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Cell signaling

Mechanistic insights into daidzin from Glycine max against breast cancer via network pharmacology and multi-level molecular modeling

Lan Thi Vu, Luong Trong Vu, [ ... ], Mau Hoang Chu

Exploring the Role of Nesprin1 in isoproterenol-induced heart failure: Insights into pathogenesis and therapeutic implications

Qin Qin, Cenyuan Dong, [ ... ], Lin Teng

Reproductive-state dependent changes in inner ear gene expression in female plainfin midshipman fish

Coty Jasper, Sumaya Hassan, [ ... ], Allison B. Coffin

Functional CCR7A-mediated cellular responses are negatively modulated by the splice variant CCR7B

Minyeong Cho, Hee-Kyung Park, [ ... ], Jong-Ik Hwang

FAERS-based pharmacovigilance and network toxicology analysis of esomeprazole-associated osteoporosis

Yan Wang, Xiaolong Xu, [ ... ], Jue Lin

Integrative network pharmacology, transcriptomics, and molecular docking identify candidate Centella asiatica constituents and targets in neurodegenerative diseases

Yuxi Xie, Chong-Teik Lim, [ ... ], Tan Huang

Concordant RNA-protein evidence and human tissue metabolomics prioritize UPP1-associated nucleotide remodeling in prostate cancer

Xuancai Chen, Wei Su, [ ... ], Hao Fu

Mechanistic evaluation of NSC 57774 as a SHP2 inhibitor in gastric cancer: Multi-pathway signaling modulation in vitro

Ghalia Khoder, Rose Ghemrawi, [ ... ], Mostafa Khair

Overexpression of CD97 in intestinal epithelial cells attenuates LPS-induced pro-inflammatory cytokine induction via stabilization of β-catenin early in life

Niklas Dressler, Steffi Mayer, [ ... ], Jan Riedel

Bisphenol A exposure in myasthenia gravis: Potential targets and mechanisms revealed by network toxicology and molecular dynamics

Shupeng Wu, Yaoqi Wu, Li Zhang, Jun Zhu

Helminth-derived stefin-1 selectively reduces leukemic cell viability and promotes apoptosis in U937 cells

Phornthip Ploensil, Yaneenart Suwanwong, [ ... ], Pathanin Chantree

G-protein coupled receptor, signal and signal-transduction related transcript mapping in nigral volume and pigmented neurons reveals a potential deficit of nigral feedback signals associated with Parkinson’s disease

John M. Haynes

Signal mining and analysis of adverse events associated with Isotretinoin: A 20-Year real-world pharmacovigilance study based on FAERS and EudraVigilance databases

Qian Chen, JinYue Li, [ ... ], HongLi Luo

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