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Membrane receptor signaling

Safety profile of entrectinib in NSCLC: Multi-source pharmacovigilance analysis using FAERS and JADER

JiaLe Yang, JiaWen Liu, [ ... ], Ge Sun

Nasal exposure to PM2.5 induces testicular injury and activation of pyroptosis-related signaling in rats: Inhibitor intervention and public transcriptomic analysis

Yi Luo, Cao Wang, [ ... ], Ma Hong

A multimodal analysis suggests partial IRF8/TLR7-associated myeloid transcriptional convergence between diabetic kidney disease and Parkinson’s disease

Xue Hu, Yingzhuo Li, [ ... ], Jiaping Wang

Molecular regulatory mechanism of TRPV4-mediated calcium-dependent 5-HT secretion from enterochromaffin cells and its involvement in ulcerative colitis

Shuo Tong, Yujuan Wang, [ ... ], Hui Dong

Functional CCR7A-mediated cellular responses are negatively modulated by the splice variant CCR7B

Minyeong Cho, Hee-Kyung Park, [ ... ], Jong-Ik Hwang

FAERS-based pharmacovigilance and network toxicology analysis of esomeprazole-associated osteoporosis

Yan Wang, Xiaolong Xu, [ ... ], Jue Lin

Concordant RNA-protein evidence and human tissue metabolomics prioritize UPP1-associated nucleotide remodeling in prostate cancer

Xuancai Chen, Wei Su, [ ... ], Hao Fu

Overexpression of CD97 in intestinal epithelial cells attenuates LPS-induced pro-inflammatory cytokine induction via stabilization of β-catenin early in life

Niklas Dressler, Steffi Mayer, [ ... ], Jan Riedel

Bisphenol A exposure in myasthenia gravis: Potential targets and mechanisms revealed by network toxicology and molecular dynamics

Shupeng Wu, Yaoqi Wu, Li Zhang, Jun Zhu

Signal mining and analysis of adverse events associated with Isotretinoin: A 20-Year real-world pharmacovigilance study based on FAERS and EudraVigilance databases

Qian Chen, JinYue Li, [ ... ], HongLi Luo

Mycobacterial lipoarabinomannan negatively interferes with macrophage responses to Aspergillus fumigatus in-vitro

Luis E. Gonzales-Huerta, Thomas J. Williams, [ ... ], Darius P. H. Armstrong-James

AI-driven molecular diversification and ligand-based optimization of macitentan derivatives targeting VEGFR1 and endothelin signaling pathways

Sümeyra Koç Sahin, Nouman Ali

Drug-induced gastric motility disorders: A disproportionality analysis from the FAERS and CVARD databases

Zhiheng Qian, Ni Jiang

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