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Genome analysis

Single-cell transcriptomics and machine learning characterize LTA4H-linked lipid metabolism and inflammatory signatures in the knee osteoarthritis IPFP/synovium compartment

Xin Chen, Shudong Li, [ ... ], Jifeng Zhao

Omicron SARS-CoV-2 shows NRP1-linked susceptibility in adipose-derived MSCs and alters primitive cord blood CD34⁺ HSPCs

Kanit Bhukhai, Nopmullee Tanhuad, [ ... ], Arunee Thitithanyanont

Integrated bioinformatics analysis identifies an immune-related gene signature associated with non-obstructive azoospermia

Yucheng Zhong, Songqing Ye, [ ... ], Xiaofu Qiu

Benchmarking ensemble and deep learning models for drought-responsive gene prioritisation in rice using multi-omics data

Kumanan N. Govaichelvan, Dharini Pathmanathan, Rabiatul Adawiah Zainal-Abidin, Arpah Abu

Intercellular GAS6-AXL signaling triggers podocyte cuproptosis in acute kidney injury upstream regulated by CEBPD

Jingmei Liang, Yuyun Hu, Bing Liao

Transcriptomic analysis of zebrafish (Danio rerio) liver exposed to sediments from the Loa River

Nataly Lobos-Parra, Natalia V. Leiva, [ ... ], Rodrigo Orrego

Identification of shared diagnostic biomarkers and immune-related mechanisms between sepsis and thoracic aortic aneurysm based on integrated bioinformatics and machine learning approaches

Chengqun She, Hao Deng, [ ... ], Juan Wu

Genomic inbreeding and selection signatures analyses in the Doberman Pinscher breed

Henrique Mulim-McCarthy, Breno Fragomeni, Sophie Liu, Hinayah Rojas de Oliveira

Genomic diversity, host associations, and tissue tropism of Hydrangea ringspot virus: A global and regional perspective

Juliana Osorio-Marulanda, Juliana Lopez-Jimenez, Juan F. Alzate

Integrative transcriptomics identifies an 18-gene candidate blood-accessible biomarker panel for longitudinal monitoring of spaceflight-induced muscle atrophy

Jae Ho Shim, Ji Yeon Lee, Jihye Han, Hyeon Soo Kim

Shenling Qige Granules inhibit esophageal squamous cell carcinoma progression in TE-1 xenograft and cell-based models by modulating the DCN–TGF-β/Smad signaling axis

Zihui Liu, Yiting Gu, [ ... ], Zhihua Du

Integrated multi-omic analysis characterizes an IFNγ-responsive-to-myeloid-suppressive immune continuum in immune-active hepatocellular carcinoma

Luping Lin, Ningna Weng, [ ... ], Xiao Chen

GP-DHT: A dual-head transformer with supervised contrastive learning for shared-gene pretraining and single-cell GRN prediction

Shuai Yan, Qingzhi Yu, Wenfeng Dai, Xiang Cheng

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