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Membrane receptor signaling

Functional CCR7A-mediated cellular responses are negatively modulated by the splice variant CCR7B

Minyeong Cho, Hee-Kyung Park, [ ... ], Jong-Ik Hwang

FAERS-based pharmacovigilance and network toxicology analysis of esomeprazole-associated osteoporosis

Yan Wang, Xiaolong Xu, [ ... ], Jue Lin

Concordant RNA-protein evidence and human tissue metabolomics prioritize UPP1-associated nucleotide remodeling in prostate cancer

Xuancai Chen, Wei Su, [ ... ], Hao Fu

Overexpression of CD97 in intestinal epithelial cells attenuates LPS-induced pro-inflammatory cytokine induction via stabilization of β-catenin early in life

Niklas Dressler, Steffi Mayer, [ ... ], Jan Riedel

Bisphenol A exposure in myasthenia gravis: Potential targets and mechanisms revealed by network toxicology and molecular dynamics

Shupeng Wu, Yaoqi Wu, Li Zhang, Jun Zhu

Signal mining and analysis of adverse events associated with Isotretinoin: A 20-Year real-world pharmacovigilance study based on FAERS and EudraVigilance databases

Qian Chen, JinYue Li, [ ... ], HongLi Luo

Mycobacterial lipoarabinomannan negatively interferes with macrophage responses to Aspergillus fumigatus in-vitro

Luis E. Gonzales-Huerta, Thomas J. Williams, [ ... ], Darius P. H. Armstrong-James

AI-driven molecular diversification and ligand-based optimization of macitentan derivatives targeting VEGFR1 and endothelin signaling pathways

Sümeyra Koç Sahin, Nouman Ali

Drug-induced gastric motility disorders: A disproportionality analysis from the FAERS and CVARD databases

Zhiheng Qian, Ni Jiang

Transcriptomic profile of the hippocampus of rat strains with contrasting nervous system excitability

Marina Pavlova, Irina Shalaginova, Natalia Dyuzhikova

Identification of drug-related cardiovascular risks: A comprehensive analysis using the FAERS database (2004–2024)

Naishen Qin, Yumei Gan, [ ... ], Jiangnan Huang

Viral dsRNA triggers human fetal membrane miR-146a-3p to be packaged into small extracellular vesicles which in turn drives inflammation through activation of Toll-like Receptor 7 and 8

Hanah M. Georges, Abigail C. Fischer, Paloma Casanova, Vikki M. Abrahams

Effects of bulevirtide on atherosclerosis in an ApoE-deficient mouse model

Jonas Rusnak, Victoria Delcheva, [ ... ], Michael R. Preusch

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