu Yang, Bairu Zhu, Xiaolong Tang

published 09 Apr 2026

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Peripheral modulation of Pumilio in intestinal stem cells and the corpus allatum affects sleep latency in Drosophila

Josué A. Rodríguez-Cordero, Marialena Dorta Avilés, Imilce A. Rodriguez-Fernandez, Alfredo Ghezzi, José E. Lizardi-Ortiz, José L. Agosto-Rivera

published 08 Apr 2026

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Metformin attenuates TBHP-induced oxidative injury in human lens epithelial cells and is associated with SIRT1/FOXO1-related autophagy

Zhuxuan Yan, Wei Chi, Zhenguo Yan, Hanrui Wang

published 07 Apr 2026

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Mapping the role of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its receptors in chronic kidney disease: A scoping review protocol

Hansani Niroshika, Harshi Weerakoon, Nalaka Herath, Kosala Weerakoon, Prasad Jayasooriya

published 07 Apr 2026

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Association between chronic stress and the epigenome: Exploration of psychological and biological stress

Melissa Miller, Robin D. Brown, Cole Krautkramer, Rhea Gogia, Hagen Fritz, Dennis Wylie, Kerry Kinney, Frances A. Champagne

published 06 Apr 2026

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Hepatic transcriptomic responses in gravid and non-gravid rats exposed to HFPO-DA: Analyses to inform the role of maternal effects in neonatal toxicity

Melissa M. Heintz, Chad M. Thompson, Jeffrey C. Wolf, John M. Rogers, Laurie C. Haws

published 01 Apr 2026

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Deciphering the synergistic mechanism of a novel flavonoid-antioxidant combination for asthma by combining systems pharmacology and experimental validation

Ziyi Chen, Xinling Ren, Xiaoyu Liu, Lifeng Tian, Yun Huang, Aiping Lyu, Wei Zhou

published 30 Mar 2026

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Composite selection signal analysis: Uncovering candidate genes and quantitative trait loci in Indian sheep breeds

Sapna Nath, Satish Kumar Illa, Destaw Worku, Sabyasachi Mukherjee, Anupama Mukherjee, Vinod Kumar Yata

published 25 Mar 2026

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Non-invasive host transcriptome and HPV oncogene expression map the molecular landscape of HPV-driven cervical lesions

Mohamad Ammar Ayass, Naila Zaman, Natalya Griko, Victor Pashkov, Kevin Zhu, Ghulam Abbas, Melesse Ghelan, Ramya Ramankutty Nair, Tutku Okyay, Jin Zhang, Lina Abi-Mosleh

published 19 Mar 2026

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